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Flucelvax Quadrivalent
Flucelvax Quadrivalent is a cell culture-based inactivated influenza vaccine that provides protection against four strains of the influenza virus (two A strains and two B strains). Unlike traditional flu vaccines that are produced using eggs, Flucelvax is made using mammalian cell culture technology, making it suitable for individuals with egg allergies. It is used to help prevent the flu in both adults and children aged 6 months and older.
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Frequently Asked Questions
How is Flucelvax Quadrivalent different from traditional flu vaccines?
Flucelvax is produced using cell culture technology rather than eggs, making it suitable for individuals with egg allergies. This method also allows for quicker production and potentially improved protection.
Can I get the flu from Flucelvax Quadrivalent?
No, Flucelvax contains inactivated (killed) viruses, so it cannot cause the flu. Some people may experience mild side effects like soreness or fever, but these are normal immune responses.
How long does it take for Flucelvax to provide protection?
It typically takes about two weeks after vaccination for the body to develop sufficient immunity to protect against the flu.
Who should get Flucelvax Quadrivalent?
Flucelvax is recommended for adults and children 6 months and older as a preventive measure against the flu. It is especially important for high-risk groups, such as the elderly, young children, and those with chronic health conditions.
Is Flucelvax safe for individuals with egg allergies?
Yes, since Flucelvax is produced using mammalian cell culture technology rather than eggs, it is a good option for individuals with egg allergies. However, people with a history of severe allergic reactions to any vaccine component should consult their healthcare provider before receiving the vaccine.
Comprehensive Drug Guide
How Does Flucelvax Quadrivalent Work?
Flucelvax Quadrivalent contains inactivated (killed) influenza viruses that stimulate the immune system to produce antibodies. These antibodies provide protection against future infections by the same strains of the virus. By creating immunity to the included strains, the vaccine reduces the risk of contracting and spreading the flu, as well as decreasing the likelihood of complications.
Common Dosages
The standard dosage of Flucelvax Quadrivalent is:
- 0.5 mL administered as a single intramuscular (IM) injection, usually given once per flu season.
Typical Dosing
- For adults and children 6 months and older: One 0.5 mL intramuscular injection per flu season, administered in the upper arm (deltoid muscle) for adults or thigh for young children. For children aged 6 months to 8 years who have not previously been vaccinated, two doses are recommended, given at least four weeks apart.
Typical Dosing
FDA Approved Indications
- Active immunization against influenza in individuals 6 months of age and older.
- It is used to prevent flu-related complications, such as pneumonia, bronchitis, and other serious conditions, especially in high-risk populations like the elderly, young children, and those with chronic conditions.
Who Shouldn't Take Flucelvax Quadrivalent?
- Severe allergic reactions (e.g., anaphylaxis) to any components of the vaccine or following a previous dose of Flucelvax.
- Severe hypersensitivity to any ingredients in the vaccine formulation.
Advice From The Pharmacist
- Get vaccinated annually to ensure protection against the current strains of the flu virus, as they change each season.
- Flucelvax cannot cause the flu, as it contains inactivated viruses. However, mild side effects like soreness at the injection site, low-grade fever, or fatigue may occur as the immune system responds to the vaccine.
- Consult your healthcare provider if you have a history of severe allergic reactions to previous flu vaccines or vaccine components.
- Children aged 6 months to 8 years who are receiving the flu vaccine for the first time may require two doses. Speak with your healthcare provider for guidance on the appropriate dosing schedule.
- This vaccine is suitable for individuals with egg allergies, as it is made using mammalian cell culture rather than egg-based methods.
Side Effects of Flucelvax Quadrivalent
Common Side Effects
- Pain, redness, or swelling at the injection site
- Headache
- Fatigue
- Muscle aches
- Low-grade fever
Uncommon/Severe Side Effects
- Severe allergic reactions (anaphylaxis), including difficulty breathing, swelling of the face or throat, and hives.
- Guillain-Barré syndrome (GBS), though the risk is very low.
Risks and Warnings of Flucelvax Quadrivalent
- Allergic Reactions: Although rare, individuals who have had a severe allergic reaction to previous flu vaccines or any components of Flucelvax should not receive this vaccine.
- Guillain-Barré Syndrome (GBS): There is a very small risk of GBS associated with flu vaccines. If you have a history of GBS, discuss the risks and benefits of vaccination with your healthcare provider.
- Effectiveness: While Flucelvax significantly reduces the risk of contracting influenza, no vaccine provides 100% protection. Individuals should still practice flu prevention measures, such as frequent handwashing and avoiding contact with sick individuals.
Interactions with Flucelvax Quadrivalent
Common Drug Interactions
- Other vaccines: Flucelvax can be given simultaneously with other vaccines but should be administered at different injection sites.
- Immunosuppressive medications: Individuals taking medications that suppress the immune system may have a reduced immune response to the vaccine.
Alternatives to Flucelvax Quadrivalent
- Fluad Quadrivalent: An adjuvanted influenza vaccine recommended for individuals aged 65 and older, designed to boost the immune response in older adults.
- Fluzone High-Dose Quadrivalent: A high-dose flu vaccine that provides enhanced protection for older adults by delivering a higher concentration of antigens.
- Standard Egg-Based Flu Vaccines (e.g., Fluzone Quadrivalent): Another type of flu vaccine, though these are not recommended for individuals with severe egg allergies.
- Flublok Quadrivalent: A recombinant flu vaccine made without eggs or preservatives, suitable for individuals aged 18 and older.
