NiHowdy > Drug Classes > Antithyroid Agents

Browse Medications by Drug Class: Antithyroid Agents

Written by Amar Lunagaria

Pharm.D • NiHowdy Founder

Reviewed by James Wong

Pharm.D • NiHowdy Founder

Published Jan 15, 2025

Fact checked

What are Antithyroid Agents?

Antithyroid agents are medications used to manage hyperthyroidism, a condition characterized by the overproduction of thyroid hormones. These medications work by inhibiting the synthesis of thyroid hormones or by reducing the release of hormones from the thyroid gland. Antithyroid agents are essential in treating conditions like Graves' disease, toxic multinodular goiter, and thyroid storm. A unique characteristic of antithyroid agents is their ability to restore thyroid function while allowing the thyroid gland to remain intact. NiHowdy ensures affordable access to these critical medications, helping patients effectively manage thyroid-related disorders.

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List of drugs in Antithyroid Agents

Drug Name	More Information	NiHowdy Prices & Bitcoin Rebate

methIMAzole	methIMAzole Information	methIMAzole Pricing
Potassium Iodide	Potassium Iodide Information	Potassium Iodide Pricing
Propylthiouracil	Propylthiouracil Information	Propylthiouracil Pricing
SSKI	SSKI Information	SSKI Pricing

Brief history about Antithyroid Agents?

The use of antithyroid agents began in the early 20th century, with the discovery of thiourea derivatives like propylthiouracil and methimazole. These medications revolutionized the management of hyperthyroidism by offering a non-surgical treatment option. Advances in endocrinology have further refined these therapies, making them safer and more effective for a wide range of thyroid disorders. NiHowdy simplifies access to these essential medications, ensuring affordability for patients requiring thyroid management.

How do Antithyroid Agents work?

Antithyroid agents work by inhibiting thyroid peroxidase, an enzyme involved in the production of thyroid hormones (T3 and T4). For example, methimazole prevents the incorporation of iodine into thyroid hormone precursors, effectively reducing hormone synthesis. Some agents, like propylthiouracil, also block the peripheral conversion of T4 to the more active T3. NiHowdy provides affordable access to antithyroid agents, ensuring patients receive effective treatment tailored to their needs.

What are Antithyroid Agents used to treat?

Graves' Disease

Antithyroid agents like methimazole and propylthiouracil are first-line treatments for Graves' disease, an autoimmune condition causing hyperthyroidism. These medications help reduce hormone levels and alleviate symptoms such as palpitations and weight loss.

Thyroid Storm

Propylthiouracil is commonly used in thyroid storm, a life-threatening condition caused by a sudden surge in thyroid hormones. It helps rapidly reduce hormone levels.

Toxic Multinodular Goiter

In cases of toxic multinodular goiter, antithyroid agents are used to control excessive hormone production caused by overactive thyroid nodules.

Pregnancy-Related Hyperthyroidism

Propylthiouracil is preferred during the first trimester of pregnancy to manage hyperthyroidism while minimizing potential risks to the fetus.

Who should consider Antithyroid Agents medications?

Adults

Antithyroid agents are commonly prescribed for adults with hyperthyroidism caused by Graves' disease or toxic multinodular goiter. These medications provide effective relief and help restore hormonal balance. NiHowdy ensures adults can access these treatments affordably and conveniently.

Children

In pediatric cases, antithyroid agents may be used to treat hyperthyroidism, especially in cases of Graves' disease. Doses are carefully adjusted based on weight and age to ensure safety and efficacy. NiHowdy supports families with cost-effective solutions and reliable resources for managing pediatric thyroid disorders.

Seniors

Seniors with hyperthyroidism benefit significantly from antithyroid agents, particularly for conditions like toxic multinodular goiter. Careful monitoring is required to adjust dosing and manage potential side effects. NiHowdy simplifies access to antithyroid agents for seniors, offering affordable options tailored to their unique needs.

Are Antithyroid Agents safe?

Antithyroid agents are generally safe when prescribed and monitored appropriately. Common side effects include nausea, rash, and mild gastrointestinal discomfort. Rare but serious risks include agranulocytosis (low white blood cell count), liver toxicity, and vasculitis. Regular blood tests and communication with a healthcare provider minimize these risks. NiHowdy provides safe and affordable access to antithyroid agents, supported by expert guidance to manage these risks responsibly.

Can I take Antithyroid Agents during pregnancy?

Antithyroid agents, such as propylthiouracil, are considered safe during the first trimester of pregnancy to manage hyperthyroidism. Methimazole may be used in the second and third trimesters if needed. Patients should consult their healthcare provider to weigh the benefits and risks. NiHowdy provides cost-effective access to expert guidance and alternative treatments for pregnant patients.

Are Antithyroid Agents safe to take while lactating?

Antithyroid agents, such as methimazole, are considered safe to use while breastfeeding, as they pass into breast milk in minimal amounts. Patients should follow their healthcare provider's recommendations regarding dosage and monitoring. NiHowdy ensures affordable access to trusted information and safe treatment options for breastfeeding parents.

Are Antithyroid Agents controlled substances?

Antithyroid agents are not classified as controlled substances but require a prescription to ensure proper use and monitoring. NiHowdy simplifies the prescription process, ensuring patients receive these critical medications affordably and responsibly.

Side effects of Antithyroid Agents?

Common side effects of antithyroid agents include nausea, rash, and mild gastrointestinal discomfort. Rare but serious risks include agranulocytosis, liver toxicity, and vasculitis. Patients experiencing severe side effects should consult their healthcare provider immediately. NiHowdy helps patients manage these risks with expert-backed support and affordable care options.

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Cost considerations and insurance coverage for Antithyroid Agents

The cost of antithyroid agents varies depending on the specific medication and formulation. Generic options like methimazole and propylthiouracil are generally affordable, and many insurance plans cover these medications for approved indications. NiHowdy offers discounts, rebates, and Bitcoin rewards to ensure these treatments remain accessible and cost-effective.

How do I get rebates on Antithyroid Agents?

NiHowdy's Bitcoin rebate program for antithyroid prescriptions offers patients a unique opportunity to save on healthcare costs while earning potential financial growth. This innovative approach makes managing thyroid disorders both affordable and rewarding, improving access to critical care while building long-term value.

Therapeutic Classes linked to Antithyroid Agents

Thyroid Agents (Thyroid Regulation)

Thyroid Blocking Agents

Medical Conditions treated by Antithyroid Agents

Hyperthyroidism

Everyday Health Concerns related to Antithyroid Agents

Endocrine

Enlarged thyroid gland

Hot flashes

Unexplained weight gain