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Ashlyna

Ashlyna is a combination oral contraceptive pill that contains levonorgestrel (a progestin) and ethinyl estradiol (an estrogen). It is used to prevent pregnancy by inhibiting ovulation, thickening cervical mucus, and altering the uterine lining to make it more difficult for sperm to reach an egg and for a fertilized egg to implant. Ashlyna is a 91-day extended-cycle pill, meaning it allows for an extended period of active hormonal pills, followed by a shorter inactive pill phase, leading to fewer menstrual periods (only four per year).



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Frequently Asked Questions

How does Ashlyna reduce the number of periods?
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Ashlyna follows a 91-day cycle, with 84 days of active hormone pills and 7 days of inactive pills. This extended regimen reduces the number of withdrawal bleeds to just four per year, rather than the typical monthly cycle with most oral contraceptives.

What should I do if I miss a pill?
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If you miss one active pill, take it as soon as you remember and take the next pill at your regular time. If you miss two or more pills, follow the instructions in the patient leaflet, and use a backup method of contraception (such as condoms) for the next 7 days.

Can Ashlyna cause weight gain?
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Some women may experience weight gain while taking Ashlyna, but it is usually minimal and may be related to water retention rather than fat gain.

Can I use Ashlyna to skip my period entirely?
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Ashlyna is designed to reduce the number of periods, but it does not completely eliminate them. If you wish to skip your period, consult your healthcare provider for options, as continuous-use contraceptives may be more suitable for that purpose.

Does Ashlyna protect against sexually transmitted infections (STIs)?
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No, Ashlyna does not protect against STIs. You should use condoms or other barrier methods to reduce the risk of contracting or spreading infections.

Comprehensive Drug Guide

How Does Ashlyna Work?

Ashlyna works by inhibiting ovulation (the release of an egg from the ovaries), thickening the cervical mucus to prevent sperm from reaching the egg, and changing the lining of the uterus to make it less suitable for a fertilized egg to implant. These actions collectively help prevent pregnancy.



Common Dosages

  • 84 active tablets: Each tablet contains 0.15 mg of levonorgestrel and 0.03 mg of ethinyl estradiol.
  • 7 inactive tablets: These are taken during the last 7 days of the cycle to allow for a withdrawal bleed (similar to a menstrual period).

Typical Dosing

  • Take one active tablet daily for 84 consecutive days, followed by one inactive tablet daily for 7 days.
  • During the week of inactive pills, you may experience a withdrawal bleed (similar to a period).
  • Start the next 91-day cycle immediately after finishing the inactive pills, regardless of whether bleeding has stopped.


Typical Dosing

FDA Approved Indications

  • Contraception (pregnancy prevention) in women of reproductive age


Who Shouldn't Take Ashlyna?

  • A history of blood clots, stroke, or heart attack
  • Known or suspected breast cancer or estrogen-dependent tumors
  • Liver disease
  • Uncontrolled high blood pressure
  • Migraines with aura


Advice From The Pharmacist

  • Take Ashlyna at the same time every day to maintain consistent hormone levels and maximize its effectiveness in preventing pregnancy.
  • If you miss a pill, follow the instructions provided in the patient information leaflet, as missing pills can increase the risk of pregnancy.
  • Ashlyna does not protect against sexually transmitted infections (STIs). Use a barrier method, such as condoms, to protect against STIs.
  • Smoking while taking Ashlyna increases the risk of serious cardiovascular side effects, particularly in women over 35 years of age.


Side Effects of Ashlyna

Common Side Effects

  • Nausea
  • Breast tenderness
  • Headache
  • Weight gain
  • Breakthrough bleeding (especially during the first few months)


Uncommon/Severe Side Effects

  • Blood clots
  • Stroke
  • Heart attack
  • Liver problems


Risks and Warnings of Ashlyna

  • Cardiovascular risk: Women over the age of 35 who smoke should not use Ashlyna, as it increases the risk of serious cardiovascular events like blood clots, heart attack, or stroke.
  • Blood clots: Ashlyna may increase the risk of venous thromboembolism (blood clots), particularly in women with predisposing risk factors such as smoking or a history of clotting disorders.
  • Breast cancer risk: Hormonal contraceptives, including Ashlyna, may slightly increase the risk of breast cancer, especially in women with a family history of the disease.


Interactions with Ashlyna

Common Drug Interactions

  • Certain antibiotics (such as rifampin) and antifungal medications may reduce the effectiveness of Ashlyna, increasing the risk of pregnancy.
  • Antiepileptic drugs (such as carbamazepine and phenytoin) may decrease the effectiveness of Ashlyna.
  • St. John’s Wort: This herbal supplement may reduce the effectiveness of Ashlyna by accelerating the breakdown of hormones in the liver.


Alternatives to Ashlyna

  • LoSeasonique: Another extended-cycle contraceptive pill that provides fewer menstrual periods per year.
  • Seasonique: Similar to Ashlyna, this is a 91-day extended-cycle birth control pill with a slightly different hormonal combination.
  • NuvaRing: A monthly vaginal ring contraceptive that delivers a continuous dose of estrogen and progestin.
  • Intrauterine devices (IUDs): Long-term, reversible birth control options, such as Mirena (hormonal) or ParaGard (copper).