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Cyclafem 1/35

Cyclafem 1/35 is a combination oral contraceptive pill containing ethinyl estradiol (an estrogen) and norethindrone (a progestin). It is primarily used to prevent pregnancy by inhibiting ovulation, thickening cervical mucus, and altering the uterine lining to make it more difficult for sperm to reach an egg or for a fertilized egg to attach. Cyclafem 1/35 can also be prescribed to regulate menstrual cycles, reduce the risk of ovarian cysts, and treat acne in women who desire birth control.



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Frequently Asked Questions

What should I do if I miss a pill?
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If you miss one active pill, take it as soon as you remember, then take the next pill at your usual time. If you miss two or more active pills, follow the instructions on the package insert or consult your doctor.

Does Cyclafem 1/35 protect against STIs?
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No, Cyclafem 1/35 does not protect against sexually transmitted infections. Use condoms or another barrier method to reduce the risk of STIs.

Can I take Cyclafem 1/35 if I’m breastfeeding?
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Cyclafem 1/35 is generally not recommended for breastfeeding women, as it may reduce milk production. Consult your doctor for alternative contraceptive options while breastfeeding.

What should I do if I experience nausea while taking Cyclafem 1/35?
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Nausea is a common side effect. Try taking the pill with food or at bedtime to minimize nausea. If nausea persists, consult your healthcare provider.

When should I stop taking Cyclafem 1/35?
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You can stop taking Cyclafem 1/35 if you wish to become pregnant or if directed by your healthcare provider. If you are switching to another form of contraception, ask your doctor for guidance on how to transition safely.

Comprehensive Drug Guide

How Does Cyclafem 1/35 Work?

Cyclafem 1/35 works by:

  • Inhibiting ovulation through the combined actions of ethinyl estradiol and norethindrone.
  • Thickening cervical mucus, making it more difficult for sperm to reach the uterus.
  • Altering the uterine lining, making it less favorable for the implantation of a fertilized egg.

What is Cyclafem 1/35 Used For?

  • Prevention of pregnancy
  • Regulation of menstrual cycles
  • Treatment of moderate acne in women who also desire contraception

Common Dosages

Cyclafem 1/35 is available by prescription as a 28-day oral contraceptive pack. It is not classified as a controlled substance.

  • Active pills: 21 white tablets containing 1 mg of norethindrone and 0.035 mg of ethinyl estradiol.
  • Inactive pills: 7 green placebo tablets taken during the last week of the cycle.


Typical Dosing

FDA Approved Indications

Take one active tablet daily for 21 days, followed by one inactive tablet daily for the next 7 days. This regimen is repeated each month. To maximize effectiveness, take the pill at the same time every day.


Who Shouldn't Take Cyclafem 1/35?

Cyclafem 1/35 should not be used in individuals with:

  • A history of blood clots, stroke, or heart attack
  • Uncontrolled hypertension
  • Known or suspected breast cancer
  • Liver disease or liver tumors
  • Known hypersensitivity to ethinyl estradiol, norethindrone, or any component of the formulation


Advice From The Pharmacist

  • Take the pill at the same time every day to maintain consistent hormone levels and maximize pregnancy prevention.
  • If you miss a dose, follow the instructions on the package insert or consult your healthcare provider for guidance on how to proceed.
  • Use an additional form of contraception, such as condoms, if you miss two or more active pills in a row.
  • Store Cyclafem 1/35 at room temperature and keep it away from moisture.
  • Cyclafem 1/35 does not protect against sexually transmitted infections (STIs). Use a barrier method for STI prevention.

Side Effects of Cyclafem 1/35

Common Side Effects

  • Nausea
  • Breast tenderness
  • Headache
  • Weight gain
  • Mood changes


Uncommon/Severe Side Effects

  • Blood clots
  • Stroke
  • Heart attack
  • Liver problems (e.g., jaundice)


Risks and Warnings of Cyclafem 1/35

Blood Clots: Cyclafem 1/35 may increase the risk of blood clots, especially in women who smoke or are over the age of 35. Women with a history of clotting disorders should avoid using this medication.

Cardiovascular Risks: Women with pre-existing heart conditions or high blood pressure should use this medication with caution, as it may increase the risk of heart attack or stroke.

Breast Cancer: Hormonal contraceptives may slightly increase the risk of breast cancer, especially in women with a family history or personal history of the disease.

Interactions with Cyclafem 1/35

Common Drug Interactions

  • Antibiotics: Some antibiotics, such as rifampin, may reduce the effectiveness of Cyclafem 1/35.
  • Anticonvulsants: Medications like phenytoin and carbamazepine may decrease the effectiveness of this contraceptive.
  • St. John’s Wort: This herbal supplement may lower the effectiveness of hormonal birth control.

Alternatives to Cyclafem 1/35

  • Ortho-Novum 1/35: A similar estrogen-progestin combination pill with the same hormone concentrations.
  • Loestrin Fe: Another combination oral contraceptive with different hormone levels.
  • Depo-Provera: A long-acting injectable contraceptive option for women who prefer not to take daily pills.