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Dextenza
Dextenza (generic name: dexamethasone ophthalmic insert) is a corticosteroid used to treat ocular inflammation and pain following eye surgery. Dextenza is a sustained-release insert that is placed into the lower tear duct, where it slowly releases dexamethasone over time to reduce inflammation, swelling, and discomfort. This insert provides targeted, long-lasting relief without the need for daily eye drops.
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Frequently Asked Questions
How long does Dextenza last in the eye?
Dextenza provides continuous release of dexamethasone for up to 30 days after being placed in the tear duct.
Can I wear contact lenses after Dextenza is inserted?
Your doctor may recommend avoiding contact lenses while the Dextenza insert is in place to prevent discomfort and ensure proper healing.
What should I do if I feel discomfort after Dextenza is inserted?
Some mild discomfort or irritation is normal, but if it persists or worsens, contact your eye doctor to ensure the insert is positioned correctly or to rule out infection.
How is Dextenza different from eye drops?
Dextenza provides long-lasting relief with a single insertion, eliminating the need for frequent administration of corticosteroid eye drops after surgery.
Is Dextenza safe for children?
Dextenza has been approved for use in adults. Its safety and efficacy in pediatric patients have not been fully established.
Comprehensive Drug Guide
How Does Dextenza Work?
Dextenza works by slowly releasing dexamethasone, a potent corticosteroid, into the eye. Dexamethasone reduces inflammation by inhibiting the release of inflammatory mediators, such as prostaglandins, and decreasing the accumulation of inflammatory cells. This helps control pain, swelling, and redness after eye surgery.
Common Dosages
- Dextenza is available as a 0.4 mg dexamethasone insert that is placed into the tear duct by a healthcare professional.
Typical Dosing
- For postoperative inflammation and pain: One Dextenza insert (0.4 mg dexamethasone) is placed into the lower tear duct of the eye after surgery. The insert provides continuous release of the medication for up to 30 days.
Typical Dosing
FDA Approved Indications
- Ocular inflammation and pain following ophthalmic surgery
Who Shouldn't Take Dextenza?
- Active ocular infections, including viral, fungal, or bacterial eye infections
- Known hypersensitivity to dexamethasone or any of the insert components
Advice From The Pharmacist
- Dextenza is inserted by your eye doctor after surgery and slowly dissolves over time, so there is no need for daily application or removal.
- You should avoid rubbing your eyes after the insert is placed, as this can dislodge it.
- Contact your healthcare provider if you experience any symptoms of eye infection, such as increased redness, swelling, or discharge.
Side Effects of Dextenza
Common Side Effects
- Eye irritation or discomfort
- Increased tear production
- Foreign body sensation in the eye
Uncommon/Severe Side Effects
- Increased intraocular pressure (glaucoma)
- Infection or delayed healing after surgery
Risks and Warnings of Dextenza
- Increased Intraocular Pressure: As with other corticosteroids, Dextenza can cause an increase in eye pressure, which may lead to glaucoma. Regular monitoring by your eye doctor is important.
- Infection Risk: Corticosteroids like dexamethasone can increase the risk of infections, especially after eye surgery. Signs of infection should be promptly reported to your healthcare provider.
Interactions with Dextenza
Common Drug Interactions
- Other corticosteroid treatments: Combining Dextenza with other corticosteroids may increase the risk of side effects, such as increased intraocular pressure or delayed healing.
- Antibiotic eye drops: These may be used concurrently with Dextenza to prevent or treat infections after surgery.
Alternatives to Dextenza
- Loteprednol ophthalmic drops (Lotemax): Another corticosteroid eye drop commonly used for eye inflammation after surgery.
- Fluorometholone ophthalmic drops: A mild corticosteroid eye drop used for similar purposes.
- Prednisolone ophthalmic drops: A corticosteroid eye drop used to manage postoperative eye inflammation.
