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Glycate
Glycate is an oral medicine designed to aid in the management of blood sugar levels in individuals with type 2 diabetes, working by slowing down the breaking down and absorption of carbohydrates from your meals. Common side effects may include gas, diarrhea, or abdominal discomfort, but these are usually temporary and subside as the body adjusts to the drug.
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Frequently Asked Questions
Can Glycate be used during pregnancy?
The full effects of Glycate on an unborn child are unknown. Therefore, it should be used in pregnancy only if needed.
Can I take Glycate even if I'm not diabetic?
Glycate is recommended only to individuals diagnosed with Type 2 or sometimes Type 1 diabetes. It should not be used by individuals without these conditions.
I forgot to take my dose of Glycate, what should I do?
If you missed a dose, it is advisable to take it as soon as possible with a meal. However, if it's almost time for the next dose, skip the missed dose and go back to your regular schedule.
Comprehensive Drug Guide
How Does Glycate Work?
Glycate is an oral antihyperglycemic agent that interrupts the digestion of complex carbohydrates and disaccharides by inhibiting the alphaglucosidase enzyme, thus attenuating the postprandial rise in blood glucose.
What is Glycate Used For?
FDA indications: Glycate is used together with diet and exercise to improve blood glucose control in adults with type 2 diabetes mellitus.
Offlabel uses: Whilst Glycate is predominantly used for type 2 diabetes, it may be recommended as adjunctive therapy in type 1 diabetes for some patients.
Common Dosages
Tablets: 25mg, 50mg, 100mg
Typical Dosing
FDA Approved Indications
- Type 2 diabetes: The recommended starting dose is 25 mg orally 3 times a day with meals; this might be increased to 100mg 3 times a day.
Off-Label Uses
- For hepatic encephalopathy: 30 to 45 mL three times a day.
Who Shouldn't Take Glycate?
- Have Diabetic Ketoacidosis.
- Have inflammatory bowel disease, colonic ulceration, or partial intestinal obstruction.
- Have chronic intestinal diseases associated with marked disorders of digestion or absorption.
- Have conditions that may deteriorate as a result of increased gas formation in the intestine.
- Are Pregnant or planning to become pregnant. The full risks to the unborn child from Glycate are not currently known and therefore, it should be used in pregnancy only if needed.
Advice From The Pharmacist
- Take Glycate with the first bite of each main meal.
- Stomach upset, diarrhea, and gas may occur during the first few weeks of treatment but usually improve with time.
- Taking Glycate in smaller doses, and increasing the dose gradually may help prevent side effects.
- If you're a beer or wine sipper, be cautious. Alcohol can worsen the side effects of Glycate.
- If you skip a meal or your meal contains no carbs, don't take Glycate.
Side Effects of Glycate
Common Side Effects
- Gas.
- Diarrhea.
- Abdominal discomfort.
Uncommon/Severe Side Effects
- Uncommon side effects:
- Skin rash.
- Reducing the dose or taking Glycate with meals can help manage its side effects.
Risks and Warnings of Glycate
- Glycate usage is not advised during surgery or any condition that might alter digestion and absorption.
- Hypoglycemia may occur when Glycate is used together with certain other antidiabetic medications. Dosage adjustments might be necessary in these instances.
- Careful monitoring of liver functions is advised for users of Glycate, especially those with preexisting liver conditions.
Interactions with Glycate
Common Drug Interactions
- Drugs delaying absorption such as Acarbose
- Digoxin
- Warfarin
- Ranitidine
Alternatives to Glycate
- Acarbose
- Precose
