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DayVigo
DayVigo (generic name: lemborexant) is a prescription medication used to treat insomnia, specifically difficulties with falling asleep and staying asleep. It belongs to a newer class of medications called dual orexin receptor antagonists, which work by blocking the activity of the neuropeptides orexin A and orexin B that promote wakefulness. By inhibiting orexin, DayVigo helps regulate sleep patterns and improve overall sleep quality.
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Frequently Asked Questions
How long does it take for DayVigo to work?
DayVigo starts working within 30 minutes to 1 hour after taking the dose. It is best taken immediately before bed.
Can I take DayVigo every night?
Yes, DayVigo can be taken every night as prescribed. However, it should only be used when you have at least 7 hours of sleep time available.
What should I do if I miss a dose?
If you miss a dose of DayVigo, do not take it if it is already late in the night or close to waking up. Skip the missed dose and take it at your next bedtime.
Can DayVigo cause dependence?
DayVigo has a lower potential for abuse and dependence compared to other sleep medications, but it is still classified as a Schedule IV controlled substance due to some risk.
Is DayVigo safe for long-term use?
Yes, DayVigo is generally safe for long-term use when taken as prescribed. However, regular monitoring by your healthcare provider is important to assess its ongoing effectiveness and safety.
Comprehensive Drug Guide
How Does DayVigo Work?
DayVigo works by blocking orexin receptors (OX1R and OX2R) in the brain, which reduces the effects of the wake-promoting neuropeptides orexin A and B. This helps promote sleep by decreasing the signals that keep individuals awake, allowing for easier sleep initiation and maintenance.
Common Dosages
- 5 mg tablets
- 10 mg tablets
Typical Dosing
- For insomnia: The recommended starting dose is 5 mg once daily, taken right before bedtime. The dose may be increased to 10 mg if needed, depending on the individual's response and tolerance. DayVigo should only be taken when there are at least 7 hours remaining before the planned time of waking.
Typical Dosing
FDA Approved Indications
- Insomnia, characterized by difficulties with sleep onset and/or sleep maintenance
Who Shouldn't Take DayVigo?
- Narcolepsy
- Known hypersensitivity to lemborexant or any other ingredients in the formulation
Advice From The Pharmacist
- Take DayVigo right before going to bed. Ensure that you have enough time for a full night’s sleep (at least 7 hours).
- Avoid consuming alcohol while taking DayVigo, as it may increase the risk of side effects like drowsiness or dizziness.
- Do not drive or engage in activities requiring full alertness after taking DayVigo, as it can cause next-day drowsiness.
Side Effects of DayVigo
Common Side Effects
- Drowsiness
- Headache
- Dizziness
Uncommon/Severe Side Effects
- Sleep paralysis
- Complex sleep behaviors (e.g., sleepwalking)
- Impaired next-day functioning
Risks and Warnings of DayVigo
- Next-Day Impairment: DayVigo may cause next-day drowsiness or impaired alertness, even when taken as directed. Avoid driving or operating heavy machinery the next day if you feel drowsy.
- Complex Sleep Behaviors: DayVigo has been associated with sleepwalking, sleep driving, and other activities while not fully awake. Discontinue the medication if these occur.
Interactions with DayVigo
Common Drug Interactions
- CYP3A inhibitors: Drugs like ketoconazole may increase the levels of DayVigo in the blood, leading to a higher risk of side effects.
- CYP3A inducers: Medications like rifampin may decrease the effectiveness of DayVigo.
- CNS depressants: Combining DayVigo with alcohol, opioids, or other sedatives may increase the risk of excessive drowsiness.
Alternatives to DayVigo
- Ambien (zolpidem): A commonly used sedative for insomnia with similar sleep-promoting effects.
- Lunesta (eszopiclone): Another sedative used to treat difficulties with falling and staying asleep.
- Belsomra (suvorexant): Another dual orexin receptor antagonist used for insomnia.
