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Diphen
Diphen is a brand-name medication that contains diphenhydramine, an antihistamine used to treat allergy symptoms such as runny nose, sneezing, itchy eyes, and rashes. It is also used to treat motion sickness, insomnia, and cough. As a first-generation antihistamine, Diphen has sedative effects and is often used as a short-term sleep aid.
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Frequently Asked Questions
How long does it take for Diphen to work?
Diphen usually starts working within 30 minutes of administration.
Can I take Diphen for insomnia long-term?
It is not recommended to take Diphen long-term for sleep. Consult your doctor if you have chronic sleep problems.
Is Diphen safe for children?
Diphen is safe for children over the age of 6 in age-appropriate doses. Consult a pediatrician before administering it to younger children.
Can I take Diphen with alcohol?
No, combining Diphen with alcohol can increase the sedative effects and cause excessive drowsiness.
What should I do if I miss a dose of Diphen?
If you miss a dose, take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose. Do not double the dose to catch up.
Comprehensive Drug Guide
How Does Diphen Work?
Diphen works by blocking histamine receptors in the body, reducing the effects of histamine, which causes allergic reactions. Its ability to cross the blood-brain barrier also leads to sedative effects, making it effective as a sleep aid. Additionally, Diphen has anticholinergic properties that help reduce cough and nausea associated with motion sickness.
What is Diphen Used For?
- Allergic rhinitis (hay fever)
- Cold symptoms
- Motion sickness
- Insomnia (short-term)
- Cough relief
Common Dosages
Diphen is available in the following forms and strengths:
- Tablets: 25 mg, 50 mg
- Liquid form: 12.5 mg/5 mL
- Topical creams: 1% or 2% for skin allergies
Typical Dosing
FDA Approved Indications
- For allergies: 25-50 mg every 4-6 hours as needed.
- For motion sickness: 25-50 mg taken 30 minutes before exposure to motion, then every 4-6 hours.
- For insomnia: 50 mg at bedtime.
Who Shouldn't Take Diphen?
Diphen should not be used in individuals with:
- Known hypersensitivity to diphenhydramine or its components
- Severe breathing problems (e.g., emphysema, asthma)
- Glaucoma
- Urinary retention
Advice From The Pharmacist
- Avoid driving or operating heavy machinery after taking Diphen, as it can cause drowsiness.
- Do not take Diphen with other antihistamines or sedatives unless advised by a healthcare provider.
- Diphen can cause dry mouth, so drink plenty of water and consider using sugar-free lozenges to relieve symptoms.
Side Effects of Diphen
Common Side Effects
- Drowsiness
- Dizziness
- Dry mouth, nose, or throat
- Blurred vision
Uncommon/Severe Side Effects
- Confusion, especially in older adults
- Difficulty urinating
- Fast or irregular heartbeat
- Severe allergic reactions (rash, difficulty breathing)
Risks and Warnings of Diphen
Sedation Risk: Diphen can cause significant drowsiness, especially in combination with alcohol or other sedatives.
Elderly Use: Older adults are more prone to confusion and dizziness when taking Diphen.
Anticholinergic Effects: Long-term use can cause dry mouth, constipation, and urinary retention.
Interactions with Diphen
Common Drug Interactions
- CNS depressants: Combining Diphen with alcohol, sedatives, or tranquilizers can increase drowsiness.
- MAO inhibitors: Avoid using Diphen with monoamine oxidase inhibitors (MAOIs), as this may lead to serious drug interactions.
Alternatives to Diphen
- Loratadine (Claritin): A non-drowsy antihistamine used for allergies.
- Cetirizine HCl (Zyrtec): A second-generation antihistamine with less sedative effects.
- Meclizine: An alternative antihistamine for motion sickness that causes less drowsiness.
