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Edarbi
Edarbi (generic name: azilsartan medoxomil) is an angiotensin II receptor blocker (ARB) used to treat high blood pressure (hypertension). It works by relaxing blood vessels, which helps lower blood pressure and reduces the risk of complications like stroke, heart attack, and kidney damage. Edarbi is often prescribed when other antihypertensives are not effective or cause side effects.
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Frequently Asked Questions
How long does it take for Edarbi to lower blood pressure?
Most people see a significant reduction in blood pressure within 2 weeks of starting Edarbi, with full effects seen in 4-6 weeks.
Can I take Edarbi with other blood pressure medications?
Yes, Edarbi is often combined with other medications like diuretics or calcium channel blockers to achieve better blood pressure control.
Can I stop taking Edarbi once my blood pressure is controlled?
No, Edarbi is meant for long-term use to maintain blood pressure control. Stopping the medication abruptly can cause blood pressure to rise again.
Is Edarbi safe for people with kidney problems?
Edarbi should be used with caution in patients with kidney disease, and kidney function should be monitored regularly during treatment.
Can I take Edarbi if I’m pregnant?
No, Edarbi should not be used during pregnancy due to the risk of harm to the unborn baby. Contact your doctor immediately if you become pregnant while on this medication.
Comprehensive Drug Guide
How Does Edarbi Work?
Edarbi blocks the action of angiotensin II, a hormone that causes blood vessels to constrict. By preventing this action, Edarbi helps relax blood vessels, reducing blood pressure and making it easier for the heart to pump blood.
Common Dosages
- 40 mg tablets
- 80 mg tablets
Typical Dosing
- The usual starting dose of Edarbi is 40 mg once daily, which may be increased to 80 mg once daily if needed for better blood pressure control. The dose is usually adjusted based on the patient's response to the medication.
Typical Dosing
FDA Approved Indications
- Hypertension (high blood pressure)
Who Shouldn't Take Edarbi?
- Pregnancy, as it can cause injury or death to the developing fetus
- Severe liver or kidney impairment
- Known hypersensitivity to azilsartan or other ARBs
Advice From The Pharmacist
- Take Edarbi once daily at the same time, with or without food.
- It’s important to regularly monitor your blood pressure while taking Edarbi.
- If you become pregnant, stop taking Edarbi and contact your doctor immediately, as it can harm the unborn baby.
- Avoid using potassium supplements or salt substitutes containing potassium unless your doctor advises otherwise.
Side Effects of Edarbi
Common Side Effects
- Dizziness
- Fatigue
- Diarrhea
Uncommon/Severe Side Effects
- Low blood pressure (hypotension)
- Kidney problems
- Hyperkalemia (high potassium levels)
Risks and Warnings of Edarbi
- Pregnancy Risk: Edarbi should not be used during pregnancy, especially in the second and third trimesters, as it can harm the fetus.
- Kidney Function: Edarbi may affect kidney function, especially in individuals with pre-existing kidney disease. Regular kidney function monitoring is recommended.
- Hyperkalemia: Edarbi can increase potassium levels, especially when taken with potassium supplements or other medications that raise potassium levels.
Interactions with Edarbi
Common Drug Interactions
- Potassium supplements: Can increase the risk of hyperkalemia when taken with Edarbi.
- NSAIDs: Nonsteroidal anti-inflammatory drugs like ibuprofen may reduce the effectiveness of Edarbi and increase the risk of kidney problems.
- Diuretics: Combining Edarbi with diuretics may lead to excessive blood pressure reduction.
Alternatives to Edarbi
- Losartan (Cozaar): Another ARB used to treat high blood pressure and protect the kidneys in diabetic patients.
- Valsartan (Diovan): An ARB used to treat high blood pressure and heart failure.
- Amlodipine: A calcium channel blocker used for high blood pressure control, often combined with ARBs.