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Dichlorphenamide
Dichlorphenamide is a type of medication called a carbonic anhydrase inhibitor. It is used to treat a rare genetic disorder called periodic paralysis, where the patient suffers from occasional episodes of muscle weakness or paralysis. The common side effects can include a loss of appetite, a metallic taste in the mouth, and feeling tired. Your healthcare provider will weigh the benefits against these potential issues.
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Frequently Asked Questions
Can I drink alcohol while taking Dichlorphenamide?
It's best to avoid alcohol while on dichlorphenamide as it can worsen certain side effects such as dizziness and confusion.
I feel dizzy or drowsy after taking Dichlorphenamide, is that normal?
Yes, dizziness and drowsiness are common side effects. If these symptoms persist or worsen, consult your doctor.
What should I do if I miss a dose of Dichlorphenamide?
If it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
Comprehensive Drug Guide
How Does Dichlorphenamide Work?
Dichlorphenamide is a carbonic anhydrase inhibitor. It works by decreasing the buildup of body fluids (edema) caused by congestive heart failure or certain medications. It could also decrease a third space accumulation of body fluids due to primary kidney disease.
What is Dichlorphenamide Used For?
FDA indications: Dichlorphenamide is primarily used to treat periodic paralysis, which causes occasional episodes of extreme muscle weakness or not being able to move at all.
Offlabel uses: There are no known offlabel uses
Common Dosages
Tablets: 50mg
Typical Dosing
FDA Approved Indications
- Primary periodic paralysis: The initial recommended dosage is 50 mg twice daily. Dosage can be adjusted based on the individual patient's response to therapy.
Who Shouldn't Take Dichlorphenamide?
- Those who have severe kidney disease, liver disease, or certain types of eye problems (high level of Chloride in Cornea and Lens).
- Those with low levels of potassium (hypokalemia) or sodium (hyponatremia) in the blood.
- Those who are allergic to dichlorphenamide or other sulfonamides.
- Those who have adrenal gland problems (e.g., Addision's disease).
- Pregnant or planning to get pregnant, as the effects of dichlorphenamide on pregnancy are unknown.
Advice From The Pharmacist
- Take this medication with food if it upsets your stomach.
- Drink enough liquids while on this medication unless instructed to do otherwise.
- It is advised to avoid activities requiring mental clarity such as driving, until your body adjusts to the medication.
- This medicine could cause dizziness or vision problems. It can also increase your risk of falling.
- Do not stop taking dichlorphenamide suddenly without talking to your doctor.
- Regular checkups are necessary for monitoring progress and potential side effects.
Side Effects of Dichlorphenamide
Common Side Effects
- Loss of appetite
- Nausea
- Vomiting
- Feeling tired
Uncommon/Severe Side Effects
- Uncommon side effects:
- Decreased sensation to touch
- Discomfort in the chest
- Rare side effects:
- You might have muscle cramps or spasms
- Confusion
- Dizziness
- Severe side effects:
- Fast or irregular heartbeat
- Shortness of breath
- Swelling of feet or lower legs
- Unusual tiredness or weakness
Risks and Warnings of Dichlorphenamide
- May cause serious allergic reactions including anaphylaxis and severe rash.
- Blood disorders have been reported in patients treated with carbonic anhydrase inhibitors.
- May cause serious side effects like changes in the level of red or white blood cells.
- Should use caution in patients with a history of kidney stones.
- It may also make your skin sensitive to sunlight.
- Interactions
Interactions with Dichlorphenamide
Common Drug Interactions
- High doses of aspirin
- Corticosteroids
- Primidone
Alternatives to Dichlorphenamide
- Acetazolamide
- Methazolamide