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Dantrium
Dantrium (Dantrolene) is a medication designed to relieve muscle tightness and cramping caused by certain neurological disorders such as multiple sclerosis, cerebral palsy, stroke, and injury to the spine. Its common side effects include nausea, vomiting, diarrhea, and weakness, but your healthcare provider will always weigh these issues before prescribing.
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Frequently Asked Questions
Can I take Dantrium if I am pregnant?
Consult your healthcare provider if you are pregnant or planning to become pregnant. The effects of Dantrium on the fetus are not clear.
Does Dantrium cause drowsiness?
Yes, Dantrium can cause drowsiness and dizziness. It's advised not to drive or use machinery until you are sure you can perform such activities safely.
I missed a dose of Dantrium, what should I do?
If it's close to your next dose, skip the missed one and continue with your regular schedule. If there's plenty of time before your next dose, take the missed one as soon as you remember. However, it never doubles the dose.
Comprehensive Drug Guide
How Does Dantrium Work?
Dantrium is a directacting skeletal muscle relaxant. It acts by inhibiting the release of calcium ions in the skeletal muscle, thereby reducing the intensity of muscle contractions and alleviating muscle spasms.
What is Dantrium Used For?
FDA indications: Dantrium is commonly used to treat muscle spasms and tightness in people with neurological disorders such as multiple sclerosis, cerebral palsy, or stroke.
Offlabel uses: While primarily used for treating spasticity, Dantrium may also be used offlabel to manage malignant hyperthermia, a lifethreatening reaction to certain drugs used during general anesthesia.
Common Dosages
Capsules: 25mg, 50mg, 100mg
Typical Dosing
FDA Approved Indications
- Muscle spasms: The starting dose is 25mg per day, gradually increasing to 100mg per day.
Off-Label Uses
- Malignant hyperthermia: Dosing is determined by the healthcare provider based on individual health conditions.
Who Shouldn't Take Dantrium?
- Individuals allergic to Dantrium or any of its components.
- People having active liver disease.
- Women who are pregnant or breastfeeding (due to unknown effects on the fetus or baby).
- Patients with lung or breathing problems.
- Individuals with heart diseases.
Advice From The Pharmacist
- Dantrium should be taken by mouth with a full glass of water.
- This medication should be taken as directed by your healthcare provider, generally once daily initially, followed by a gradual increase in dosage.
- Dantrium can affect liver function; thus, regular liver tests are recommended.
- It might also cause drowsiness, dizziness, or lightheadedness. Do not drive, use machinery, or do anything that requires alertness until you can do it safely.
- Avoid alcoholic beverages as they can exacerbate these effects.
- Lastly, consult your physician promptly if you notice dark urine, persistent nausea or vomiting, stomach or abdominal pain, or yellowing eyes or skin.
Side Effects of Dantrium
Common Side Effects
- You might feel nauseous or have vomiting or diarrhea.
- You might feel weak or fatigued.
- Dizziness and lightheadedness are also common.
Uncommon/Severe Side Effects
- Rare side effects:
- You might get a sunburn easily.
- You might have trouble sleeping.
- You might notice changes in your vision.
- Severe side effects:
- You might start having allergic reactions, including itchiness, rash, or swelling of the face/tongue/throat.
- Seek immediate medical attention if you experience severe dizziness, changes in the amount of urine, or signs of liver disease such as yellowing eyes/skin and dark urine.
Risks and Warnings of Dantrium
- Individuals with liver diseases or a history of liver diseases should avoid Dantrium as it can cause liver damage.
- Pregnant or breastfeeding women should consult a healthcare provider before taking Dantrium as it may cause harm to the baby.
- Be cautious if you have any heart diseases or lung or breathing problems ? Dantrium can potentially compound these issues.
- Dantrium can cause drowsiness and dizziness, so avoid driving or any other activity that requires concentration until you are sure you can perform such activities safely.
Interactions with Dantrium
Common Drug Interactions
- CNS depressants
- Sedatives
- Alcohol
- Estrogens
Alternatives to Dantrium
- Baclofen
- Tizanidine
- Diazepam
- Clonazepam
- Gabapentin
