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Daytrana
Daytrana (methylphenidate transdermal system) is a central nervous system (CNS) stimulant used to treat attention deficit hyperactivity disorder (ADHD) in children and adolescents. It is designed as a transdermal patch that delivers methylphenidate, a stimulant that helps improve focus, attention, and impulse control by increasing levels of certain neurotransmitters in the brain.
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Frequently Asked Questions
How long does it take for Daytrana to start working?
Daytrana starts working within 1 to 2 hours of application, and its effects last throughout the day. The patch should be removed after 9 hours of wear.
Can Daytrana be used in adults?
Daytrana is approved for use in children aged 6 to 17 years. It is not typically prescribed for adults, but your healthcare provider may recommend other stimulant medications for adult ADHD.
What should I do if my child forgets to wear the Daytrana patch?
If the patch is forgotten, apply it as soon as possible, but remove it at the usual time to maintain the 9-hour wear time. Do not extend the wear time to make up for the missed application.
Can Daytrana cause growth problems in children?
Yes, stimulants like Daytrana can cause growth suppression in some children. Height and weight should be monitored regularly, and your healthcare provider may adjust the dose if needed.
Is Daytrana safe for long-term use?
Yes, Daytrana is generally safe for long-term use when monitored by a healthcare provider. Regular check-ups are important to monitor growth, heart health, and mental well-being.
Comprehensive Drug Guide
How Does Daytrana Work?
Daytrana works by increasing levels of dopamine and norepinephrine in the brain, neurotransmitters that play key roles in attention, focus, and impulse control. The transdermal delivery system allows for the controlled release of methylphenidate over time, helping to improve symptoms of ADHD.
Common Dosages
- Transdermal patches: 10 mg, 15 mg, 20 mg, 30 mg (doses are based on patch strength).
Typical Dosing
- The recommended starting dose for Daytrana is a 10 mg patch, applied once daily for 9 hours. The dose may be adjusted based on the patient's response and tolerability, up to a maximum of 30 mg daily.
Typical Dosing
FDA Approved Indications
- Attention deficit hyperactivity disorder (ADHD) in children aged 6 to 17 years.
Who Shouldn't Take Daytrana?
- Known hypersensitivity to methylphenidate or any component of the patch.
- Glaucoma.
- Severe anxiety, tension, or agitation.
- Tics or Tourette’s syndrome.
Advice From The Pharmacist
- Apply the Daytrana patch to a clean, dry area of skin on the hip. Rotate application sites daily to prevent skin irritation.
- The patch should be worn for 9 hours and then removed. Effects may last for several hours after the patch is removed.
- Avoid exposing the patch to heat (e.g., heating pads, hot tubs), as this may increase the rate of drug absorption and lead to overdose.
Side Effects of Daytrana
Common Side Effects
- Decreased appetite
- Trouble sleeping (insomnia)
- Headache
- Irritability
- Skin redness or irritation at the application site
Uncommon/Severe Side Effects
- Heart problems (increased heart rate, chest pain)
- High blood pressure
- Psychiatric symptoms (agitation, hallucinations, suicidal thoughts)
- Growth suppression in children
Risks and Warnings of Daytrana
- Cardiovascular Risk: Stimulants like Daytrana can increase heart rate and blood pressure. Patients with a history of heart problems or hypertension should be monitored closely.
- Abuse Potential: Daytrana is a Schedule II controlled substance with a high potential for abuse and dependence. It should be used only as prescribed.
- Psychiatric Symptoms: Stimulants can exacerbate symptoms of anxiety, psychosis, or mania in individuals with pre-existing mental health conditions.
Interactions with Daytrana
Common Drug Interactions
- Monoamine oxidase inhibitors (MAOIs): Combining Daytrana with MAOIs can cause a dangerous increase in blood pressure. MAOIs should be discontinued at least 14 days before starting Daytrana.
- Antihypertensive medications: Stimulants like Daytrana can reduce the effectiveness of medications used to lower blood pressure.
- Other stimulants: Combining Daytrana with other CNS stimulants (e.g., amphetamines) increases the risk of side effects like high blood pressure and heart problems.
Alternatives to Daytrana
- Concerta (methylphenidate ER): An extended-release oral form of methylphenidate for the treatment of ADHD.
- Adderall XR (amphetamine/dextroamphetamine ER): A long-acting stimulant used to treat ADHD in children and adults.
- Vyvanse (lisdexamfetamine): Another long-acting stimulant used to treat ADHD and binge-eating disorder.
