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Fycompa
Fycompa (generic name: perampanel) is an antiepileptic drug (AED) used to treat partial-onset seizures and primary generalized tonic-clonic seizures in patients with epilepsy aged 12 years and older. It works by targeting AMPA receptors in the brain, reducing excessive neuronal activity associated with seizures.
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Frequently Asked Questions
How long does it take for Fycompa to work?
It may take several days to weeks for Fycompa to start reducing seizure frequency. Your healthcare provider will monitor your response to the medication.
Can Fycompa cause weight gain?
Yes, weight gain is a common side effect of Fycompa.
Can I drink alcohol while taking Fycompa?
It is not recommended to drink alcohol while taking Fycompa, as it can increase side effects like drowsiness and impaired coordination.
What should I do if I miss a dose of Fycompa?
If you miss a dose, take it as soon as you remember. If it’s almost time for the next dose, skip the missed dose and resume your normal schedule. Do not double up on doses.
Is Fycompa safe for long-term use?
Fycompa is generally considered safe for long-term use, but regular monitoring by your healthcare provider is important to assess its effectiveness and safety.
Comprehensive Drug Guide
How Does Fycompa Work?
Fycompa is a selective non-competitive AMPA receptor antagonist. It inhibits the activity of AMPA receptors, which play a key role in the transmission of excitatory signals in the brain. This reduces the likelihood of seizures in patients with epilepsy.
Common Dosages
- 2 mg, 4 mg, 6 mg, 8 mg, 10 mg, and 12 mg oral tablets
- 0.5 mg/mL oral suspension
Typical Dosing
- The typical starting dose is 2 mg once daily, which can be increased gradually based on response and tolerance.
Typical Dosing
FDA Approved Indications
- Partial-onset seizures with or without secondary generalized seizures
- Primary generalized tonic-clonic seizures in patients with epilepsy aged 12 years and older
Who Shouldn't Take Fycompa?
- Severe liver disease
- Known hypersensitivity to perampanel
Advice From The Pharmacist
- Take Fycompa at bedtime to reduce the risk of drowsiness and dizziness during the day.
- Do not stop taking Fycompa suddenly, as this may lead to increased seizures. Consult your healthcare provider if you need to discontinue use.
- Store the oral suspension at room temperature and shake the bottle well before use.
Side Effects of Fycompa
Common Side Effects
- Dizziness
- Fatigue
- Irritability
- Weight gain
Uncommon/Severe Side Effects
- Aggressive behavior
- Suicidal thoughts
- Severe allergic reactions
Risks and Warnings of Fycompa
- Behavioral Changes: Fycompa may cause aggression, anger, and suicidal thoughts in some patients. Report any mood or behavioral changes to your healthcare provider immediately.
- Drowsiness and Dizziness: Fycompa can cause drowsiness and dizziness. Avoid driving or operating heavy machinery until you know how it affects you.
Interactions with Fycompa
Common Drug Interactions
- Alcohol: Drinking alcohol while taking Fycompa can increase the risk of drowsiness, dizziness, and impaired coordination.
- Other antiepileptic drugs (AEDs): Combining Fycompa with other AEDs can alter its effectiveness and increase side effects.
Alternatives to Fycompa
- Keppra (levetiracetam): A broad-spectrum AED used for the treatment of seizures.
- Lamictal (lamotrigine): An AED used to treat various types of seizures, including partial-onset seizures.
- Topamax (topiramate): An AED used to treat epilepsy and prevent migraines.
