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Enstilar
Enstilar is a topical foam that combines calcipotriene (a vitamin D analog) and betamethasone dipropionate (a corticosteroid) to treat plaque psoriasis in adults. Enstilar helps reduce the severity of psoriasis by slowing down skin cell growth and reducing inflammation.
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Frequently Asked Questions
How quickly does Enstilar work?
Many patients notice improvement in their psoriasis symptoms within 1 to 2 weeks of using Enstilar.
Can I use Enstilar on my face?
No, Enstilar should not be applied to the face, groin, or underarms as the skin in these areas is more sensitive to corticosteroids.
How long can I use Enstilar?
Enstilar is typically used short-term to control flare-ups. Long-term use should be supervised by a healthcare provider due to the risk of adrenal suppression and other side effects.
Can Enstilar cause skin thinning?
Yes, long-term use of betamethasone, one of the active ingredients in Enstilar, can cause skin thinning, especially when applied over large areas of skin.
Is Enstilar covered by insurance?
Most insurance plans cover Enstilar, but coverage may vary. It’s a good idea to check with your provider about your specific plan’s coverage.
Comprehensive Drug Guide
How Does Enstilar Work?
Enstilar works through two active ingredients: calcipotriene, which slows skin cell overproduction, and betamethasone dipropionate, which reduces inflammation and redness. Together, they improve the symptoms of plaque psoriasis, such as scaling, itching, and thickened skin.
Common Dosages
- Enstilar is available as a foam containing calcipotriene 0.005% and betamethasone dipropionate 0.064%.
Typical Dosing
- Apply a thin layer of Enstilar foam to the affected skin areas once daily. The duration of use will depend on the severity of the condition and the response to treatment.
Typical Dosing
FDA Approved Indications
- Treatment of plaque psoriasis in adults
Who Shouldn't Take Enstilar?
- Known hypersensitivity to calcipotriene or betamethasone
- Patients with calcium metabolism disorders
Advice From The Pharmacist
- Shake the can of Enstilar well before use.
- Apply the foam to clean, dry skin and avoid covering the treated area with bandages unless instructed by your doctor.
- Avoid applying Enstilar to the face, groin, or underarms, as these areas are more sensitive to corticosteroids.
Side Effects of Enstilar
Common Side Effects
- Burning or stinging at the application site
- Dry skin
- Itching
Uncommon/Severe Side Effects
- Adrenal suppression (with long-term use)
- Skin thinning (with long-term use)
Risks and Warnings of Enstilar
- HPA Axis Suppression: Prolonged use of betamethasone may lead to adrenal suppression, especially if used over large areas of skin or under occlusion.
- Hypercalcemia: Calcipotriene can cause elevated calcium levels in the blood if used excessively.
Interactions with Enstilar
Common Drug Interactions
- Calcium supplements: May increase the risk of hypercalcemia when used in conjunction with calcipotriene.
- Other corticosteroids: Using multiple topical corticosteroids may increase the risk of side effects like skin thinning and adrenal suppression.
Alternatives to Enstilar
- Taclonex (calcipotriene/betamethasone ointment)
- Dovonex (calcipotriene topical solution)
- Clobex (clobetasol propionate)
