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Zetonna
Zetonna (generic name: ciclesonide) is a nasal corticosteroid used to treat the symptoms of allergic rhinitis, including nasal congestion, sneezing, runny nose, and itching. It works by reducing inflammation in the nasal passages, helping to relieve these symptoms. Zetonna is administered as a nasal aerosol spray and is commonly prescribed for both seasonal and perennial allergic rhinitis in adults and children aged 12 years and older.
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Frequently Asked Questions
How long does it take for Zetonna to start working?
Zetonna may start providing symptom relief within a few days, but it may take up to a week to feel the full effects. Continue using it daily for the best results.
Can I use Zetonna if I have a cold or sinus infection?
You should avoid using Zetonna if you have an untreated nasal infection. Consult your healthcare provider if you develop a sinus infection while using the medication.
What should I do if I miss a dose of Zetonna?
If you miss a dose, take it as soon as you remember. If it’s close to the time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to make up for a missed dose.
Can Zetonna be used in children?
Zetonna is approved for use in children aged 12 years and older for the treatment of allergic rhinitis. It is not recommended for younger children.
Is long-term use of Zetonna safe?
Zetonna is generally safe for long-term use, but like other corticosteroids, prolonged use may increase the risk of nasal infections, glaucoma, or cataracts. Regular monitoring by your healthcare provider is recommended.
Comprehensive Drug Guide
How Does Zetonna Work?
Zetonna contains ciclesonide, which is a corticosteroid that works by suppressing inflammation in the nasal passages. By reducing the activity of inflammatory cells and mediators (e.g., histamine, leukotrienes), Zetonna helps alleviate the symptoms of allergic rhinitis, such as nasal congestion, sneezing, and itching.
Common Dosages
- 37 mcg nasal aerosol spray
Typical Dosing
- The usual recommended dose of Zetonna is one spray in each nostril once daily (total daily dose of 74 mcg).
- Each canister provides 60 sprays and should be primed before the first use by releasing 3 test sprays into the air.
Typical Dosing
FDA Approved Indications
- Treatment of nasal symptoms of allergic rhinitis (seasonal and perennial) in adults and children aged 12 years and older.
Who Shouldn't Take Zetonna?
- Known hypersensitivity to ciclesonide or any of the ingredients in the formulation.
- Untreated nasal infections, such as bacterial, fungal, or viral infections, as corticosteroids may worsen these conditions.
Advice From The Pharmacist
- Shake the canister well before each use and make sure to prime it by spraying into the air before using it for the first time or if it has not been used for a while.
- Avoid spraying Zetonna into your eyes or mouth, as it is intended for nasal use only.
- Blow your nose before using the spray to ensure that the medication reaches the inflamed nasal tissues effectively.
- If you are using more than one nasal spray, wait at least 5 minutes between different products.
- It may take several days to a week to feel the full effects of Zetonna. Use it regularly for the best results.
Side Effects of Zetonna
Common Side Effects
- Nosebleeds
- Headache
- Nasal discomfort or dryness
- Sneezing
Uncommon/Severe Side Effects
- Severe allergic reactions (rash, swelling, difficulty breathing)
- Nasal ulcers or perforation (a hole in the septum)
- Worsening of existing infections, such as nasal, sinus, or respiratory infections
- Glaucoma or cataracts (with long-term use of corticosteroids)
Risks and Warnings of Zetonna
- Nasal Infections: Long-term use of nasal corticosteroids like Zetonna can increase the risk of nasal infections, such as fungal or bacterial infections. Patients should be monitored for signs of nasal infections, such as persistent nasal discomfort or sores.
- Nosebleeds and Nasal Irritation: Zetonna can cause nosebleeds or nasal discomfort in some patients. If these symptoms persist or worsen, consult your healthcare provider.
- Vision Problems: Long-term use of corticosteroids may increase the risk of glaucoma or cataracts. Regular eye exams are recommended for patients on prolonged corticosteroid therapy.
- Immunosuppression: Corticosteroids can suppress the immune system, making patients more susceptible to infections. Avoid contact with people who have contagious illnesses (e.g., chickenpox or measles).
Interactions with Zetonna
Common Drug Interactions
- Other corticosteroids: Using multiple corticosteroid-containing medications (e.g., inhalers, creams, or pills) can increase the risk of side effects, such as adrenal suppression or weakened immune response.
- Medications that weaken the immune system: Be cautious when using Zetonna alongside immunosuppressive medications, as it can increase the risk of infections.
Alternatives to Zetonna
- Fluticasone (Flonase): Another nasal corticosteroid commonly used to treat allergic rhinitis.
- Mometasone (Nasonex): Another corticosteroid nasal spray used for seasonal and perennial allergic rhinitis.
- Budesonide (Rhinocort Aqua): A nasal corticosteroid spray used to relieve nasal symptoms associated with allergies.
