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EEMT HS
EEMT HS is a combination hormone replacement therapy that contains esterified estrogens and methyltestosterone. It is primarily used to manage symptoms associated with menopause, such as hot flashes, vaginal dryness, and other estrogen deficiency symptoms. Methyltestosterone, an androgen, is included to help address decreased libido and other symptoms caused by low testosterone levels in women. This therapy is typically prescribed for short-term use in postmenopausal women who need relief from both estrogen and androgen deficiencies.
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Frequently Asked Questions
How long should I take EEMT HS?
EEMT HS should be used for the shortest duration necessary to manage symptoms, typically no longer than a few years. Your healthcare provider will determine when it is safe to stop.
Can EEMT HS help with low libido?
Yes, the methyltestosterone component in EEMT HS is included to help address low libido and other androgen-deficiency symptoms in postmenopausal women.
What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember. If it is close to your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double up on doses.
Is EEMT HS safe for women with a history of breast cancer?
No, women with a history of breast cancer or other estrogen-sensitive cancers should not take EEMT HS, as it can increase the risk of cancer recurrence.
Can I take EEMT HS if I’m still menstruating?
EEMT HS is typically prescribed for postmenopausal women. If you are still menstruating, your healthcare provider will evaluate whether hormone therapy is appropriate for you.
Comprehensive Drug Guide
How Does EEMT HS Work?
EEMT HS works by supplementing the body with esterified estrogens to replace the natural estrogen that is decreased after menopause. Estrogens help alleviate menopausal symptoms by maintaining the health of the vaginal tissue, skin, and bones, while reducing hot flashes. Methyltestosterone is included to counteract the effects of low testosterone, improving libido, energy levels, and overall well-being in women experiencing androgen deficiency.
Common Dosages
- 1.25 mg esterified estrogens / 2.5 mg methyltestosterone
- 0.625 mg esterified estrogens / 1.25 mg methyltestosterone
Typical Dosing
- The usual dosage is one tablet taken at bedtime (HS).
- The dose may be adjusted by your healthcare provider based on symptom relief and tolerance, but the lowest effective dose should be used for the shortest duration possible to reduce risks.
Typical Dosing
FDA Approved Indications
- Treatment of moderate to severe menopausal symptoms, such as hot flashes, night sweats, and vaginal dryness.
- Hypoactive sexual desire disorder (HSDD) due to androgen deficiency in postmenopausal women.
Who Shouldn't Take EEMT HS?
- Known or suspected breast cancer or any other estrogen-dependent cancer
- Active or past history of thromboembolic disorders, such as deep vein thrombosis or pulmonary embolism
- Severe liver dysfunction
- Undiagnosed abnormal vaginal bleeding
- Pregnancy (category X)
Advice From The Pharmacist
- Take EEMT HS as prescribed, typically at bedtime, to help minimize side effects like nausea.
- Do not take this medication if you are pregnant or may become pregnant, as it can harm the fetus.
- Regularly monitor for symptoms of blood clots, such as leg pain, chest pain, or shortness of breath. If any of these occur, seek medical attention immediately.
- Avoid smoking, as it increases the risk of cardiovascular side effects while using hormone replacement therapy.
- Store the medication in a cool, dry place and keep it out of the reach of children.
Side Effects of EEMT HS
Common Side Effects
- Nausea or vomiting
- Breast tenderness or enlargement
- Changes in menstrual periods
- Headaches
- Acne or oily skin (due to testosterone component)
Uncommon/Severe Side Effects
- Blood clots (deep vein thrombosis or pulmonary embolism)
- Stroke or heart attack
- Liver problems, including jaundice (yellowing of the skin)
- Increased risk of breast cancer or other hormone-related cancers
Risks and Warnings of EEMT HS
- Cardiovascular Risks: Hormone replacement therapy, particularly with testosterone and estrogen, increases the risk of heart attack, stroke, and blood clots. This risk is higher in women who smoke or have preexisting cardiovascular conditions.
- Breast Cancer Risk: Long-term use of estrogen, with or without testosterone, can increase the risk of breast cancer. Regular mammograms and self-exams are recommended during treatment.
- Liver Toxicity: Methyltestosterone can be toxic to the liver with long-term use. Liver function should be monitored regularly while taking EEMT HS.
Interactions with EEMT HS
Common Drug Interactions
- Anticoagulants (blood thinners): EEMT HS may interfere with the effectiveness of blood thinners like warfarin, increasing the risk of blood clots.
- Corticosteroids: Taking EEMT HS with corticosteroids can increase the risk of fluid retention and other side effects.
- Cytochrome P450 inducers: Drugs like rifampin or carbamazepine can reduce the effectiveness of hormone replacement therapy by increasing metabolism of the hormones.
Alternatives to EEMT HS
- Estrogen-only therapy: For women who do not need androgen replacement, an estrogen-only therapy like Premarin or Estrace can be used to manage menopausal symptoms.
- Bioidentical hormones: Some women opt for bioidentical hormone replacement therapies, such as estradiol and micronized progesterone, which are said to mimic the body’s natural hormones.
- Non-hormonal options: For women who cannot take hormones, medications like gabapentin or venlafaxine can help manage menopausal symptoms.
