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Dibenzyline
Dibenzyline is a type of medication known as an alphaadrenergic blocker that is used primarily to manage pheochromocytoma, a tumor of the adrenal glands, before surgery. It works by relaxing and widening blood vessels so blood can flow more easily, reducing the severity of symptoms caused by the tumor. Some common side effects include stuffy nose, dry mouth, and tiredness, but your doctor will usually ensure the benefits outweigh these issues.
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Frequently Asked Questions
Can I instantly stop taking Dibenzyline once my symptoms are gone?
No, always consult your doctor before changing the course or cessation of the medication.
Can I take Dibenzyline if I have kidney disease?
You should consult your doctor before taking Dibenzyline if you have kidney disease as it might need a dose adjustment.
Can I take Dibenzyline if I'm pregnant?
It's best to consult your healthcare provider in this case as there may be risks associated with Dibenzyline use during pregnancy.
Does Dibenzyline make me feel dizzy?
Yes, dizziness is one of the common side effects of Dibenzyline. Ensure to rise slowly from a sitting or lying position to avoid sudden changes in blood pressure.
Does Dibenzyline make you feel dizzy?
Yes, Dibenzyline can cause dizziness. Avoid activities like driving until you know how this medication affects you.
I forgot to take my Dibenzyline dose, what should I do?
If it's close to the time of your next dose, skip the missed dose and continue your regular dosing schedule. Do not double the dose to make up for the missed one. If it's still a considerable amount of time until your next dose, take the missed dose as soon as you remember.
What if I miss a dose of Dibenzyline?
If it's close to your next dose, skip the missed one, else take it as soon as you remember, but never double up doses!
Comprehensive Drug Guide
How Does Dibenzyline Work?
Dibenzyline is an alphaadrenergic blocker that prevents the alphareceptors in your blood vessels from receiving signals that cause vasoconstriction. This leads to vasodilation, or a widening of blood vessels, reducing blood pressure and improving blood flow.
What is Dibenzyline Used For?
FDA indications: Primarily for pheochromocytoma to lower blood pressure and reduce symptoms before surgery. It's also used for peripheral vascular disease and sweating associated with pheochromocytoma.
Offlabel uses: It can be used for Raynaud's Disease and autonomic dysfunction.
Common Dosages
Tablets: 10mg
Typical Dosing
FDA Approved Indications
- Start with an initial dose of 10mg two to three times per day. Gradually increase the dose up to a maximum of 1mg/kg daily.
Off-Label Uses
- Dosing varies based on the severity of the condition and will be determined by the healthcare provider.
Who Shouldn't Take Dibenzyline?
- Those allergic to phenoxybenzamine.
- Patients with coronary artery disease.
- Individuals with a history of kidney disease.
- Patients who are pregnant or breastfeeding (unless the benefits outweigh the risks).
- Patients with a history of stroke.
Advice From The Pharmacist
- Dibenzyline may cause dizziness upon standing up. Take it slow when getting up from a sitting or lying position.
- It's advisable to avoid driving or operating machinery until you know how Dibenzyline affects you.
- You might feel dryness in your mouth. Chewing sugarfree gum or sipping water regularly might help.
- Take the medication exactly as prescribed, and ensure not to miss a dose.
- Prioritize consulting your doctor if you are planning surgery, including a dental procedure.
- Report any new or unusual symptoms to your healthcare provider promptly.
Side Effects of Dibenzyline
Common Side Effects
- Stuffy nose.
- Dry mouth.
- Drowsiness and fatigue.
Uncommon/Severe Side Effects
- Uncommon side effects:
- Headaches.
- Blurred vision.
- Rapid heart rate.
- Rare side effects:
- Difficulty urinating.
- Swelling in the legs.
- Weight gain.
Risks and Warnings of Dibenzyline
- Risks associated with Dibenzyline include low blood pressure, which can lead to fainting and injury. You should be cautious when getting up after sitting or lying down.
- This medication can affect your ability to operate machinery or drive.
- If you're pregnant or trying to become pregnant, talk to your healthcare provider, as this medication could potentially harm a developing baby.
- Longterm use of Dibenzyline can result in tolerance, reducing its effectiveness over time.
Interactions with Dibenzyline
Common Drug Interactions
- Betablockers
- Heart rhythm medications
- Antidepressants
- Diuretics
Alternatives to Dibenzyline
- Prazosin
- Terazosin
- Doxazosin
