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Ciprofloxacin-Fluocinolone PF
Ciprofloxacin-Fluocinolone PF is a combination medication used to treat acute otitis externa (swimmer's ear) and other bacterial ear infections accompanied by inflammation. Ciprofloxacin is a fluoroquinolone antibiotic that works by inhibiting bacterial growth, while fluocinolone is a corticosteroid that reduces inflammation, redness, and swelling in the ear. This preservative-free (PF) formulation is designed for patients sensitive to preservatives. Ciprofloxacin-Fluocinolone PF is typically prescribed in otic suspension (ear drops) form to alleviate infection and inflammation in the ear.
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Frequently Asked Questions
How long does it take for Ciprofloxacin-Fluocinolone PF to work?
Most patients start to see improvement within 2 to 3 days, but it is important to complete the full course (typically 7 days) to ensure the infection is fully treated.
Can Ciprofloxacin-Fluocinolone PF be used for viral or fungal ear infections?
No, this medication is effective only against bacterial infections. It will not work for viral or fungal infections. Your doctor will recommend the appropriate treatment if you have a different type of infection.
What should I do if I miss a dose?
If you miss a dose, apply it as soon as you remember. If it is close to your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose.
Can I swim while using Ciprofloxacin-Fluocinolone PF?
It is recommended to avoid swimming or exposing your ear to water while using this medication to prevent further irritation or prolonging the infection.
Is Ciprofloxacin-Fluocinolone PF safe for children?
Yes, this medication is safe for children aged 6 months and older. Always follow your pediatrician’s dosing instructions carefully to ensure safe and effective treatment.
Comprehensive Drug Guide
How Does Ciprofloxacin-Fluocinolone PF Work?
Ciprofloxacin, the antibiotic component, works by inhibiting bacterial DNA gyrase and topoisomerase IV, which are essential for bacterial DNA replication, transcription, and repair. This action stops bacterial growth and kills the infection-causing bacteria. Fluocinolone, a corticosteroid, reduces inflammation by suppressing the immune response that leads to swelling, pain, and redness in the ear.
Common Dosages
- Otic Suspension (preservative-free): Each mL contains 0.3% ciprofloxacin and 0.025% fluocinolone acetonide.
Typical Dosing
- For acute otitis externa: Instill 4 drops into the affected ear twice daily for 7 days. Follow your healthcare provider's instructions to ensure complete treatment.
Typical Dosing
FDA Approved Indications
Acute otitis externa (swimmer’s ear) caused by susceptible bacteria
Who Shouldn't Take Ciprofloxacin-Fluocinolone PF?
- Hypersensitivity to ciprofloxacin, fluocinolone, or other quinolone antibiotics
- Viral or fungal ear infections
- Perforated eardrum (unless otherwise directed by a healthcare provider)
Advice From The Pharmacist
- Warm the bottle by holding it in your hands before administering the drops to avoid dizziness caused by cold ear drops.
- Lie down or tilt your head with the affected ear facing upward. Stay in this position for a few minutes after administering the drops to ensure absorption.
- Avoid swimming or getting water in the affected ear while using Ciprofloxacin-Fluocinolone PF, as this can interfere with healing.
- Complete the entire course of treatment, even if symptoms improve early, to prevent recurrence of the infection.
- If using other ear medications, consult your healthcare provider to determine the best dosing schedule to avoid interactions.
Side Effects of Ciprofloxacin-Fluocinolone PF
Common Side Effects
- Mild itching or discomfort in the ear
- Temporary stinging or burning sensation after application
- Feeling of fullness in the ear
Uncommon/Severe Side Effects
- Severe allergic reactions (rash, swelling, difficulty breathing)
- Worsening ear pain or hearing changes
- Dizziness or lightheadedness
Risks and Warnings of Ciprofloxacin-Fluocinolone PF
- Allergic Reactions: Ciprofloxacin-Fluocinolone PF should not be used if you are allergic to quinolones or corticosteroids. Discontinue use and seek immediate medical attention if signs of an allergic reaction occur.
- Superinfection: Prolonged use of this medication may lead to secondary infections, such as fungal or viral ear infections. Consult your doctor if symptoms worsen or persist.
- Perforated Eardrum: This medication should not be used if you suspect a perforated eardrum, unless directed by your doctor. Using it in the presence of a perforated eardrum may cause complications.
Interactions with Ciprofloxacin-Fluocinolone PF
Common Drug Interactions
Systemic drug interactions are unlikely due to the topical application of Ciprofloxacin-Fluocinolone PF. However, you should inform your healthcare provider of all medications, supplements, or herbal products you are taking to avoid any potential conflicts.
Alternatives to Ciprofloxacin-Fluocinolone PF
- Ofloxacin (Floxin Otic): A fluoroquinolone antibiotic used for bacterial ear infections.
- Ciprofloxacin Otic Solution: An antibiotic-only formulation for treating bacterial ear infections.
- Polymyxin B-neomycin-hydrocortisone (Cortisporin Otic): Another combination antibiotic and corticosteroid formulation for ear infections and inflammation.
