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Cycloset
Cycloset (generic name: bromocriptine mesylate) is an oral dopamine receptor agonist used to treat type 2 diabetes. It works by improving blood sugar control in adults, often used alongside diet and exercise to manage blood glucose levels. Cycloset is also used to treat conditions like Parkinson’s disease and hyperprolactinemia, though these indications are separate from its use in diabetes.
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Frequently Asked Questions
How quickly does Cycloset start working?
Cycloset typically starts lowering blood sugar levels within 2 hours of taking the medication, with full effects noticeable after several weeks of regular use.
Can Cycloset cause low blood sugar?
When used alone, Cycloset has a low risk of causing low blood sugar. However, the risk increases when taken with other diabetes medications like insulin or sulfonylureas.
Can I take Cycloset at night?
No, Cycloset should be taken in the morning, ideally within two hours of waking up, as it works by regulating the body's morning metabolism.
What should I do if I miss a dose of Cycloset?
If you miss a dose, take it the next morning. Do not double up on doses to make up for a missed one.
Is Cycloset safe for long-term use?
Yes, Cycloset is generally safe for long-term use when taken as prescribed, but regular monitoring of your blood sugar levels and overall health is important.
Comprehensive Drug Guide
How Does Cycloset Work?
Cycloset works by activating dopamine receptors in the brain, which plays a role in regulating metabolism and insulin sensitivity. This helps improve the body's ability to control blood sugar levels, particularly in the morning, when blood sugar levels tend to spike in individuals with type 2 diabetes.
Common Dosages
- 0.8 mg tablets
Typical Dosing
- The typical starting dose for managing type 2 diabetes is 0.8 mg taken once daily in the morning within 2 hours of waking. The dose may be gradually increased by your healthcare provider based on response, up to a maximum of 4.8 mg per day.
Typical Dosing
FDA Approved Indications
- Type 2 diabetes, to improve blood sugar control in adults alongside diet and exercise.
Who Shouldn't Take Cycloset?
- Known hypersensitivity to bromocriptine or any other components of the formulation
- Uncontrolled hypertension
- A history of syncopal (fainting) migraines
Advice From The Pharmacist
- Take Cycloset in the morning, ideally within two hours of waking up, to maximize its effects on blood sugar control.
- Do not take more than prescribed, as this can increase the risk of side effects.
- Cycloset may cause dizziness or lightheadedness, especially when first starting the medication or increasing the dose. Be cautious when standing up suddenly.
Side Effects of Cycloset
Common Side Effects
- Nausea
- Fatigue
- Dizziness or lightheadedness
- Headache
Uncommon/Severe Side Effects
- Orthostatic hypotension (a drop in blood pressure upon standing)
- Hallucinations or confusion
Risks and Warnings of Cycloset
- Low Blood Pressure: Cycloset can cause orthostatic hypotension, especially when standing up quickly. Be cautious and rise slowly from sitting or lying down.
- Psychiatric Effects: Bromocriptine, the active ingredient in Cycloset, may cause psychiatric side effects such as hallucinations or confusion, particularly in higher doses.
Interactions with Cycloset
Common Drug Interactions
- Antipsychotic medications: These may decrease the effectiveness of Cycloset, as they block dopamine receptors.
- Other diabetes medications: When used with other diabetes drugs like insulin or sulfonylureas, Cycloset may increase the risk of low blood sugar (hypoglycemia).
- Ergot alkaloids: Concurrent use of ergot alkaloids (e.g., for migraines) may increase the risk of side effects like high blood pressure.
Alternatives to Cycloset
- Metformin: A first-line oral medication for type 2 diabetes that helps reduce blood sugar production in the liver.
- GLP-1 receptor agonists (e.g., liraglutide): Injectable medications that help regulate blood sugar and promote weight loss.
- SGLT2 inhibitors (e.g., canagliflozin): Medications that help the kidneys remove excess glucose from the blood.
