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Fioricet
Fioricet is a combination medication containing butalbital, acetaminophen, and caffeine used to treat tension headaches and migraine headaches. Butalbital is a barbiturate that helps to relax muscle contractions, acetaminophen is a pain reliever, and caffeine helps enhance the effects of acetaminophen by constricting blood vessels.
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Frequently Asked Questions
How quickly does Fioricet work?
Fioricet typically starts working within 30 to 60 minutes of taking a dose.
Can I take Fioricet for migraines?
While Fioricet is approved for tension headaches, it is sometimes used off-label for migraines. Consult your healthcare provider to see if it’s right for you.
Is Fioricet safe for long-term use?
Fioricet is not recommended for long-term use due to the risk of dependence and liver damage from acetaminophen. Use only as directed by your healthcare provider.
Can I take Fioricet with other pain relievers?
Avoid taking Fioricet with other acetaminophen-containing medications to prevent an overdose.
Does Fioricet cause drowsiness?
Yes, Fioricet can cause drowsiness and dizziness, so avoid driving or operating heavy machinery after taking it.
Comprehensive Drug Guide
How Does Fioricet Work?
Fioricet works by combining the muscle-relaxing effects of butalbital, the pain-relieving effects of acetaminophen, and the vasoconstrictive effects of caffeine to relieve tension headaches and migraines.
Common Dosages
- 50 mg butalbital / 300 mg acetaminophen / 40 mg caffeine per tablet or capsule
Typical Dosing
- The typical dosing is one to two tablets every 4 hours as needed, not exceeding 6 tablets per day.
Typical Dosing
FDA Approved Indications
- Tension headaches
- Migraine relief (off-label)
Who Shouldn't Take Fioricet?
- Liver disease (due to acetaminophen)
- History of substance abuse (due to butalbital)
Advice From The Pharmacist
- Do not exceed the recommended dose, as acetaminophen can cause liver damage.
- Fioricet can be habit-forming. Use only as directed and avoid prolonged use.
- Avoid alcohol while taking Fioricet, as it can increase the risk of liver damage and side effects from butalbital.
Side Effects of Fioricet
Common Side Effects
- Drowsiness
- Dizziness
- Lightheadedness
Uncommon/Severe Side Effects
- Liver damage (due to acetaminophen)
- Dependence or abuse (due to butalbital)
Risks and Warnings of Fioricet
- Liver Toxicity: Exceeding the recommended daily dose of acetaminophen can lead to serious liver damage. Do not combine Fioricet with other acetaminophen-containing products.
- Dependence: Butalbital is a barbiturate that can be habit-forming if taken for prolonged periods. Use only as prescribed.
Interactions with Fioricet
Common Drug Interactions
- Opioids: Combining Fioricet with opioids or other sedatives increases the risk of respiratory depression and sedation.
- Alcohol: Increases the risk of liver damage and central nervous system depression.
Alternatives to Fioricet
- Excedrin: An over-the-counter pain reliever containing aspirin, acetaminophen, and caffeine for tension headaches and migraines.
- Imitrex (sumatriptan): A prescription migraine medication that works by narrowing blood vessels.
- Midrin: A combination medication for tension and migraine headaches.
