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Fleqsuvy

Fleqsuvy (baclofen oral suspension) is a muscle relaxant used to treat muscle spasms caused by conditions such as multiple sclerosis (MS) or spinal cord injury. It works by relaxing muscles and reducing muscle stiffness, pain, and spasms. Fleqsuvy is available as an oral suspension for patients who have difficulty swallowing tablets.



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Frequently Asked Questions

Can I stop taking Fleqsuvy suddenly?
Open FAQClose FAQ

No, stopping Fleqsuvy suddenly can lead to withdrawal symptoms such as hallucinations and seizures. Consult your doctor for a tapering schedule.

How long does it take for Fleqsuvy to work?
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Most patients begin to experience relief from muscle spasms within a few hours of taking Fleqsuvy.

Can Fleqsuvy be taken long-term?
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Yes, Fleqsuvy can be taken long-term to manage muscle spasticity, but regular monitoring by your healthcare provider is important.

Can I drive while taking Fleqsuvy?
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Fleqsuvy can cause drowsiness or dizziness, so avoid driving or operating heavy machinery until you know how it affects you.

What should I do if I miss a dose of Fleqsuvy?
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If you miss a dose of Fleqsuvy, take it as soon as you remember. If it’s close to your next dose, skip the missed dose and continue with your regular dosing schedule.

Comprehensive Drug Guide

How Does Fleqsuvy Work?

Fleqsuvy works by acting on the gamma-aminobutyric acid (GABA) receptors in the spinal cord, reducing the transmission of nerve signals that cause muscle spasms. This helps reduce muscle stiffness and improve mobility in patients with spasticity.



Common Dosages

  • Oral suspension: 25 mg/5 mL

Typical Dosing

  • The typical starting dose for Fleqsuvy is 5 mg three times daily, which can be increased gradually up to 80 mg per day as tolerated.



Typical Dosing

FDA Approved Indications

  • Treatment of muscle spasms and spasticity associated with multiple sclerosis and spinal cord injuries.


Who Shouldn't Take Fleqsuvy?

  • Known hypersensitivity to baclofen or any components of the formulation.


Advice From The Pharmacist

  • Shake the bottle of Fleqsuvy well before each use to ensure proper dosing.
  • Measure the dose using the provided oral syringe or a medication-measuring device, not a household spoon.
  • Do not stop taking Fleqsuvy suddenly, as this can cause withdrawal symptoms such as hallucinations or seizures.


Side Effects of Fleqsuvy

Common Side Effects

  • Drowsiness
  • Dizziness
  • Weakness


Uncommon/Severe Side Effects

  • Confusion
  • Hallucinations
  • Seizures


Risks and Warnings of Fleqsuvy

  • Withdrawal Symptoms: Abrupt discontinuation of Fleqsuvy can lead to severe withdrawal symptoms, including hallucinations and seizures. Tapering is necessary when discontinuing the drug.
  • CNS Depression: Fleqsuvy may cause central nervous system depression, leading to drowsiness, dizziness, and impaired motor coordination.


Interactions with Fleqsuvy

Common Drug Interactions

  • Alcohol: Increases the sedative effects of Fleqsuvy and should be avoided.
  • Benzodiazepines: Concurrent use may increase the risk of CNS depression.


Alternatives to Fleqsuvy

  • Lioresal (baclofen tablets)
  • Tizanidine (Zanaflex)