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Evekeo ODT
Evekeo ODT (orally disintegrating tablets) is a stimulant medication containing amphetamine sulfate. It is primarily used to treat attention-deficit/hyperactivity disorder (ADHD) and narcolepsy. Evekeo ODT is also prescribed as part of a weight-loss treatment plan for patients who are obese and have not responded to other interventions. As a stimulant, it works by affecting chemicals in the brain that contribute to hyperactivity, focus, and impulse control.
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Frequently Asked Questions
How long does it take for Evekeo ODT to start working?
Evekeo ODT generally begins working within 30 to 60 minutes of taking a dose, with effects lasting for several hours.
Can Evekeo ODT be used long-term?
Evekeo ODT is often used for long-term treatment of ADHD and narcolepsy, but it requires regular monitoring due to its potential for abuse and side effects. Your doctor will regularly evaluate whether the benefits continue to outweigh the risks.
What should I do if I miss a dose of Evekeo ODT?
If you miss a dose, take it as soon as you remember, but avoid taking it too late in the day as it may cause insomnia. Do not double up on doses to make up for a missed dose.
Is Evekeo ODT safe for children?
Yes, Evekeo ODT is approved for use in children aged 3 years and older for the treatment of ADHD. However, it should be used under strict medical supervision, as it may cause growth suppression in children.
Can Evekeo ODT be taken with food?
Evekeo ODT can be taken with or without food, but avoid taking it with acidic beverages (such as orange juice) as they may reduce the effectiveness of the medication.
Comprehensive Drug Guide
How Does Evekeo ODT Work?
Evekeo ODT contains amphetamine, which works by increasing the levels of dopamine and norepinephrine in the brain. These neurotransmitters play a role in regulating attention, focus, and behavior. By enhancing the activity of these chemicals, Evekeo ODT helps improve concentration and reduces impulsive behavior in patients with ADHD and increases wakefulness in individuals with narcolepsy.
Common Dosages
- For ADHD: Starting dose is typically 5 mg once or twice daily, with potential adjustments based on response.
- For narcolepsy: Doses typically range from 5 mg to 60 mg daily, divided into smaller doses.
- For obesity: Typically 5 to 10 mg taken once daily in the morning.
Typical Dosing
FDA Approved Indications
- Attention-deficit/hyperactivity disorder (ADHD).
- Narcolepsy.
- Exogenous obesity: Short-term adjunct to weight-loss plans for individuals who are obese.
Who Shouldn't Take Evekeo ODT?
- Known hypersensitivity to amphetamines or any other ingredients in the formulation.
- Advanced arteriosclerosis, cardiovascular disease, or uncontrolled hypertension.
- Hyperthyroidism or glaucoma.
- History of drug abuse.
- Concurrent use of monoamine oxidase inhibitors (MAOIs) or within 14 days of stopping an MAOI.
Advice From The Pharmacist
- Take Evekeo ODT as directed, usually in the morning to avoid insomnia. If a second dose is prescribed, take it in the early afternoon to prevent sleep disturbances.
- Do not crush or chew the tablet; allow it to dissolve on the tongue without water.
- Evekeo ODT has a high potential for abuse. Keep the medication in a secure place to prevent misuse or abuse by others.
- Avoid drinking alcohol or using other stimulants while taking Evekeo ODT, as these substances can increase side effects or worsen certain conditions.
- If you experience any chest pain, shortness of breath, or hallucinations, contact your healthcare provider immediately.
Side Effects of Evekeo ODT
Common Side Effects
- Insomnia
- Dry mouth
- Loss of appetite
- Nervousness or anxiety
- Weight loss
- Stomach pain or nausea
Uncommon/Severe Side Effects
- Increased heart rate or high blood pressure
- Heart problems (chest pain, shortness of breath)
- Mental health changes (hallucinations, paranoia, mania)
- Severe allergic reactions (rash, swelling, difficulty breathing)
- Growth suppression in children
Risks and Warnings of Evekeo ODT
- Cardiovascular Risks: Evekeo ODT can increase heart rate and blood pressure. It should be used with caution in individuals with pre-existing heart conditions, and regular monitoring is recommended.
- Abuse Potential: Evekeo ODT is a Schedule II controlled substance with a high potential for abuse and dependence. Use should be carefully monitored, and long-term use is not recommended without regular evaluation by a healthcare provider.
- Mental Health Effects: In rare cases, Evekeo ODT may exacerbate psychiatric conditions like anxiety, depression, or bipolar disorder. Patients should be monitored for signs of mood changes or mental health issues.
Interactions with Evekeo ODT
Common Drug Interactions
- Monoamine oxidase inhibitors (MAOIs): Taking Evekeo ODT with or within 14 days of stopping an MAOI can lead to a hypertensive crisis (dangerously high blood pressure).
- Antidepressants: Some antidepressants, particularly those affecting serotonin, may increase the risk of serotonin syndrome when taken with Evekeo ODT.
- Antihypertensives: Amphetamines can reduce the effectiveness of blood pressure medications, requiring dose adjustments.
- Proton pump inhibitors (PPIs): May affect the absorption and effectiveness of Evekeo ODT.
Alternatives to Evekeo ODT
- Adderall (amphetamine-dextroamphetamine): Another stimulant used to treat ADHD and narcolepsy.
- Ritalin (methylphenidate): A commonly used stimulant for ADHD.
- Vyvanse (lisdexamfetamine): A stimulant medication often used for ADHD and binge eating disorder.
- Non-stimulant ADHD medications: Such as atomoxetine or guanfacine, which may be used in cases where stimulants are not appropriate.
