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Fluzone Quadrivalent
Fluzone Quadrivalent is an influenza vaccine designed to protect against four different flu virus strains: two influenza A strains and two influenza B strains. It is intended for seasonal flu prevention in individuals aged 6 months and older. The vaccine is typically updated annually to match the flu strains expected to be most prevalent during the upcoming flu season. Fluzone Quadrivalent helps the immune system develop antibodies that fight off the flu, reducing the risk of illness and its complications.
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Frequently Asked Questions
How soon after receiving Fluzone Quadrivalent will I be protected from the flu?
It takes about 2 weeks for your body to develop antibodies and full protection after getting the vaccine.
Can I get the flu from the Fluzone Quadrivalent vaccine?
No, the virus in Fluzone Quadrivalent is inactivated (killed) and cannot cause the flu. Some mild side effects, like soreness and fever, may occur but are not the flu.
Should I get Fluzone Quadrivalent every year?
Yes, annual vaccination is recommended as the flu strains included in the vaccine are updated each year to match the strains most likely to circulate during the flu season.
Is Fluzone Quadrivalent safe for children?
Yes, Fluzone Quadrivalent is approved for use in children 6 months and older. For children receiving their first flu vaccine, a second dose may be required.
What should I do if I experience side effects from the vaccine?
Mild side effects such as soreness, fatigue, or a low-grade fever are common and should subside within a few days. If you experience more severe side effects, such as difficulty breathing or swelling, seek medical attention immediately.
Can I get the flu vaccine if I’m allergic to eggs?
Individuals with a severe egg allergy should consult their healthcare provider before getting the flu vaccine. Flublok Quadrivalent is an egg-free alternative available for such cases.
Comprehensive Drug Guide
How Does Fluzone Quadrivalent Work?
Fluzone Quadrivalent works by exposing the immune system to inactivated (killed) strains of the flu virus. This stimulates the body to produce antibodies that recognize and fight off the specific flu strains included in the vaccine. If exposed to the live virus later in the season, the immune system is prepared to attack the virus, significantly reducing the risk of developing the flu or experiencing severe symptoms.
Common Dosages
- For children aged 6 months to 8 years receiving the flu vaccine for the first time, two doses may be recommended.
- For everyone else: A single 0.5 mL dose is administered annually.
Typical Dosing
FDA Approved Indications
- Prevention of influenza (flu) in individuals aged 6 months and older.
- It is recommended for annual vaccination to protect against the flu strains expected to circulate in a given flu season.
Who Shouldn't Take Fluzone Quadrivalent?
- Severe allergic reactions (e.g., anaphylaxis) to any component of the vaccine, including eggs or egg products, or after a previous dose of any influenza vaccine.
- Guillain-Barré syndrome (GBS) within 6 weeks of receiving a previous flu vaccine (consult with a healthcare provider).
Advice From The Pharmacist
- Get vaccinated annually: Flu viruses change from year to year, so it’s important to get the vaccine before the flu season starts.
- Common side effects include mild soreness or redness at the injection site, fever, and fatigue. These symptoms usually resolve within a few days.
- You cannot get the flu from the vaccine, as the virus is inactivated (killed) in this form of the vaccine.
- Children under 9 years old receiving their first flu vaccine may need a second dose 4 weeks after the first to ensure full immunity.
Side Effects of Fluzone Quadrivalent
Common Side Effects
- Soreness, redness, or swelling at the injection site
- Mild fever
- Fatigue
- Headache
- Muscle aches
Uncommon/Severe Side Effects
- Severe allergic reactions (anaphylaxis), characterized by rash, difficulty breathing, or swelling of the face and throat.
- Guillain-Barré syndrome (GBS), a rare neurological disorder.
Risks and Warnings of Fluzone Quadrivalent
- Allergic Reactions: Individuals with a history of severe allergic reactions to flu vaccines or egg proteins should consult their healthcare provider before receiving Fluzone.
- Guillain-Barré Syndrome (GBS): In rare cases, influenza vaccines have been associated with GBS, a condition that causes muscle weakness and paralysis. If you have a history of GBS, discuss the risks with your healthcare provider.
- Flu-like Symptoms: After receiving the vaccine, you may experience mild flu-like symptoms, such as fever and body aches. These side effects are usually mild and temporary.
Interactions with Fluzone Quadrivalent
Common Drug Interactions
- Other vaccines: Fluzone Quadrivalent can be given at the same time as other vaccines, but in different injection sites.
- Immunosuppressive medications: Drugs that suppress the immune system (e.g., corticosteroids, chemotherapy) may reduce the effectiveness of the flu vaccine. Your doctor may recommend a different vaccine strategy based on your condition.
Alternatives to Fluzone Quadrivalent
- FluMist Quadrivalent: A nasal spray flu vaccine, typically used in healthy individuals aged 2 to 49, which contains live but weakened flu viruses.
- Flublok Quadrivalent: An egg-free flu vaccine option for individuals with severe egg allergies.
- Fluad Quadrivalent: A flu vaccine for adults aged 65 and older, containing an adjuvant to help improve the immune response.
