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Cortane-B

Cortane-B is a combination medication used to treat inflammatory and allergic conditions of the ear. It contains hydrocortisone (a corticosteroid), pramoxine (a local anesthetic), and chloroxylenol (an antibacterial). Cortane-B is commonly prescribed to reduce itching, swelling, and discomfort in cases of ear infections and inflammation, such as otitis externa (swimmer’s ear). The hydrocortisone reduces inflammation, pramoxine provides pain relief, and chloroxylenol acts as an antiseptic to prevent or treat bacterial infections.

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Frequently Asked Questions

How long does it take for Cortane-B to work?
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Most patients experience relief from symptoms within a few days of starting treatment, but full resolution may take up to 7 to 10 days.

Can I use Cortane-B if I have a perforated eardrum?
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No, Cortane-B should not be used if you have a perforated eardrum. Consult your healthcare provider for alternative treatments.

What should I do if I miss a dose?
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If you miss a dose, use it as soon as you remember. If it's close to your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double up on doses.

Is it safe to use Cortane-B during pregnancy?
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There is limited data on the safety of Cortane-B during pregnancy. Consult your healthcare provider if you are pregnant or planning to become pregnant while using this medication.

Can I use Cortane-B for other ear infections?
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Cortane-B is specifically indicated for conditions like otitis externa. It should not be used for inner ear infections (otitis media) or infections caused by viruses or fungi unless prescribed by a healthcare provider.

Comprehensive Drug Guide

How Does Cortane-B Work?

Cortane-B works by combining the effects of its three active ingredients:

  • Hydrocortisone reduces inflammation by suppressing the immune response and decreasing the production of inflammatory chemicals.
  • Pramoxine numbs the affected area, providing relief from pain and itching.
  • Chloroxylenol helps eliminate bacteria, preventing or treating bacterial infections in the ear.


What is Cortane-B Used For?

Cortane-B is FDA-approved for the treatment of:

  • Otitis externa (swimmer's ear)
  • Allergic or inflammatory conditions of the ear
  • Itching, redness, and swelling due to ear infections


Common Dosages

Cortane-B is available by prescription in the form of otic (ear) drops. It is not classified as a controlled substance.

  • Typically comes in a solution that is applied directly into the ear canal.


Typical Dosing

FDA Approved Indications

For otitis externa or ear inflammation: Apply the prescribed number of drops (usually 3 to 5 drops) into the affected ear 2 to 4 times a day, as directed by a healthcare provider.

Who Shouldn't Take Cortane-B?

Cortane-B should not be used in individuals with:

  • Perforated eardrum
  • Hypersensitivity to hydrocortisone, pramoxine, chloroxylenol, or any other ingredients in the formulation
  • Viral or fungal ear infections


Advice From The Pharmacist

  • Warm the bottle by holding it in your hand for a few minutes before administering the drops to reduce discomfort when applied.
  • Lie down or tilt your head when applying the drops, and keep the affected ear facing upward for a few minutes after administering the drops.
  • Avoid contaminating the dropper by touching it to any surfaces, including your ear.
  • Use the medication for the full duration prescribed, even if symptoms improve.


Side Effects of Cortane-B

Common Side Effects

  • Mild stinging or burning sensation when the drops are applied
  • Temporary ear discomfort


Uncommon/Severe Side Effects

  • Allergic reactions, such as rash, itching, or swelling
  • Severe irritation or infection of the ear


Risks and Warnings of Cortane-B

Perforated Eardrum: Cortane-B should not be used if there is a perforated eardrum, as the ingredients may cause further damage or lead to more serious infections.

Prolonged Use: Prolonged use of corticosteroids in the ear can increase the risk of thinning the ear canal skin or secondary infections.

Allergic Reactions: Discontinue use if signs of allergic reactions occur, such as rash, itching, or swelling.a

Interactions with Cortane-B

Common Drug Interactions

Cortane-B has limited systemic absorption, so interactions with other medications are rare. However, it is important to inform your healthcare provider of all medications and supplements you are using to avoid potential interactions.



Alternatives to Cortane-B

  • Ciprodex (ciprofloxacin and dexamethasone): An antibiotic and corticosteroid combination used for similar ear conditions.
  • Cortisporin Otic (neomycin, polymyxin B, and hydrocortisone): Another option for treating bacterial ear infections and inflammation.
  • Ofloxacin Otic: An antibiotic used to treat bacterial ear infections, particularly if corticosteroids are not needed.