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Zovia 1/35 (28)
Zovia 1/35 (generic name: ethynodiol diacetate and ethinyl estradiol) is a combined oral contraceptive pill used to prevent pregnancy. It contains a combination of estrogen (ethinyl estradiol) and progestin (ethynodiol diacetate) that work together to prevent ovulation, alter the uterine lining to prevent implantation, and thicken cervical mucus to block sperm from reaching an egg. Zovia 1/35 also helps regulate menstrual cycles and may reduce the risk of ovarian cysts, acne, and heavy or painful periods.
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Frequently Asked Questions
How soon after starting Zovia 1/35 am I protected against pregnancy?
If you start Zovia on the first day of your period, you are protected immediately. If started on any other day, use backup contraception (e.g., condoms) for the first 7 days.
What should I do if I miss a pill?
If you miss one pill, take it as soon as you remember, and take the next pill at your regular time. If you miss two or more pills, follow the instructions in the package insert and use backup contraception for 7 days.
Can Zovia help with acne?
Yes, Zovia may help reduce acne for some women by regulating hormones, but it is not specifically approved for acne treatment.
Can I use Zovia if I have migraines?
If you experience migraines with aura, Zovia may not be recommended due to an increased risk of stroke. Consult your healthcare provider for advice.
Can Zovia cause weight gain?
Some women may experience weight changes while using Zovia, but significant weight gain is uncommon. Most women do not experience substantial changes in weight.
Comprehensive Drug Guide
How Does Zovia 1/35 (28) Work?
- Inhibiting ovulation: Prevents the release of an egg from the ovaries.
- Thickening cervical mucus: Makes it difficult for sperm to enter the uterus.
- Altering the uterine lining: Makes it less suitable for implantation of a fertilized egg.
Common Dosages
- 21 active tablets: 1 mg ethynodiol diacetate / 35 mcg ethinyl estradiol.
- 7 placebo (inactive) tablets: Taken during the last week of the cycle.
Typical Dosing
- Take one active tablet daily for 21 consecutive days, followed by one inactive tablet daily for 7 days.
- Begin a new pack after finishing the 28 tablets, regardless of whether bleeding has started or stopped.
- Try to take the pill at the same time every day to maintain its effectiveness.
Typical Dosing
FDA Approved Indications
- Prevention of pregnancy in women who choose oral contraceptives as their method of birth control.
Who Shouldn't Take Zovia 1/35 (28)?
- History of thromboembolic events (e.g., deep vein thrombosis, pulmonary embolism).
- Uncontrolled hypertension or severe cardiovascular conditions.
- Liver disease or liver tumors.
- Breast cancer or other hormone-sensitive cancers.
- Smokers over 35 years of age, due to an increased risk of cardiovascular events.
Advice From The Pharmacist
- Take Zovia at the same time every day to maintain consistent hormone levels and ensure effective contraception.
- If you miss a dose, take it as soon as you remember. If you miss two or more pills, follow the instructions in your pack’s leaflet and use backup contraception for the next 7 days.
- If vomiting or diarrhea occurs within a few hours of taking a pill, treat it as a missed dose and take another pill as soon as possible.
- Avoid smoking while on Zovia, as it increases the risk of serious cardiovascular side effects, particularly in women over 35 years old.
Side Effects of Zovia 1/35 (28)
Common Side Effects
- Nausea
- Breast tenderness
- Headache
- Weight changes
- Breakthrough bleeding (spotting)
Uncommon/Severe Side Effects
- Blood clots (deep vein thrombosis, pulmonary embolism)
- Stroke
- Heart attack
- Liver problems (yellowing of the skin or eyes)
- Severe allergic reactions (rash, swelling, difficulty breathing)
Risks and Warnings of Zovia 1/35 (28)
- Blood Clot Risk: Combined oral contraceptives like Zovia increase the risk of blood clots, especially in women who smoke, are over 35, or have other risk factors such as obesity or family history of clotting disorders.
- Cardiovascular Risk: There is an increased risk of stroke, heart attack, and hypertension in women who use oral contraceptives, particularly in smokers over the age of 35.
- Liver Problems: Long-term use of hormonal contraceptives has been associated with an increased risk of liver tumors and other liver-related issues.
Interactions with Zovia 1/35 (28)
Common Drug Interactions
- Antibiotics: Some antibiotics (e.g., rifampin) may reduce the effectiveness of Zovia, requiring backup contraception during and for 7 days after treatment.
- Anticonvulsants: Medications like phenytoin and carbamazepine may decrease the effectiveness of hormonal contraceptives.
- St. John’s Wort: This herbal supplement can reduce the effectiveness of Zovia.
Alternatives to Zovia 1/35 (28)
- Loestrin Fe: A low-dose combination oral contraceptive similar to Zovia.
- Ortho Tri-Cyclen: A combination oral contraceptive that can also help manage acne.
- NuvaRing: A vaginal ring that releases hormones to prevent pregnancy.
- Depo-Provera: A progestin-only injectable birth control given every three months.
