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Fluticasone Furoate-Vilanterol
Fluticasone Furoate-Vilanterol is a combination inhalation medication used for the treatment of chronic obstructive pulmonary disease (COPD) and asthma. It combines fluticasone furoate, an inhaled corticosteroid, which helps reduce inflammation, and vilanterol, a long-acting beta-agonist (LABA), which helps to relax the muscles of the airways and improve airflow. This combination is effective in managing respiratory symptoms and improving lung function.
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Frequently Asked Questions
How long does it take for Fluticasone Furoate-Vilanterol to start working?
Patients may start to notice improvement in symptoms within a few hours, but it may take several days to achieve maximum benefits.
Can I use Fluticasone Furoate-Vilanterol for an asthma attack?
No, this medication is not intended for the treatment of acute asthma attacks. Always have a rescue inhaler available for immediate relief.
What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember. If it's close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up.
Can I take Fluticasone Furoate-Vilanterol if I am pregnant?
Consult your healthcare provider for guidance if you are pregnant or planning to become pregnant, as the benefits must be weighed against potential risks.
Are there any specific storage instructions for Fluticasone Furoate-Vilanterol?
Store at room temperature, away from direct sunlight and moisture. Do not freeze.
Comprehensive Drug Guide
How Does Fluticasone Furoate-Vilanterol Work?
Fluticasone Furoate works by reducing inflammation in the airways, thereby decreasing swelling and mucus production. Vilanterol acts by stimulating beta-2 adrenergic receptors, leading to bronchodilation, or the widening of the air passages in the lungs. Together, these actions help alleviate symptoms such as wheezing, shortness of breath, and coughing.
Common Dosages
Fluticasone Furoate-Vilanterol is available in the following forms:
- Dry powder inhaler (DPI): Typically available as 100/25 mcg or 200/25 mcg (fluticasone furoate/vilanterol per inhalation).
Typical Dosing
The typical dosing for Fluticasone Furoate-Vilanterol is:
- For Asthma: Inhale one puff of the 100/25 mcg or 200/25 mcg formulation once daily.
- For COPD: Inhale one puff of the 100/25 mcg or 200/25 mcg formulation once daily.
Typical Dosing
FDA Approved Indications
- Management of asthma in patients aged 6 years and older.
- Treatment of COPD in adults.
Who Shouldn't Take Fluticasone Furoate-Vilanterol?
- Hypersensitivity: Known hypersensitivity to fluticasone, vilanterol, or any of the components of the formulation.
- Acute Asthma Exacerbations: It is not intended for the immediate relief of acute symptoms or exacerbations.
Advice From The Pharmacist
- How to Use: Use the inhaler as directed, ensuring proper technique to maximize drug delivery. Rinse your mouth after use to minimize the risk of oral thrush.
- Monitoring: Regularly monitor respiratory symptoms and lung function. Inform your healthcare provider if symptoms worsen.
- Do Not Use More Frequently: Do not exceed the prescribed dosage, as this may increase the risk of side effects.
Side Effects of Fluticasone Furoate-Vilanterol
Common Side Effects
- Throat irritation
- Cough
- Headache
- Nausea
Uncommon/Severe Side Effects
- Pneumonia: Increased risk in COPD patients.
- Adrenal insufficiency: Symptoms may include fatigue, weakness, and low blood pressure.
- Cardiovascular effects: Increased heart rate or blood pressure.
Risks and Warnings of Fluticasone Furoate-Vilanterol
- Infections: Patients should be monitored for signs of respiratory infections, including pneumonia.
- HPA Axis Suppression: Prolonged use of inhaled corticosteroids can suppress the hypothalamic-pituitary-adrenal (HPA) axis, leading to adrenal insufficiency.
- Beta-Agonist Use: Excessive use of LABAs may lead to increased asthma-related deaths; they should be used cautiously and as directed.
Interactions with Fluticasone Furoate-Vilanterol
Common Drug Interactions
- Drug Interactions: May interact with other medications, such as certain antifungals (e.g., ketoconazole) or other respiratory medications. Inform your healthcare provider about all medications you are taking.
- Food Interactions: No significant food interactions, but maintaining a balanced diet is encouraged for overall health.
Alternatives to Fluticasone Furoate-Vilanterol
- Other Inhaled Corticosteroids: Such as budesonide or beclomethasone.
- Other LABAs: Such as salmeterol, when used in combination with inhaled corticosteroids.
