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Amnesteem
Amnesteem, also known as isotretinoin, is a potent medication used in the treatment of severe acne that has not responded to other treatments. Some common side effects include dry skin, chapped lips, and sun sensitivity, but your doctor will thoroughly weigh the benefits against these issues.
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Frequently Asked Questions
Can I take Amnesteem with milk?
Yes, you can. It is recommended that this medication is taken with food or milk for best absorption.
Can I wax my eyebrows or other parts of my body while using Amnesteem?
Waxing is not recommended while you are on Amnesteem or for several months after stopping it, due to the severe skin reactions it may cause.
Is it safe to use Amnesteem and drink alcohol?
Drinking alcohol affects liver function and could potentially increase the risk of elevated liver enzymes. Therefore, limits on alcohol consumption may be proposed when using Amnesteem. Please consult with your healthcare provider for guidance.
What should I do if I forget a dose?
Take the missed dose as soon as you remember, but if it is nearly time for your next one, then you should just skip the missed dose. Do not take multiple doses to catch up.
Will Amnesteem cure my acne forever?
It helps to clear severe acne, but in some cases, the acne might return. You should consult with your doctor to determine the best acne management plan for your specific condition.
Will I be able to get pregnant after using Amnesteem?
Yes. However, you should not get pregnant while taking Amnesteem due to the severe risk of birth defects. It's recommended to wait at least one month after stopping the medication before trying to become pregnant.
Comprehensive Drug Guide
How Does Amnesteem Work?
Amnesteem is a synthetic derivative of vitamin A that impacts cellular differentiation, proliferation, and apoptosis to effectively treat severe acne by reducing sebum production, altering follicular keratinization, and decreasing inflammation.
What is Amnesteem Used For?
FDA indications: Amnesteem is primarily used to treat nodular acne that has not responded to other treatments.
Offlabel uses: It has been used for treating lesser forms of acne only when other treatments have failed.
Common Dosages
Oral capsules: 10mg, 20mg, 30mg, and 40mg
Typical Dosing
FDA Approved Indications
- The dosage depends on the patient's weight, medical condition, and response to treatment. Generally, Amnesteem is taken twice daily for 1520 weeks or as directed by your doctor.
Who Shouldn't Take Amnesteem?
- Known hypersensitivity or allergic reaction to any of the components in the formulation
- Pregnant women, those planning to become pregnant, or are breastfeeding
- Liver disease
- Severely high lipid levels
- Concurrent use of tetracyclines (major drug interaction)
Advice From The Pharmacist
- You should have two negative pregnancy tests before starting Amnesteem and use two forms of birth control, due to its heavily teratogenic effects.
- Do not donate blood while taking Amnesteem and for one month after stopping treatment.
- Beware that Amnesteem can make your skin more fragile, drier, and sensitive to the sun. Use sunscreen and be cautious with waxing, exfoliating, or laser treatments.
- You should have monthly lab tests to monitor your liver and lipid levels while taking this medication.
- It's important to stay wellhydrated and use moisturizers for your skin and lip balms for your lips to manage dryness.
- Finally, your mental health matters. Isotretinoin can sometimes cause depression, anxiety, and mood changes. Don?t hesitate to reach out to your healthcare provider if you are experiencing emotional or mental struggles while taking this medicine.
Side Effects of Amnesteem
Common Side Effects
- Dry skin, dry eyes, dry nose, dry lips
- Itches, rashes, sensitivity to the sun
- Nosebleeds
- Changes in your fingernails or toenails, such as swelling in your nails or slower growth
- Back pain, muscle, and joint stiffness, bone pain, or fracture
Uncommon/Severe Side Effects
- Depression, anxiety, aggressive or violent behaviors, mood swings
- Symptoms of increased intracranial pressure like nausea, vomiting, and severe headaches
- Stomach issues, such as stomach pain, bloody stools, or ongoing diarrhea
- Severe skin reactions, such as a rash or red patches
- Difficulty breathing or swallowing
Risks and Warnings of Amnesteem
- Failure to take Amnesteem as prescribed or misuse can result in serious side effects, including severe physical birth defects, mental retardation, or lifethreatening allergic reactions. Taking more than the recommended dose will not result in improved or faster therapeutic results, but may cause serious health problems.
Interactions with Amnesteem
Common Drug Interactions
- Vitamin A
- Tetracyclines (such as doxycycline and minocycline)
- Certain seizure medications (phenytoin)
- St. John's Wort
Alternatives to Amnesteem
- Tretinoin
- Adapalene
- Azelaic acid
- Topical Rx treatments
- Overthecounter treatments
