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Diethylpropion HCl
Diethylpropion HCl is a stimulant medication used as a short-term treatment for obesity. It works by suppressing appetite, helping patients reduce caloric intake and aiding in weight loss efforts when combined with diet and exercise. Diethylpropion is typically prescribed for patients with a body mass index (BMI) of 30 or higher or for those with a BMI of 27 or higher who also have weight-related conditions such as diabetes or high blood pressure.
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Frequently Asked Questions
How quickly does Diethylpropion HCl start working?
Diethylpropion HCl typically begins to suppress appetite within 1 to 2 hours of taking the medication.
Can Diethylpropion HCl be taken long-term?
Diethylpropion HCl is usually prescribed for short-term use (up to 12 weeks). Long-term use is not recommended due to the risk of tolerance, dependence, and side effects.
What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember, unless it’s close to your next scheduled dose. Do not double the dose to make up for a missed one.
Can Diethylpropion HCl be taken with other weight loss medications?
It is not recommended to combine Diethylpropion with other weight loss medications unless specifically directed by your healthcare provider, as this may increase the risk of serious side effects.
Is Diethylpropion safe during pregnancy?
Diethylpropion is not recommended during pregnancy due to the potential risk to the developing fetus. Always consult your healthcare provider if you are pregnant or planning to become pregnant while taking this medication.
Comprehensive Drug Guide
How Does Diethylpropion HCl Work?
Diethylpropion works by stimulating the central nervous system (CNS), increasing the levels of neurotransmitters such as norepinephrine, which suppresses appetite. By reducing hunger signals, diethylpropion helps patients reduce food intake, promoting weight loss in combination with lifestyle modifications.
What is Diethylpropion HCl Used For?
- Short-term management of obesity, in combination with a calorie-reduced diet and exercise.
Common Dosages
Diethylpropion HCl is available in the following forms:
- Immediate-release tablets: 25 mg
- Extended-release tablets: 75 mg
Typical Dosing
FDA Approved Indications
- For immediate-release tablets, the typical dose is 25 mg taken three times daily before meals.
- For extended-release tablets, the dose is 75 mg once daily, typically taken in the morning to avoid insomnia.
Who Shouldn't Take Diethylpropion HCl?
Diethylpropion HCl should not be used in individuals with:
- Severe hypertension
- Advanced arteriosclerosis
- Hyperthyroidism
- Glaucoma
- History of drug abuse
- Known hypersensitivity to sympathomimetic amines
Advice From The Pharmacist
- Take Diethylpropion HCl as directed, typically 30 to 60 minutes before meals for the immediate-release form. The extended-release form is taken once in the morning.
- Avoid taking the medication late in the day, as it can cause insomnia.
- Diethylpropion HCl is intended for short-term use (a few weeks), and its effectiveness may diminish over time. Do not increase the dose or duration of use without consulting your healthcare provider.
- Combine the medication with a low-calorie diet and exercise for the best results.
Side Effects of Diethylpropion HCl
Common Side Effects
- Insomnia
- Nervousness or restlessness
- Dry mouth
- Increased heart rate
- Constipation
Uncommon/Severe Side Effects
- Elevated blood pressure
- Heart palpitations
- Chest pain
- Shortness of breath
- Mood changes (e.g., depression or aggression)
Risks and Warnings of Diethylpropion HCl
Cardiovascular Risk: Diethylpropion can increase heart rate and blood pressure, which may elevate the risk of cardiovascular events such as heart attack or stroke, especially in patients with a history of heart disease.
Abuse and Dependence: Diethylpropion has a potential for abuse due to its stimulant effects. Patients with a history of substance abuse should avoid using this medication.
Tolerance: The effectiveness of Diethylpropion may decrease with prolonged use, and taking higher doses to compensate can lead to serious health risks.
Interactions with Diethylpropion HCl
Common Drug Interactions
- MAO inhibitors: Combining Diethylpropion with monoamine oxidase inhibitors (e.g., phenelzine) can cause dangerous increases in blood pressure.
- Other stimulants: Using Diethylpropion with other stimulant medications can increase the risk of side effects such as elevated heart rate and blood pressure.
- Antihypertensives: Diethylpropion may reduce the effectiveness of medications used to lower blood pressure.
Alternatives to Diethylpropion HCl
- Phentermine: Another appetite suppressant used for short-term weight management.
- Orlistat (Alli, Xenical): A weight loss medication that works by reducing fat absorption in the intestines.
- Liraglutide (Saxenda): An injectable medication used to promote weight loss by controlling appetite.
- Bupropion-Naltrexone (Contrave): A combination medication used for weight loss by targeting appetite and reward centers in the brain.
