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Zeruvia
Zeruvia (sertaconazole nitrate) is a topical antifungal medication used to treat tinea pedis, also known as athlete’s foot. It belongs to the imidazole class of antifungals and works by inhibiting the growth of fungi that cause skin infections. Zeruvia is effective at treating the itching, redness, and discomfort associated with fungal infections, particularly in the skin between the toes.
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Frequently Asked Questions
How long does it take for Zeruvia to work?
You may begin to see improvement in symptoms within a few days of using Zeruvia, but the full treatment course typically lasts 4 weeks to ensure the infection is fully cleared.
Can I use Zeruvia for other fungal infections, like jock itch?
Zeruvia is primarily indicated for athlete’s foot, but it may be effective against other fungal infections. Consult your healthcare provider for appropriate use in other areas.
What should I do if my symptoms don’t improve?
If your symptoms don’t improve after 4 weeks of consistent use, or if they worsen, contact your healthcare provider for further evaluation and treatment.
Can I cover the affected area with a bandage after applying Zeruvia?
You should avoid covering the treated area with a bandage or occlusive dressing unless specifically instructed by your doctor, as this can trap moisture and may promote further fungal growth.
Can I use Zeruvia while pregnant or breastfeeding?
The safety of Zeruvia during pregnancy or breastfeeding has not been fully established. Consult your healthcare provider before using this medication if you are pregnant or breastfeeding.
Comprehensive Drug Guide
How Does Zeruvia Work?
Sertaconazole, the active ingredient in Zeruvia, inhibits the synthesis of ergosterol, a key component of fungal cell membranes. By blocking ergosterol production, the integrity of the fungal cell membrane is compromised, which ultimately leads to the death of the fungal cells and the resolution of the infection.
Common Dosages
- Zeruvia is available as a 2% topical cream, typically provided in tubes for external use.
Typical Dosing
- Apply a thin layer of the cream to the affected area twice daily (morning and evening) for 4 weeks or as directed by your healthcare provider.
- Be sure to cover the affected areas completely, including the spaces between the toes.
Typical Dosing
FDA Approved Indications
- The treatment of tinea pedis (athlete’s foot), particularly in infections involving the areas between the toes.
Who Shouldn't Take Zeruvia?
- Hypersensitivity to sertaconazole, other imidazole antifungals, or any component of the formulation.
Advice From The Pharmacist
- Apply Zeruvia only to the affected areas of the skin. Wash and dry the affected area before applying the cream, ensuring the skin is clean and dry.
- Avoid contact with the eyes, nose, mouth, or any mucous membranes.
- Continue using Zeruvia for the full course of treatment, even if the symptoms improve early. Stopping treatment too soon can cause the infection to return.
- If you miss a dose, apply it as soon as you remember. If it is close to your next dose, skip the missed dose and continue with your regular schedule. Do not double up doses.
Side Effects of Zeruvia
Common Side Effects
- Mild irritation or redness at the application site
- Dry or flaky skin
- Itching
Uncommon/Severe Side Effects
- Severe skin irritation or burning
- Allergic reactions (rash, swelling, difficulty breathing)
Risks and Warnings of Zeruvia
- Allergic Reactions: In rare cases, patients may experience severe allergic reactions to sertaconazole. If you develop symptoms such as rash, swelling, or difficulty breathing, discontinue use and seek immediate medical attention.
- External Use Only: Zeruvia is for topical use only and should not be ingested or applied to mucous membranes. Avoid contact with the eyes, nose, and mouth.
Interactions with Zeruvia
Common Drug Interactions
- No significant drug interactions are expected with topical use of Zeruvia. However, always inform your healthcare provider about any other medications or skincare products you are using to avoid potential reactions.
Alternatives to Zeruvia
- Clotrimazole (Lotrimin): A topical antifungal cream used for treating athlete’s foot and other fungal infections.
- Terbinafine (Lamisil): A topical or oral antifungal treatment for tinea pedis and other fungal infections.
- Miconazole (Micatin): A topical antifungal cream used for the treatment of fungal skin infections.
