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Benztropine Mesylate

Benztropine is a medication known as an anticholinergic, commonly used to treat Extrapyramidal symptoms (medication-induced movement disorder) and parkinsonism.

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Frequently Asked Questions

Can I take benztropine if I have glaucoma?
Open FAQClose FAQ

No, if you have narrow-angle glaucoma, a type of eye disease, you shouldn't take benztropine.

Does benztropine cause dry mouth?
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Yes, dry mouth is a common side effect of benztropine. Chewing sugarless gum or sipping water might help.

I missed a dose of benztropine, what should I do?
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If it's close to the time of your next dose, then skip the missed one. If it's been a while, you can take the missed dose as soon as you remember. But do not double the doses.

Can I just stop taking benztropine when my symptoms are managed?
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Not recommended without consulting a doctor. There should be a gradual decrease in the drug as abrupt discontinuation could lead to a rapid return of symptoms.

I felt a bit dizzy after taking benztropine. What should I do?
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Consult your healthcare provider. It might be a side effect. Try to move slowly, especially when getting up from a sitting or lying position.

Can I have my usual wine/beer while on benztropine?
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It's better not to as alcohol can make side effects like drowsiness and dizziness worse. If you have to drink, do it in moderation. Always a good idea to check with your healthcare professional.

Comprehensive Drug Guide

How Does Benztropine Mesylate Work?

Benztropine is an oral anticholinergic agent that functions by inhibiting the neurotransmitter acetylcholine in the nervous system; this helps restore the balance of acetylcholine and dopamine in the brain.

What is Benztropine Mesylate Used For?

It's indicated for use as an adjunct in the therapy of Parkinson's disease and control of extrapyramidal disorders caused by drugs.

Common Dosages

Tablets:

  • 0.5mg

  • 1mg
  • 2mg

Typical Dosing

FDA Approved Indications

  • For Parkinson's disease: 0.5 to 1 mg at bedtime
  • For extrapyramidal disorders: 1 to 2 mg one or two times per day.

Who Shouldn't Take Benztropine Mesylate?

  • If you are allergic to benztropine or any other components of the medication.
  • If you have been diagnosed with narrow-angle glaucoma.
  • Suffering from urinary retention.
  • Individuals with myasthenia gravis.
  • If you are pregnant, plan on becoming pregnant or breastfeeding, consult your doctor before use.

Advice From The Pharmacist

  • This medication can cause dry mouth; frequent mouth care, sucking sugarless candy, or chewing sugarless gum may provide relief.
  • This medication can cause blurred vision, avoid driving or operating machinery until you are sure you can do these activities safely.
  • If a dose is missed, take it as soon as you remember if it's not close to the time for the next dose. Never double the dose.

Side Effects of Benztropine Mesylate

Common Side Effects

  • You might have dry mouth, blurred vision, or dizziness.
  • You might also feel constipated.

Uncommon/Severe Side Effects

  • You might feel difficulty in passing urine.
  • If you have high fever or mental/mood changes like hallucinations, confusion, anxiety, immediately seek medical help.
  • Any signs of an allergic reaction like rash, itching, severe dizziness should be reported immediately.

Risks and Warnings of Benztropine Mesylate

Pregnancy and Breastfeeding: The FDA has labeled Benztropine as a category C pregnancy drug. This means it should only be utilized during pregnancy if the benefits substantially outweigh the risks. Its effects during breastfeeding are not well known, so it's advisable to consult with your healthcare provider beforehand.

Substance Abuse and Dependence: While Benztropine has a relatively low risk of dependence, some individuals may misuse the drug to feel euphoria or relaxation, often in combination with other substances.

Elderly Use: Elderly patients may be more sensitive to the anticholinergic effects of Benztropine. Thus, they should be closely monitored while on this medication. They may have a higher risk for conditions such as delirium, acute confusional state, constipation, or urinary retention.

Interactions with Benztropine Mesylate

Common Drug Interactions

  • Antihistamines
  • Antipsychotics
  • Certain antiarrhythmics
  • Certain antihypertensives
  • Tricyclic antidepressants
  • Alcohol

Alternatives to Benztropine Mesylate

  • Trihexyphenidyl
  • Carbidopa-Levodopa
  • Pramipexole
  • Ropinirole
  • Entacapone