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Ziclocin
Ziclocin (clindamycin) is a topical antibiotic used to treat bacterial infections of the skin, particularly acne vulgaris. It works by stopping the growth of bacteria responsible for causing acne, which helps reduce inflammation, swelling, and the formation of pimples. Clindamycin is part of the lincosamide antibiotic family and is effective against a range of bacterial species.
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Frequently Asked Questions
How long does it take for Ziclocin to work?
Ziclocin may start showing improvement in acne symptoms within a few weeks, but it can take 8-12 weeks to see the full effect. Continue using it as directed for the best results.
Can I use makeup while using Ziclocin?
Yes, you can use makeup while using Ziclocin, but choose non-comedogenic (non-pore-clogging) products to avoid worsening your acne. Make sure to apply Ziclocin first and allow it to dry before applying makeup.
What should I do if I miss a dose?
If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose.
Can I use Ziclocin with other acne treatments?
It depends on the treatments. Some combinations, such as benzoyl peroxide and clindamycin, may be recommended by your healthcare provider. However, always consult your doctor before combining treatments to avoid skin irritation.
Can Ziclocin be used for other skin infections?
Ziclocin is typically used to treat acne, but topical clindamycin may sometimes be prescribed for other bacterial skin infections. Consult your healthcare provider for specific use cases.
Comprehensive Drug Guide
How Does Ziclocin Work?
Ziclocin (clindamycin) works by inhibiting bacterial protein synthesis. It binds to the 50S ribosomal subunit of bacteria, preventing the bacteria from producing essential proteins needed for growth and replication. This action stops the spread of acne-causing bacteria on the skin and helps to clear acne breakouts.
Common Dosages
- Topical solution, gel, or lotion: Typically 1% clindamycin.
Typical Dosing
- For acne vulgaris, Ziclocin is usually applied twice daily (morning and evening) to the affected areas after cleansing the skin.
- The usual concentration is 1% clindamycin, and it is important to follow your healthcare provider’s instructions regarding the duration of treatment.
Typical Dosing
FDA Approved Indications
- Acne vulgaris, particularly moderate to severe cases where topical antibiotics are indicated.
Who Shouldn't Take Ziclocin?
- A known hypersensitivity to clindamycin or lincomycin.
- A history of ulcerative colitis, enteritis, or antibiotic-associated colitis, as topical clindamycin can be absorbed systemically and may exacerbate these conditions.
Advice From The Pharmacist
- Before applying Ziclocin, cleanse and dry the affected area of the skin thoroughly.
- Apply a thin layer of the gel, solution, or lotion to the affected area. Avoid getting the medication in the eyes, mouth, or other mucous membranes. If accidental contact occurs, rinse thoroughly with water.
- Use Ziclocin regularly for best results, even if your acne improves. Acne treatment may take several weeks to show full benefits, so continue using the medication as prescribed by your healthcare provider.
- Avoid excessive sun exposure or use of tanning beds, as clindamycin may make your skin more sensitive to sunlight. Apply sunscreen if you need to be outdoors.
- Do not apply other acne medications, such as benzoyl peroxide or tretinoin, unless advised by your healthcare provider, as this may increase skin irritation.
Side Effects of Ziclocin
Common Side Effects
- Skin irritation, such as redness, dryness, or peeling
- Burning or itching at the application site
- Oily skin
Uncommon/Severe Side Effects
- Severe allergic reactions (swelling, rash, difficulty breathing)
- Diarrhea or colitis, as some clindamycin can be absorbed systemically and may cause antibiotic-associated colitis or diarrhea.
Risks and Warnings of Ziclocin
- Antibiotic Resistance: Prolonged use of topical antibiotics like Ziclocin can lead to bacterial resistance. If your acne does not improve after a certain period, discuss with your healthcare provider if alternative treatments are needed.
- Colitis: While uncommon, clindamycin may be absorbed into the bloodstream and can lead to severe diarrhea or Clostridium difficile-associated colitis. Discontinue use if severe diarrhea occurs and consult your healthcare provider immediately.
Interactions with Ziclocin
Common Drug Interactions
- There are no significant drug interactions with topical Ziclocin, but patients should inform their healthcare provider of any other topical or systemic medications they are using. Avoid combining it with other skin treatments unless recommended by your doctor to reduce the risk of irritation.
Alternatives to Ziclocin
- Benzoyl peroxide: A common over-the-counter treatment for acne that works by killing bacteria and helping to clear pores.
- Tretinoin (Retin-A): A topical retinoid used to treat acne by promoting skin cell turnover and preventing clogged pores.
- Erythromycin topical: Another topical antibiotic used to treat acne, though clindamycin is generally more effective.
