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Vanoxide-HC

Vanoxide-HC is a topical combination medication that contains benzoyl peroxide and hydrocortisone. It is primarily used to treat acne and certain skin conditions associated with inflammation and redness. Benzoyl peroxide works as an antibacterial agent that helps reduce acne-causing bacteria and unclog pores, while hydrocortisone is a mild corticosteroid that reduces inflammation and redness.



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Frequently Asked Questions

How long does it take to see results with Vanoxide-HC?
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You may start noticing improvement in your skin after a few weeks of use. Full benefits may take 6 to 8 weeks of regular use.

Can I use Vanoxide-HC on other parts of my body?
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Yes, Vanoxide-HC can be applied to acne-prone areas of the body, such as the back, chest, or shoulders. However, avoid using it on large areas unless directed by your healthcare provider.

Can I wear makeup while using Vanoxide-HC?
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Yes, you can wear makeup, but choose non-comedogenic (non-pore clogging) products to avoid further irritation or breakouts.

Can Vanoxide-HC be used during pregnancy?
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Consult your healthcare provider before using Vanoxide-HC during pregnancy, as certain topical medications may not be recommended.

What should I do if my skin becomes too dry or irritated?
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If your skin becomes excessively dry or irritated, reduce the frequency of application or temporarily stop using the product. You can also use a gentle, fragrance-free moisturizer to help with dryness. If symptoms persist, contact your healthcare provider.

Comprehensive Drug Guide

How Does Vanoxide-HC Work?

  • Benzoyl peroxide works by releasing oxygen into the pores, creating an environment that kills acne-causing bacteria and helps to reduce breakouts. It also helps remove dead skin cells and excess oils that contribute to clogged pores.
  • Hydrocortisone is a corticosteroid that helps reduce inflammation, redness, and swelling. It works by suppressing the immune system's inflammatory response in the skin.


Common Dosages

  • Benzoyl peroxide (5% or 10%) and hydrocortisone (1%) topical gel or cream.

Typical Dosing

  • Apply a thin layer of Vanoxide-HC to the affected area(s) once or twice daily, depending on the severity of the acne or skin condition and as directed by your healthcare provider.
  • Start with a once-daily application, and increase to twice daily if needed and tolerated.


Typical Dosing

FDA Approved Indications

  • Mild to moderate acne.
  • Inflammatory skin conditions associated with acne, such as redness and swelling.


Who Shouldn't Take Vanoxide-HC?

  • Hypersensitivity to benzoyl peroxide, hydrocortisone, or any component of the formulation.
  • Severe or widespread acne, unless recommended by a healthcare provider.
  • Rosacea or perioral dermatitis, as corticosteroids can worsen these conditions.


Advice From The Pharmacist

  • Avoid contact with the eyes, mouth, and mucous membranes, as the combination of benzoyl peroxide and hydrocortisone may cause irritation.
  • Apply the medication to clean, dry skin, and use a gentle cleanser before application to reduce the risk of further irritation.
  • Benzoyl peroxide can bleach clothing, towels, and hair, so be careful when applying it to avoid contact with fabrics.
  • If your skin becomes excessively dry, irritated, or red, reduce the frequency of application or discontinue use and contact your healthcare provider.
  • Protect your skin from excessive sun exposure while using Vanoxide-HC, as benzoyl peroxide can increase your skin's sensitivity to sunlight.


Side Effects of Vanoxide-HC

Common Side Effects

  • Dryness or peeling of the skin
  • Mild skin irritation or redness
  • Itching or stinging at the application site


Uncommon/Severe Side Effects

  • Severe skin irritation or burning
  • Allergic reactions (rash, swelling, difficulty breathing)
  • Skin thinning (with prolonged use of hydrocortisone)


Risks and Warnings of Vanoxide-HC

  • Skin Irritation: Both benzoyl peroxide and hydrocortisone can cause skin irritation, especially when used on sensitive skin. If severe irritation occurs, discontinue use and consult your healthcare provider.
  • Long-Term Use of Corticosteroids: Hydrocortisone should not be used for extended periods, as it can lead to skin thinning, stretch marks, or delayed wound healing, especially on sensitive areas like the face.
  • Photosensitivity: Benzoyl peroxide can make your skin more sensitive to sunlight, so it is important to use sunscreen and limit direct sun exposure while using this medication.


Interactions with Vanoxide-HC

Common Drug Interactions

  • Other topical acne treatments: Using multiple acne treatments (such as retinoids or salicylic acid) alongside Vanoxide-HC may increase skin irritation or dryness.
  • Cosmetics and skin products: Avoid using harsh or abrasive skin products, as they may worsen dryness and irritation when used with Vanoxide-HC.


Alternatives to Vanoxide-HC

  • Benzoyl peroxide (without hydrocortisone): Often used alone for treating acne, available over-the-counter or by prescription.
  • Clindamycin-benzoyl peroxide gel: An alternative combination for treating acne, combining an antibiotic (clindamycin) with benzoyl peroxide.
  • Topical retinoids (tretinoin, adapalene): Medications used for acne treatment that promote skin cell turnover and prevent clogged pores.