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AirDuo Digihaler

AirDuo Digihaler is a combination inhaler used to manage asthma in patients aged 12 years and older. It contains two active ingredients: fluticasone propionate, a corticosteroid that reduces inflammation in the airways, and salmeterol, a long-acting beta-agonist (LABA) that helps to relax and open the airways. The "Digihaler" aspect refers to its digital component, which connects to a smartphone app to track inhaler usage, helping patients and healthcare providers monitor treatment adherence. AirDuo Digihaler is not intended for the relief of acute bronchospasm but is used for long-term control and prevention of asthma symptoms.


AirDuo Digihaler is available by prescription only and can be found in most pharmacies. It is provided as an inhalation aerosol in different strengths. AirDuo Digihaler is not classified as a controlled substance, but it requires a prescription due to the need for proper usage and monitoring, especially with its digital tracking feature.


AirDuo Digihaler belongs to two formal drug classes: corticosteroids (fluticasone propionate) and long-acting beta-agonists (salmeterol). Informally, it may be referred to as a combination asthma inhaler. These classifications relate to its role in reducing inflammation and relaxing airway muscles to prevent asthma symptoms.



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Frequently Asked Questions

Can I use AirDuo Digihaler for sudden asthma symptoms?
Open FAQClose FAQ

No, AirDuo Digihaler is not intended for relief of acute bronchospasm. You should use a rescue inhaler, such as albuterol, for sudden asthma symptoms.

How do I sync AirDuo Digihaler with the app?
Open FAQClose FAQ

Follow the instructions provided with the Digihaler app to sync the inhaler. The app will track your inhaler usage and provide data that you can share with your healthcare provider.

What should I do if I miss a dose of AirDuo Digihaler?
Open FAQClose FAQ

If you miss a dose, take it as soon as you remember. If it is close to your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not double up on doses.

Can AirDuo Digihaler be used in children?
Open FAQClose FAQ

AirDuo Digihaler is approved for use in patients aged 12 years and older. The safety and effectiveness in children younger than 12 have not been established.

Are there any dietary restrictions while using AirDuo Digihaler?
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There are no specific dietary restrictions, but maintaining a balanced diet and regular exercise is beneficial for overall health and asthma management.

Comprehensive Drug Guide

How Does AirDuo Digihaler Work?

AirDuo Digihaler works through the combined action of its two active ingredients. Fluticasone propionate is a corticosteroid that decreases inflammation in the airways, reducing swelling and irritation. Salmeterol, the long-acting beta-agonist, relaxes the smooth muscles around the airways, helping to keep them open and making it easier to breathe. Together, these actions help to prevent asthma attacks and improve lung function over time. The digital component tracks inhaler usage, providing valuable data to enhance treatment adherence and effectiveness.



Common Dosages

AirDuo Digihaler is available in multiple strengths, including:

  • 55 mcg fluticasone propionate / 14 mcg salmeterol
  • 113 mcg fluticasone propionate / 14 mcg salmeterol
  • 232 mcg fluticasone propionate / 14 mcg salmeterol

The appropriate dosage is determined based on the patient's asthma severity and response to treatment. The typical dosing involves two inhalations twice daily.


The typical dosing for AirDuo Digihaler involves two inhalations taken twice daily, approximately 12 hours apart. It is important to use the inhaler regularly, even when symptoms are not present, to maintain control of asthma. Patients should be instructed on the proper inhalation technique and how to sync the inhaler with the Digihaler app for optimal tracking.



Typical Dosing

FDA Approved Indications

AirDuo Digihaler is FDA-approved for the maintenance treatment of asthma in patients aged 12 years and older. It is not indicated for the relief of acute bronchospasm or as a rescue inhaler. The inhaler is intended for long-term use as part of an asthma management plan, helping to prevent symptoms and improve overall lung function.



Who Shouldn't Take AirDuo Digihaler?

AirDuo Digihaler should not be used in individuals who:

  • Are allergic to fluticasone propionate, salmeterol, or any other components of the inhaler
  • Are experiencing acute bronchospasm or asthma attacks requiring immediate bronchodilation
  • Have severe hypersensitivity to milk proteins, as the inhaler may contain lactose

It should also be used with caution in patients with cardiovascular disorders, diabetes, or infections.



Advice From The Pharmacist

When using AirDuo Digihaler, it is important to follow the prescribed dosing schedule closely. Make sure to inhale the medication correctly and to use the inhaler consistently to prevent asthma symptoms. Sync the inhaler with the accompanying smartphone app to monitor your usage and share the data with your healthcare provider. Do not use AirDuo Digihaler as a rescue inhaler for sudden asthma symptoms; instead, use a short-acting bronchodilator. If you miss a dose, take it as soon as you remember, but do not double up on doses. Regular check-ups are essential to assess the effectiveness of the treatment and to make any necessary adjustments.



Side Effects of AirDuo Digihaler

Common Side Effects

Common side effects of AirDuo Digihaler may include:

  • Headache
  • Throat irritation
  • Hoarseness
  • Cough
  • Upper respiratory infections


Uncommon/Severe Side Effects

Serious side effects, though rare, may include:

  • Increased risk of asthma-related death (due to the LABA component)
  • Fungal infections (e.g., oral thrush)
  • Immunosuppression
  • Osteoporosis
  • Cardiovascular effects (e.g., palpitations, tachycardia)

If any serious side effects occur, seek medical attention immediately.



Risks and Warnings of AirDuo Digihaler

The major risks associated with AirDuo Digihaler include the potential for asthma-related death, particularly with the LABA component when used without a corticosteroid. However, the combination in AirDuo Digihaler mitigates this risk. Patients should be regularly monitored for side effects, particularly for infections and bone density changes. It is crucial not to discontinue the inhaler abruptly without consulting a healthcare provider, as this can lead to a worsening of asthma symptoms.



Interactions with AirDuo Digihaler

Common Drug Interactions

AirDuo Digihaler can interact with several medications, including:

  • Beta-blockers, which may reduce the effectiveness of salmeterol
  • Antifungal medications (e.g., ketoconazole), which can increase the levels of fluticasone and salmeterol
  • Diuretics, which can increase the risk of hypokalemia
  • MAO inhibitors and tricyclic antidepressants, which can enhance the cardiovascular effects of salmeterol

It is important to inform your healthcare provider of all medications, supplements, and over-the-counter products you are taking to avoid potential interactions.



Alternatives to AirDuo Digihaler

Alternative asthma treatments include other combination inhalers such as Advair (fluticasone/salmeterol), Symbicort (budesonide/formoterol), and Breo Ellipta (fluticasone/vilanterol). Additionally, single-agent inhalers like Pulmicort (budesonide) or rescue inhalers like albuterol may be used in conjunction with or as alternatives to AirDuo Digihaler. Discuss these options with your healthcare provider to find the best fit for your asthma management plan.