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EEMT

EEMT (Estrogens, Esterified-Methyltestosterone) is a combination hormone therapy used to treat symptoms of menopause, such as hot flashes, mood swings, and vaginal dryness. The drug contains esterified estrogens and methyltestosterone, which help balance hormone levels during menopause. It belongs to the classes of estrogens and androgens. This medication helps manage symptoms caused by declining levels of estrogen and testosterone in women going through menopause.



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Frequently Asked Questions

How long can I take EEMT?
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The duration of treatment should be as short as possible to manage menopausal symptoms. Regular follow-up with your doctor is important to evaluate the need for continued therapy.

Can EEMT cause weight gain?
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Some patients report weight gain while on EEMT, but it’s typically not a major side effect. Diet and exercise can help manage any changes in weight.

Does EEMT treat osteoporosis?
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EEMT is not specifically indicated for the prevention or treatment of osteoporosis, although estrogen can help maintain bone density.

Can I take EEMT if I’ve had breast cancer?
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No, EEMT is contraindicated in patients with a history of breast cancer due to the potential for hormone-sensitive cancer recurrence.

Do I need to have regular check-ups while on EEMT?
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Yes, regular check-ups, including blood pressure monitoring, breast exams, and pelvic exams, are essential while on hormone therapy.

Comprehensive Drug Guide

How Does EEMT Work?

EEMT works by supplementing the body’s decreased production of estrogen and testosterone during menopause. Estrogens help manage symptoms like hot flashes, night sweats, and vaginal dryness, while methyltestosterone helps improve energy levels, libido, and mood stability.



Common Dosages

  • Tablet form with esterified estrogens 1.25 mg and methyltestosterone 2.5 mg

Typical Dosing

  • For menopausal symptoms, the typical dosage is one tablet daily, which can be adjusted based on the patient’s response and tolerance.



Typical Dosing

FDA Approved Indications

  • Managing moderate to severe vasomotor symptoms of menopause (e.g., hot flashes)
  • Vulvar and vaginal atrophy associated with menopause
  • Low libido and fatigue during menopause


Who Shouldn't Take EEMT?

  • Known hypersensitivity to estrogens or methyltestosterone
  • Undiagnosed abnormal vaginal bleeding
  • History of breast or endometrial cancer
  • Liver disease


Advice From The Pharmacist

  • Take EEMT at the same time every day.
  • Do not skip doses as it may affect symptom control.
  • EEMT can increase the risk of cardiovascular issues, so regular check-ups are important.
  • Store the medication at room temperature.


Side Effects of EEMT

Common Side Effects

  • Nausea
  • Headache
  • Breast tenderness
  • Mood changes


Uncommon/Severe Side Effects

  • Blood clots
  • Heart attack or stroke
  • Breast cancer


Risks and Warnings of EEMT

  • Cardiovascular Risks: Hormone therapy, including EEMT, may increase the risk of heart attack, stroke, and blood clots, especially in smokers or those with a history of heart disease.
  • Cancer Risks: Long-term use of estrogens can increase the risk of breast and endometrial cancer. Regular monitoring is necessary.


Interactions with EEMT

Common Drug Interactions

  • Anticoagulants: May increase the risk of blood clots.
  • Corticosteroids: Can increase the effects of EEMT.
  • Avoid grapefruit juice, which can interfere with hormone metabolism.


Alternatives to EEMT

  • Premarin (conjugated estrogens)
  • Estrace (estradiol)
  • Activella (estradiol/norethindrone)
  • Bioidentical Hormone Replacement Therapy (BHRT)