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Diovan
Diovan, the brand name for valsartan, is an angiotensin II receptor blocker (ARB) primarily prescribed to treat high blood pressure (hypertension) and heart failure. It may also be used after a heart attack to help the heart function better. Valsartan works by relaxing blood vessels so that blood can flow more easily, helping to lower blood pressure and reduce the strain on the heart. This medication is part of the ARB drug class, which is known for its ability to prevent blood vessel constriction and improve overall cardiovascular health.
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Frequently Asked Questions
What should I do if I miss a dose of valsartan?
Take it as soon as you remember, but skip it if it’s close to your next dose. Do not double the dose to catch up.
Can I take valsartan with food?
Yes, valsartan can be taken with or without food. However, taking it consistently in the same manner each day is recommended.
How long does it take for valsartan to work?
It may take a few weeks to see the full effects on blood pressure, but you may notice some improvements within the first week.
Can I drink alcohol while taking valsartan?
It’s best to limit alcohol consumption, as it can increase the risk of side effects like dizziness or low blood pressure.
Can valsartan cause weight gain?
Weight gain is not a common side effect of valsartan, but if you notice significant changes in your weight, consult your healthcare provider.
Comprehensive Drug Guide
How Does Diovan Work?
Valsartan works by blocking the effects of a substance in the body called angiotensin II, which typically causes blood vessels to constrict. By blocking angiotensin II, valsartan allows the blood vessels to relax and widen, making it easier for blood to flow. This reduces blood pressure and decreases the workload on the heart, which helps manage conditions like hypertension and heart failure.
Common Dosages
Valsartan is available in the following common strengths: 40 mg, 80 mg, 160 mg, and 320 mg tablets. Your healthcare provider will determine the best dosage based on your condition and response to the treatment.
Typical Dosing
For adults:
- Hypertension: Typically, the starting dose is 80 mg to 160 mg once daily, with a maximum dose of 320 mg per day.
- Heart Failure: The recommended starting dose is 40 mg twice daily, with adjustments based on tolerance.
- Post-Heart Attack: The usual starting dose is 20 mg twice daily, gradually increased as needed.
Dosing for children is determined by the doctor based on weight and age.
Typical Dosing
FDA Approved Indications
- Treating high blood pressure (hypertension)
- Managing heart failure
- Improving survival following a heart attack
Off-Label Uses
Off-label uses may include treating kidney disease in patients with diabetes and preventing strokes in people with high blood pressure.
Who Shouldn't Take Diovan?
- Pregnancy (especially in the second and third trimesters)
- Severe kidney disease
- A history of allergic reactions to valsartan or any other ARB
- Patients with a condition called bilateral renal artery stenosis
Advice From The Pharmacist
- Take valsartan exactly as prescribed, with or without food, but at the same time each day.
- Avoid using salt substitutes or potassium supplements unless advised by your doctor, as valsartan can increase potassium levels in your body.
- Be cautious with alcohol, as it may increase the risk of dizziness or fainting.
- If you miss a dose, take it as soon as you remember, but skip it if it's close to your next dose.
- Always consult your healthcare provider if you experience persistent side effects or have concerns about your medication.
Side Effects of Diovan
Common Side Effects
- Dizziness or lightheadedness
- Fatigue
- Low blood pressure (hypotension)
Uncommon/Severe Side Effects
- Fainting
- Swelling (especially in the face, lips, or throat)
- Kidney problems (indicated by changes in urination)
Risks and Warnings of Diovan
- Pregnant women should not take valsartan, as it can harm an unborn baby, especially in the second and third trimesters.
- People with severe kidney disease or those taking medications that increase potassium levels should use this drug with caution.
- Regular monitoring of blood pressure and kidney function is recommended during treatment.
Interactions with Diovan
Common Drug Interactions
- Other blood pressure medications, such as ACE inhibitors or diuretics
- Potassium supplements or salt substitutes
- Nonsteroidal anti-inflammatory drugs (NSAIDs), which can reduce its effectiveness
Alternatives to Diovan
- Losartan (another ARB)
- Lisinopril (an ACE inhibitor)
- Amlodipine (a calcium channel blocker)
- Hydrochlorothiazide (a diuretic)
