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Dexycu
Dexycu (dexamethasone intraocular suspension) is a corticosteroid medication used to treat postoperative inflammation following eye surgery, such as cataract surgery. It helps reduce swelling, pain, and inflammation by suppressing the immune system’s response in the eye. Dexycu is a long-acting, sustained-release corticosteroid administered as a single injection into the eye during surgery.
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Frequently Asked Questions
How long does Dexycu last after surgery?
Dexycu is designed to provide up to 30 days of sustained anti-inflammatory action with a single dose administered during surgery.
Can Dexycu cause an increase in eye pressure?
Yes, Dexycu may cause a temporary rise in intraocular pressure. Your eye doctor will monitor your eye pressure during follow-up visits.
What should I do if I experience vision changes after receiving Dexycu?
If you notice any significant changes in your vision, such as blurred vision, eye pain, or redness, contact your healthcare provider immediately.
Can Dexycu be used in people with glaucoma?
Caution is required when using Dexycu in individuals with glaucoma, as it may temporarily raise intraocular pressure. Your doctor will evaluate the risks and benefits before administering Dexycu.
How is Dexycu different from steroid eye drops?
Dexycu is a long-acting injectable corticosteroid that provides a sustained release of medication over several weeks. Unlike eye drops, it requires only one administration during surgery and eliminates the need for daily dosing.
Comprehensive Drug Guide
How Does Dexycu Work?
Dexycu works by reducing inflammation through its action as a corticosteroid, which suppresses the immune response and decreases the production of substances that cause inflammation in the eye after surgery. This helps promote healing and reduces the risk of postoperative complications.
Common Dosages
- Intraocular suspension: 9% dexamethasone, administered as a single dose of 0.005 mL into the posterior chamber of the eye during surgery.
Typical Dosing
- Dexycu is administered as a single injection during eye surgery to help control inflammation for up to 30 days after surgery. No additional doses are required.
Typical Dosing
FDA Approved Indications
- Postoperative inflammation following ocular surgery, including cataract surgery.
Who Shouldn't Take Dexycu?
- Known hypersensitivity to dexamethasone or any component of the formulation.
- Active eye infections, including viral, bacterial, or fungal infections of the eye.
Advice From The Pharmacist
- Dexycu is given as a single injection during eye surgery, so no further doses or eye drops are typically needed to control inflammation.
- If you experience symptoms such as increased eye pain, vision changes, or redness, contact your ophthalmologist immediately, as these could be signs of complications.
- Follow all postoperative care instructions provided by your surgeon to ensure proper healing.
Side Effects of Dexycu
Common Side Effects
- Increased intraocular pressure (temporary rise in pressure inside the eye)
- Eye pain
- Blurry vision
- Redness or swelling in the eye
Uncommon/Severe Side Effects
- Infection in the eye
- Cataract formation
- Glaucoma
Risks and Warnings of Dexycu
- Increased Intraocular Pressure: Dexycu can cause a temporary increase in eye pressure, which may lead to glaucoma or vision problems if not monitored.
- Infection Risk: Corticosteroids like Dexycu may increase the risk of developing eye infections, particularly if there is an existing infection.
- Cataract Formation: Long-term use of corticosteroids in the eye can contribute to the development of cataracts, although this is less common with a single dose.
Interactions with Dexycu
Common Drug Interactions
- Other corticosteroids: Using multiple corticosteroids may increase the risk of systemic side effects or excessive suppression of the immune response.
- Nonsteroidal anti-inflammatory drugs (NSAIDs): Combining Dexycu with NSAIDs may increase the risk of eye complications, such as delayed healing or corneal ulcers.
Alternatives to Dexycu
- Durezol (difluprednate): Another corticosteroid used for the treatment of postoperative inflammation following ocular surgery, typically administered as eye drops.
- Prednisolone acetate: A commonly used corticosteroid eye drop for reducing inflammation after eye surgery.
- Lotemax (loteprednol etabonate): A corticosteroid eye drop used to manage inflammation and pain following eye surgery.
