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Hetlioz LQ

Hetlioz LQ (tasimelteon) is a melatonin receptor agonist used primarily for the treatment of non-24-hour sleep-wake disorder in blind individuals who have an absence of light perception. It helps regulate the sleep-wake cycle by acting on melatonin receptors in the brain, promoting sleep and improving overall sleep quality.



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Frequently Asked Questions

How quickly does Hetlioz LQ work?
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Patients may begin to notice improvements in their sleep patterns within a few days of starting the medication, but it may take longer for some individuals.

How quickly does Hetlioz LQ work?
Open FAQClose FAQ

Patients may begin to notice improvements in their sleep patterns within a few days of starting the medication, but it may take longer for some individuals.

Can I take Hetlioz LQ if I am pregnant?
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Consult your healthcare provider for guidance, as the use during pregnancy should be evaluated based on risks and benefits.

What should I do if I miss a dose?
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If you miss a dose, take it as soon as you remember on the same night. If it's close to your next scheduled dose, skip the missed dose and continue with your regular schedule.

What should I do if I miss a dose?
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If you miss a dose, take it as soon as you remember on the same night. If it's close to your next scheduled dose, skip the missed dose and continue with your regular schedule.

Are there any specific storage instructions for Hetlioz LQ?
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Store at room temperature, away from moisture and direct sunlight. Keep out of reach of children.

Is Hetlioz LQ safe for long-term use?
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Long-term use should be monitored by a healthcare provider to assess efficacy and minimize the risk of side effects.

Comprehensive Drug Guide

How Does Hetlioz LQ Work?

Hetlioz LQ works by selectively binding to and activating melatonin receptors (MT1 and MT2) in the suprachiasmatic nucleus of the brain. This action mimics the effects of natural melatonin, helping to regulate circadian rhythms and facilitate sleep onset.

Common Dosages

  • Oral liquid solution: Common dosage is 20 mg/mL.

Typical Dosing

The typical dosing for Hetlioz LQ is:

  • For Non-24-Hour Sleep-Wake Disorder: The recommended dose is 20 mg taken orally once daily at bedtime.


Typical Dosing

FDA Approved Indications

  • Treatment of non-24-hour sleep-wake disorder in blind individuals.


Who Shouldn't Take Hetlioz LQ?

  • Hypersensitivity: Known hypersensitivity to tasimelteon or any components of the formulation.
  • Severe Liver Impairment: Should be used with caution in patients with liver impairment.


Advice From The Pharmacist

  • How to Use: Take Hetlioz LQ approximately 30 minutes before bedtime. Shake the bottle well before each use to ensure proper dosing.
  • Monitor for Side Effects: Patients should be monitored for signs of excessive drowsiness or other side effects.
  • Avoid Alcohol: Alcohol can interfere with sleep patterns and should be avoided while taking this medication.


Side Effects of Hetlioz LQ

Common Side Effects

  • Drowsiness
  • Headache
  • Fatigue
  • Nausea


Uncommon/Severe Side Effects

  • Severe allergic reactions: Such as rash, itching, or difficulty breathing.
  • Abnormal dreams or sleep disturbances.


Risks and Warnings of Hetlioz LQ

  • Caution with Activities: Patients should be cautious when driving or operating machinery until they know how Hetlioz LQ affects them.
  • Drug Interactions: Use with caution in patients taking other medications that affect the central nervous system.


Interactions with Hetlioz LQ

Common Drug Interactions

  • Drug Interactions: Hetlioz LQ may interact with other medications that induce or inhibit liver enzymes, such as certain antifungals or antibiotics. Always inform your healthcare provider about all medications you are taking.


Alternatives to Hetlioz LQ

  • Other Sleep Aids: Such as zolpidem or eszopiclone.
  • Melatonin Supplements: Over-the-counter melatonin products for sleep regulation.