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Diethylpropion HCl ER
Diethylpropion HCl ER (extended-release) is a sympathomimetic amine used as an appetite suppressant for the short-term management of obesity. It is prescribed to individuals who are significantly overweight and helps to promote weight loss by reducing hunger, making it easier for patients to follow a calorie-reduced diet. Diethylpropion HCl ER is typically used as part of a comprehensive weight-loss program that includes exercise and behavior modification.
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Frequently Asked Questions
How quickly does Diethylpropion HCl ER start working?
Diethylpropion HCl ER typically begins to suppress appetite within 1 to 2 hours after taking the medication.
Is Diethylpropion HCl ER safe for long-term use?
No, Diethylpropion HCl ER is prescribed for short-term use only, usually for a period of a few weeks. Prolonged use is not recommended due to the risk of tolerance and dependence.
What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember, unless it’s close to your next scheduled dose. Do not double the dose to make up for the missed one.
Can Diethylpropion HCl ER be taken with other weight loss medications?
It is not recommended to combine Diethylpropion with other weight loss medications unless specifically instructed by your healthcare provider, as this may increase the risk of serious side effects.
Is Diethylpropion HCl ER safe during pregnancy?
Diethylpropion HCl ER is not recommended during pregnancy due to potential risks to the developing fetus. Consult your healthcare provider if you are pregnant or planning to become pregnant.
Comprehensive Drug Guide
How Does Diethylpropion HCl ER Work?
Diethylpropion HCl ER works by stimulating the central nervous system (CNS), particularly by increasing the levels of norepinephrine in the brain, which suppresses appetite. This stimulation reduces hunger signals, helping patients reduce their food intake and aiding in weight loss efforts.
What is Diethylpropion HCl ER Used For?
- Short-term treatment of obesity, in combination with a calorie-reduced diet and physical activity.
Common Dosages
Diethylpropion HCl ER is available in:
- 75 mg extended-release tablets
Typical Dosing
FDA Approved Indications
- The typical dose is 75 mg taken once daily, usually in the morning. The extended-release formulation ensures a steady release of the medication throughout the day, reducing appetite.
Who Shouldn't Take Diethylpropion HCl ER?
Diethylpropion HCl ER should not be used in individuals with:
- Severe hypertension
- Advanced arteriosclerosis
- Hyperthyroidism
- Glaucoma
- History of drug abuse
- Severe cardiovascular disease
- Known hypersensitivity to sympathomimetic amines
Advice From The Pharmacist
- Take Diethylpropion HCl ER as prescribed, usually in the morning, to reduce the risk of insomnia. Avoid taking it in the late afternoon or evening.
- Diethylpropion HCl ER is intended for short-term use (typically a few weeks). Prolonged use may lead to tolerance, reducing its effectiveness.
- Do not increase the dose or take it more frequently than prescribed, as this increases the risk of side effects, including dependence.
- It is important to combine Diethylpropion with a healthy diet and exercise regimen for the best weight loss results.
Side Effects of Diethylpropion HCl ER
Common Side Effects
- Dry mouth
- Insomnia
- Increased heart rate
- Nervousness or restlessness
- Constipation
Uncommon/Severe Side Effects
- Chest pain or heart palpitations
- Shortness of breath
- Severe mood changes (e.g., anxiety, depression, aggression)
- Elevated blood pressure
Risks and Warnings of Diethylpropion HCl ER
Cardiovascular Risk: Diethylpropion can increase blood pressure and heart rate, which may elevate the risk of cardiovascular events such as heart attack or stroke, particularly in individuals with pre-existing heart conditions.
Abuse Potential: As a Schedule IV controlled substance, Diethylpropion has the potential for abuse. Patients with a history of drug or alcohol abuse should use caution.
Tolerance: Over time, the body may build a tolerance to Diethylpropion, reducing its effectiveness. Do not increase the dose without consulting your healthcare provider.
Interactions with Diethylpropion HCl ER
Common Drug Interactions
- MAO inhibitors: Combining Diethylpropion with monoamine oxidase inhibitors (e.g., phenelzine) can lead to dangerous increases in blood pressure.
- Other stimulants: Using Diethylpropion with other stimulant medications can increase the risk of overstimulation, nervousness, and elevated blood pressure.
- Antihypertensive medications: Diethylpropion may reduce the effectiveness of medications used to lower blood pressure.
Alternatives to Diethylpropion HCl ER
- Phentermine: Another appetite suppressant used for short-term weight loss management.
- Liraglutide (Saxenda): A medication used to control appetite and promote weight loss by mimicking a hormone that helps regulate hunger.
- Orlistat (Alli, Xenical): A weight-loss medication that works by blocking the absorption of fat in the digestive system.
- Bupropion-Naltrexone (Contrave): A combination drug used for weight management by affecting appetite and reward centers in the brain.
