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Drospiren-Eth Estrad-Levomefol
Drospirenone-Ethinyl Estradiol-Levomefolate is a combination oral contraceptive used primarily for birth control. It contains drospirenone (a progestin), ethinyl estradiol (an estrogen), and levomefolate calcium (a form of folic acid). This medication not only prevents pregnancy but also helps to reduce the risk of neural tube defects in case pregnancy occurs. It can also be used to manage premenstrual dysphoric disorder (PMDD) and acne in women seeking contraception.
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Frequently Asked Questions
Can Drospirenone-Ethinyl Estradiol-Levomefolate be used to treat acne?
Yes, this combination birth control is FDA-approved for treating moderate acne in women who also seek contraception.
What should I do if I miss a pill?
If you miss one pill, take it as soon as you remember and continue with your regular schedule. If you miss two or more pills, use a backup form of contraception for the next 7 days.
Does Drospirenone-Ethinyl Estradiol-Levomefolate protect against sexually transmitted infections (STIs)?
No, this medication does not protect against STIs. Use condoms or other barrier methods to reduce the risk of infections.
Is it safe to take this medication if I have high blood pressure?
Women with uncontrolled hypertension should avoid this contraceptive, as it may increase the risk of cardiovascular events. If you have controlled hypertension, consult with your healthcare provider for personalized advice.
What should I do if I experience signs of a blood clot?
If you notice symptoms like leg pain, swelling, chest pain, or shortness of breath, seek medical attention immediately, as these may be signs of a blood clot or other serious complications.
Comprehensive Drug Guide
How Does Drospiren-Eth Estrad-Levomefol Work?
This contraceptive prevents pregnancy by combining drospirenone (a synthetic progestin) and ethinyl estradiol (a synthetic estrogen) to inhibit ovulation. It also thickens cervical mucus to block sperm from reaching the egg and thins the uterine lining, making it harder for a fertilized egg to implant. The levomefolate component ensures that adequate folic acid is available, reducing the risk of birth defects should pregnancy occur.
Common Dosages
Each pill pack typically contains:
- 24 active pills with 3 mg drospirenone, 0.02 mg ethinyl estradiol, and 0.451 mg levomefolate calcium.
- 4 inactive pills containing only levomefolate calcium.
Typical Dosing
- Take one active pill daily for 24 consecutive days, followed by one inactive pill for 4 days, then start a new pack.
- Pills should be taken at the same time every day for maximum effectiveness. There is no break between packs.
Typical Dosing
FDA Approved Indications
- Prevention of pregnancy (birth control)
- Treatment of moderate acne in women seeking contraception
- Premenstrual dysphoric disorder (PMDD) management
- Folate supplementation to prevent neural tube defects
Who Shouldn't Take Drospiren-Eth Estrad-Levomefol?
- History of blood clots, deep vein thrombosis (DVT), or pulmonary embolism
- History of stroke or heart attack
- Uncontrolled hypertension
- Liver disease
- Known or suspected breast cancer
- Women over 35 years old who smoke
Advice From The Pharmacist
- Take the pill at the same time every day to maintain consistent hormone levels and reduce the risk of pregnancy.
- If you miss a dose, take it as soon as you remember. If you miss two or more pills, use a backup method of contraception, such as condoms, for the next 7 days.
- This medication can increase potassium levels, so be cautious if you are on potassium-sparing diuretics or have kidney issues.
- Store the pills in a cool, dry place, and always keep them out of reach of children.
Side Effects of Drospiren-Eth Estrad-Levomefol
Common Side Effects
- Nausea or vomiting
- Breast tenderness
- Headaches or migraines
- Weight gain or bloating
- Mood changes
Uncommon/Severe Side Effects
- Blood clots (deep vein thrombosis or pulmonary embolism)
- Stroke or heart attack, particularly in women over 35 who smoke
- Liver problems or jaundice (yellowing of the skin)
- Severe allergic reactions
Risks and Warnings of Drospiren-Eth Estrad-Levomefol
- Cardiovascular Risk: Women who smoke and are over the age of 35 are at a higher risk of serious cardiovascular events, including heart attack, stroke, and blood clots. Smoking cessation is strongly recommended.
- Blood Clot Risk: Hormonal contraceptives, particularly those containing drospirenone, carry a higher risk of blood clots than other types of birth control. Monitor for signs of DVT, such as leg pain or swelling.
- Hyperkalemia: Drospirenone has the potential to increase potassium levels. Women with kidney, liver, or adrenal disease should be cautious and may require regular potassium level monitoring.
Interactions with Drospiren-Eth Estrad-Levomefol
Common Drug Interactions
- Antibiotics: Certain antibiotics (such as rifampin) may decrease the effectiveness of this birth control, increasing the risk of pregnancy.
- Anticonvulsants: Medications like phenytoin and carbamazepine can reduce the effectiveness of oral contraceptives.
- Potassium-sparing diuretics: Medications like spironolactone may increase the risk of hyperkalemia (high potassium levels).
- NSAIDs: Long-term use of NSAIDs may also elevate potassium levels.
Alternatives to Drospiren-Eth Estrad-Levomefol
- Combination Oral Contraceptives: Other options like Yaz or Ortho Tri-Cyclen offer different hormone dosages and may be suitable alternatives.
- Progestin-only pills (mini pills): Suitable for women who cannot take estrogen-based contraceptives.
- Non-hormonal birth control: Such as the copper IUD (Paragard) or barrier methods like condoms or diaphragms.
- Other folate-supplemented contraceptives: Beyaz is another birth control option that contains both hormones and folate.
