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Arnuity Ellipta
Arnuity Ellipta is an inhaled corticosteroid (ICS) used for the maintenance treatment of asthma in patients aged 5 years and older. The active ingredient in Arnuity Ellipta is fluticasone furoate, which helps to reduce inflammation in the airways, making it easier to breathe. Arnuity Ellipta is not intended for the relief of acute bronchospasm or sudden asthma attacks, but rather for regular, long-term control of asthma symptoms.
Drug Availability and Controlled Substance Status
Arnuity Ellipta is available by prescription only and comes as a dry powder inhaler (DPI) that delivers a pre-measured dose of fluticasone furoate with each inhalation. It is not classified as a controlled substance. The inhaler is typically provided in doses of 50 mcg, 100 mcg, or 200 mcg per inhalation.
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Frequently Asked Questions
How long does it take for Arnuity Ellipta to start working?
Arnuity Ellipta may start to improve asthma symptoms within 24 hours, but it may take up to 2 weeks of regular use to achieve the full benefit. Patients should continue using the inhaler as prescribed, even if they feel better.
Can Arnuity Ellipta be used with a rescue inhaler?
Yes, Arnuity Ellipta is used for long-term asthma control and should be used daily. A rescue inhaler, such as albuterol, should be used for immediate relief of acute asthma symptoms.
What should I do if I miss a dose of Arnuity Ellipta?
If you miss a dose, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and take your next dose at the regular time. Do not take two doses at once.
Is Arnuity Ellipta safe to use during pregnancy?
The safety of Arnuity Ellipta during pregnancy has not been fully established. Pregnant women or those planning to become pregnant should consult their healthcare provider to discuss the potential risks and benefits of using this medication during pregnancy.
Can I use Arnuity Ellipta if I have other health conditions?
Patients with other health conditions, such as glaucoma, osteoporosis, or a history of infections, should inform their healthcare provider before using Arnuity Ellipta. The provider may recommend additional monitoring or adjustments to the treatment plan based on the patient's overall health.
Comprehensive Drug Guide
How Does Arnuity Ellipta Work?
Fluticasone furoate, the active ingredient in Arnuity Ellipta, works by reducing inflammation in the airways. It does this by inhibiting the release of inflammatory substances, such as cytokines and leukotrienes, that contribute to the swelling and narrowing of the airways. By reducing inflammation, Arnuity Ellipta helps to prevent asthma symptoms such as wheezing, coughing, and shortness of breath, and improves overall lung function.
What is Arnuity Ellipta Used For?
Common Dosages
The typical dosage of Arnuity Ellipta for adults and children aged 12 years and older is 100 mcg or 200 mcg inhaled once daily. For children aged 5 to 11 years, the usual dose is 50 mcg inhaled once daily. The dose may be adjusted by the healthcare provider based on the patient's response to treatment and the severity of asthma.
Typical Dosing
Arnuity Ellipta is typically taken once daily, at the same time each day, to ensure consistent control of asthma symptoms. The inhaler should be used exactly as prescribed, and the dose should not be skipped or doubled. Patients should be instructed on the proper technique for using the inhaler to ensure the medication is delivered effectively to the lungs.
Typical Dosing
FDA Approved Indications
Arnuity Ellipta is FDA-approved for the maintenance treatment of asthma in patients aged 5 years and older. It is intended for daily use to control asthma symptoms and prevent asthma attacks. Arnuity Ellipta is not approved for the treatment of acute bronchospasm or as a rescue inhaler.
Who Shouldn't Take Arnuity Ellipta?
Arnuity Ellipta is contraindicated in patients with a known hypersensitivity to fluticasone furoate or any of the other ingredients in the inhaler. It should not be used for the relief of acute bronchospasm, and patients should have a rescue inhaler (such as albuterol) available for this purpose. Caution is advised in patients with a history of severe allergic reactions to corticosteroids or those with untreated systemic infections, as corticosteroids can suppress the immune response.
Advice From The Pharmacist
Patients using Arnuity Ellipta should be advised to use the inhaler daily, even if they feel well and are not experiencing asthma symptoms. It is important to rinse the mouth with water and spit it out after each use to reduce the risk of oral thrush, a potential side effect of inhaled corticosteroids. Patients should be reminded that Arnuity Ellipta is not a rescue inhaler and should not be used to treat sudden asthma attacks. If asthma symptoms worsen or if the rescue inhaler becomes less effective, patients should contact their healthcare provider promptly.
Side Effects of Arnuity Ellipta
Common Side Effects
Common side effects of Arnuity Ellipta include headache, sore throat, cough, and hoarseness. Some patients may also experience oral thrush, which can be prevented by rinsing the mouth after each use. Serious side effects, though rare, can include decreased bone density, slowed growth in children, and an increased risk of infections due to immune suppression. Patients should seek medical attention if they experience signs of an allergic reaction, such as rash, itching, swelling, or difficulty breathing.
Interactions with Arnuity Ellipta
Common Drug Interactions
Arnuity Ellipta may interact with other medications, including strong CYP3A4 inhibitors such as ketoconazole or ritonavir, which can increase the levels of fluticasone furoate in the blood and raise the risk of side effects. Patients should inform their healthcare provider of all medications and supplements they are taking to avoid potential interactions. Use of other inhaled corticosteroids or oral corticosteroids concurrently with Arnuity Ellipta may increase the risk of systemic side effects.
Alternatives to Arnuity Ellipta
Alternative treatments for asthma include other inhaled corticosteroids, such as budesonide (Pulmicort) or fluticasone propionate (Flovent), as well as combination inhalers that contain both an inhaled corticosteroid and a long-acting beta-agonist (LABA), such as fluticasone/salmeterol (Advair) or budesonide/formoterol (Symbicort). The choice of treatment depends on the severity of asthma, the patient's response to previous therapies, and overall health considerations.
