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Alvesco
Alvesco (ciclesonide) is an inhaled corticosteroid used for the maintenance treatment of asthma in patients aged 12 years and older. It helps reduce inflammation in the airways, leading to improved breathing and a decrease in asthma attacks. Alvesco works by targeting the underlying inflammation that contributes to asthma symptoms, providing long-term control and management of the condition.
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Frequently Asked Questions
How long does it take for Alvesco to start working?
Alvesco may take several hours to a few days to notice improvements in asthma control, but it is essential to use it regularly for optimal effectiveness.
Can I use Alvesco during an asthma attack?
No, Alvesco is not intended for the relief of acute asthma attacks. A fast-acting bronchodilator (such as albuterol) should be used for quick relief.
What should I do if I miss a dose of Alvesco?
If you miss a dose, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
Is it safe to use Alvesco during pregnancy?
Consult your healthcare provider if you are pregnant or planning to become pregnant, as the risks and benefits should be assessed individually.
Can I stop using Alvesco suddenly?
Do not stop using Alvesco suddenly without consulting your healthcare provider, especially if you have been on systemic corticosteroids, as a tapering approach may be necessary.
Comprehensive Drug Guide
How Does Alvesco Work?
Alvesco works by binding to glucocorticoid receptors in the airways, leading to the regulation of gene expression that controls inflammation. This action reduces the release of inflammatory mediators, leading to decreased swelling and irritation in the airways. As a result, Alvesco helps improve airflow and reduces the frequency of asthma symptoms and exacerbations.
Common Dosages
- Inhalation aerosol: 80 mcg and 160 mcg per actuation
Typical Dosing
- The typical starting dose of Alvesco is 80 mcg to 160 mcg inhaled once daily. The dose may be adjusted based on the severity of asthma and patient response, with a maximum recommended dose of 320 mcg per day.
Typical Dosing
FDA Approved Indications
- Maintenance treatment of asthma in patients aged 12 years and older as part of a comprehensive asthma management plan
Who Shouldn't Take Alvesco?
- Known hypersensitivity to ciclesonide or any components of the formulation
- Acute asthma attacks or status asthmaticus
Advice From The Pharmacist
- Use Alvesco exactly as prescribed, and ensure proper inhaler technique to maximize drug delivery to the lungs.
- Rinse your mouth with water after each use to minimize the risk of oral thrush and other side effects.
- Regularly monitor asthma symptoms and response to treatment, and inform your healthcare provider of any changes.
- Avoid sudden discontinuation of Alvesco if you are transitioning from systemic corticosteroids, as this may require a tapering approach.
Side Effects of Alvesco
Common Side Effects
- Headache
- Sore throat
- Cough
- Nasal congestion
Uncommon/Severe Side Effects
- Oral candidiasis (thrush)
- Adrenal suppression (with long-term use)
- Pneumonia (in patients with COPD)
Risks and Warnings of Alvesco
- Infections: Patients using Alvesco should be monitored for signs of infection, as corticosteroids can suppress the immune response.
- Adrenal Insufficiency: Long-term use of corticosteroids may lead to adrenal insufficiency; patients should be aware of symptoms such as fatigue, weakness, or low blood pressure.
- Growth Suppression: In pediatric patients, long-term use of inhaled corticosteroids may impact growth; regular monitoring is recommended.
Interactions with Alvesco
Common Drug Interactions
- CYP3A4 Inhibitors: Use with medications that inhibit the CYP3A4 enzyme may increase the effects of ciclesonide and increase the risk of side effects.
- Other Corticosteroids: Concurrent use with other corticosteroids may enhance the risk of systemic side effects.
Alternatives to Alvesco
- Other inhaled corticosteroids: Such as fluticasone, budesonide, or beclomethasone, which can also help manage asthma.
- Leukotriene receptor antagonists: Medications like montelukast may be used as an alternative or in conjunction with inhaled corticosteroids.
- Long-acting beta-agonists (LABAs): Such as salmeterol, may be used in combination with inhaled corticosteroids for better control of asthma.
