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Cleocin-T
Cleocin-T is a topical antibiotic containing clindamycin phosphate, primarily used to treat acne vulgaris. It belongs to the lincosamide class of antibiotics and works by inhibiting bacterial growth, particularly Propionibacterium acnes, the bacteria responsible for acne. Cleocin-T is available as a topical gel, lotion, solution, and foam, offering options for treating mild to moderate acne on the face and body.
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Frequently Asked Questions
How long does it take for Cleocin-T to work?
Cleocin-T may take several weeks to show noticeable improvement in acne. For best results, continue using the medication as prescribed by your healthcare provider.
Can I use makeup while using Cleocin-T?
Yes, you can use makeup while using Cleocin-T. However, choose oil-free or non-comedogenic products to avoid clogging your pores.
Can I use Cleocin-T with other acne medications?
It is best to consult your healthcare provider before combining Cleocin-T with other acne treatments, as using multiple products may increase the risk of skin irritation.
What should I do if I miss a dose of Cleocin-T?
If you miss a dose, apply it as soon as you remember. If it is close to your next scheduled dose, skip the missed dose and resume your regular schedule. Do not double up on doses.
Is Cleocin-T safe during pregnancy?
Clindamycin is considered safe for use during pregnancy, but it is important to consult your healthcare provider before using any medication while pregnant or breastfeeding.
Comprehensive Drug Guide
How Does Cleocin-T Work?
Cleocin-T contains clindamycin, which works by inhibiting bacterial protein synthesis by binding to the 50S ribosomal subunit. This action prevents bacteria from growing and multiplying, helping to reduce acne-causing bacteria on the skin. As a result, it reduces inflammation and the severity of acne lesions.
Common Dosages
- Gel: 1% clindamycin phosphate
- Lotion: 1% clindamycin phosphate
- Solution: 1% clindamycin phosphate
- Foam: 1% clindamycin phosphate
Typical Dosing
- For acne: Apply a thin layer to the affected area once or twice daily as directed by your healthcare provider. Wash the skin with a mild cleanser and allow it to dry before applying Cleocin-T.
Typical Dosing
FDA Approved Indications
Acne vulgaris (mild to moderate acne)
Who Shouldn't Take Cleocin-T?
- Hypersensitivity to clindamycin or lincomycin
- History of regional enteritis, ulcerative colitis, or antibiotic-associated colitis
Advice From The Pharmacist
- Apply Cleocin-T to clean, dry skin, and use it exactly as prescribed. Do not use more than recommended, as this may increase the risk of side effects.
- Avoid contact with the eyes, mouth, and other mucous membranes. If contact occurs, rinse thoroughly with water.
- Cleocin-T is for external use only. Do not apply it to broken or irritated skin.
- You may experience mild skin dryness or irritation during the first few weeks of use. If irritation becomes severe, contact your healthcare provider.
- It may take several weeks to see noticeable improvement in your acne. Continue using the medication as prescribed, even if your symptoms improve.
Side Effects of Cleocin-T
Common Side Effects
- Dry or peeling skin
- Mild skin irritation (redness, itching)
- Oiliness or shininess
- Burning or stinging sensation
Uncommon/Severe Side Effects
- Severe allergic reactions (rash, swelling, difficulty breathing)
- Diarrhea or colitis (in rare cases, clindamycin can be absorbed systemically and lead to gastrointestinal side effects)
- Severe skin irritation or contact dermatitis
Risks and Warnings of Cleocin-T
- Diarrhea and Colitis: Though rare, clindamycin may cause severe diarrhea or colitis, even when applied topically. If you experience persistent diarrhea or signs of colitis, such as abdominal pain or blood in the stool, stop using Cleocin-T and contact your healthcare provider.
- Photosensitivity: Avoid prolonged sun exposure, tanning booths, or sunlamps while using Cleocin-T, as it may make your skin more sensitive to sunlight. Use sunscreen and protective clothing when outdoors.
- Skin Irritation: If severe skin irritation develops, discontinue use and consult your healthcare provider. Cleocin-T may not be suitable for individuals with very sensitive skin.
Interactions with Cleocin-T
Common Drug Interactions
- Topical Acne Treatments: Cleocin-T may cause increased skin irritation when used with other acne treatments, especially those containing benzoyl peroxide, retinoids, or salicylic acid.
- Oral Clindamycin: Using topical clindamycin with oral clindamycin may increase the risk of systemic side effects, including diarrhea and colitis.
Alternatives to Cleocin-T
- Benzoyl Peroxide (Benzaclin): A topical antibiotic/antimicrobial used for acne that may be combined with clindamycin for dual therapy.
- Topical Retinoids (Tretinoin): Used to treat acne by promoting cell turnover and preventing clogged pores.
- Doxycycline: An oral antibiotic used for moderate to severe acne when topical treatments are insufficient.
- Azelaic Acid (Azelex): A topical treatment that helps to clear pores and reduce bacterial growth.
