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glipiZIDE XL
Glipizide is an oral medication used to control blood sugar levels in people with type 2 diabetes, it falls under the category of drugs known as sulfonylureas which stimulate the pancreas to release more insulin. Common side effects include dizziness, diarrhea, and headache, but your healthcare provider will ensure that the benefits of the drug outweigh these minor issues.
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Frequently Asked Questions
Can Glipizide be taken with insulin?
Yes, Glipizide can be used in combination with insulin in patients who are not achieving adequate blood sugar control on insulin alone.
Can Glipizide cause hypoglycemia?
Yes, one of the side effects of Glipizide is hypoglycemia or low blood sugar. It's important to recognize the symptoms of hypoglycemialike sweating, trembling, hunger, and confusionand take corrective measures promptly.?
Can Glipizide cause weight gain?
Yes, weight gain is a common side effect of Glipizide and other sulfonylureas.?
Can I stop taking Glipizide abruptly?
No, you should not stop taking Glipizide abruptly as this could cause your blood sugar to spike. Consult your healthcare provider for advice on discontinuing or reducing the dose safely.?
Does Glipizide need to be taken with food?
Yes, Glipizide should be taken about 30 minutes before a meal.
Is Glipizide safe during pregnancy?
Glipizide falls under the FDA's Category C for pregnancy. This means potential benefits may warrant the use of the drug in pregnant women despite potential risks. It's advisable to consult with your healthcare provider for the best course of action.
Comprehensive Drug Guide
How Does glipiZIDE XL Work?
Glipizide is an oral antidiabetic medication that stimulates the release of insulin from the beta cells of the pancreas. It works by increasing the sensitivity of insulin receptors thereby ensuring more effective utilization of circulating insulin.
What is glipiZIDE XL Used For?
FDA indications: Glipizide is used to control high blood sugar in people with type 2 diabetes. It's often used alongside a proper diet and exercise to control diabetes effectively.
Offlabel uses: It's not commonly used offlabel. But as a sulfonylurea, it's primarily used to control high blood sugar levels in type 2 diabetes patients.
Common Dosages
Tablets: 5mg, 10mg
Extended Release Tablets: 2.5mg, 5mg, 10mg
Typical Dosing
FDA Approved Indications
- FDAapproved indications:
- Diabetes management: Start with 5mg per day, which can be increased every few days but not more than 40mg per day.
Off-Label Uses
- Offlabel uses: It's not commonly used offlabel. But as a sulfonylurea, it's primarily used to control high blood sugar levels in type 2 diabetes patients.
Who Shouldn't Take glipiZIDE XL?
- Persons allergic to sulfonylureas.
- Those with diabetic ketoacidosis.
- Anyone with type 1 diabetes.
- Pregnant women, unless necessary.
- Those with severe kidney or liver disease.
- Persons with G6PD deficiency.
Advice From The Pharmacist
- Maintain a regular exercise routine and diet to ensure wellmanaged blood sugar levels.
- Take Glipizide about 30 minutes before a meal.
- Regular blood sugar testing is advised to adjust your dosage according to your needs.
- Don't suddenly stop taking the drug as it can lead to high blood sugar levels.
- Report any symptoms of hypoglycemia like shaking, excessive sweating, or rapid heartbeat.
- It is important to maintain regular doctor appointments for checkups and blood tests.
Side Effects of glipiZIDE XL
Common Side Effects
- Common side effects: Dizziness, diarrhea, and tremors.
Uncommon/Severe Side Effects
- Rare side effects: Yellowing of the skin or eyes (jaundice).
- Severe side effects: Unusual tiredness, dark urine, and allergic reaction signs like swelling face/lips, dizziness, and difficulty in breathing.
Risks and Warnings of glipiZIDE XL
- Extra caution is advised when using glipizide if you have a history of liver or kidney disease, heart disease, G6PD deficiency, or hormonal disorders.
- Elderly patients are more likely to have reduced kidney function and require dosage adjustment.
- Hypoglycemia, or low blood sugar, is a major concern and constant sugar monitoring is necessary.
Interactions with glipiZIDE XL
Common Drug Interactions
- BetaBlockers
- AntiFungal Medications
- Common Food Interactions
- Avoid consumption of alcohol as it can lower your blood sugar excessively.
Alternatives to glipiZIDE XL
- Metformin
- Insulin
- DPP4 Inhibitors
