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Tudorza Pressair
Tudorza Pressair (generic name: aclidinium bromide) is a prescription inhaler used to treat chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema. It is a long-acting muscarinic antagonist (LAMA) that works by relaxing the muscles around the airways in the lungs, making it easier to breathe. Tudorza Pressair is used for maintenance treatment to reduce flare-ups of COPD symptoms and improve lung function over time.
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Frequently Asked Questions
How long does it take for Tudorza Pressair to work?
Tudorza Pressair starts to work within a few hours, but it is intended for long-term control of COPD symptoms. It may take several weeks of regular use to experience the full benefits.
Can I use Tudorza Pressair for sudden breathing problems?
No, Tudorza Pressair is not a rescue inhaler. You should use a fast-acting inhaler, such as albuterol, for sudden breathing problems or COPD exacerbations.
Can I stop using Tudorza Pressair if my symptoms improve?
Do not stop using Tudorza Pressair without consulting your healthcare provider. It is important to use the medication regularly to maintain control of COPD symptoms.
Does Tudorza Pressair interact with other inhalers?
You can use other types of inhalers, such as short-acting beta-agonists (SABAs) like albuterol, alongside Tudorza Pressair, but avoid using other anticholinergic inhalers, as they may increase the risk of side effects.
How do I know if I’ve used Tudorza Pressair correctly?
After inhaling, you should hear a "click," and the green control window on the inhaler should turn red, confirming that you’ve taken the dose correctly. If this doesn’t happen, try again and consult your healthcare provider if you have difficulty using the inhaler.
Comprehensive Drug Guide
How Does Tudorza Pressair Work?
Tudorza Pressair contains aclidinium bromide, which blocks muscarinic receptors in the smooth muscles of the airways. By inhibiting these receptors, aclidinium prevents bronchoconstriction (narrowing of the airways), allowing the muscles in the airways to relax. This helps improve airflow and reduces COPD symptoms, such as shortness of breath, coughing, and wheezing.
Common Dosages
- Each inhalation of Tudorza Pressair delivers 400 mcg of aclidinium bromide. It is designed for twice-daily use.
Typical Dosing
- The usual recommended dose is one inhalation twice daily (once in the morning and once in the evening), approximately 12 hours apart.
- Tudorza Pressair is not intended for rescue use (to relieve sudden breathing problems). Patients should carry a short-acting inhaler, like albuterol, for acute symptoms.
Typical Dosing
FDA Approved Indications
- Maintenance treatment of chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema.
Who Shouldn't Take Tudorza Pressair?
- Severe hypersensitivity to aclidinium bromide or any component of the formulation.
- Acute bronchospasm or sudden breathing problems, as it is not a rescue inhaler.
Advice From The Pharmacist
- Use Tudorza Pressair exactly as prescribed—twice daily—even if you are feeling well. This is a long-term maintenance treatment, not a rescue inhaler.
- If you miss a dose, take it as soon as you remember, unless it is close to the time of your next dose. Do not double up on doses to make up for a missed one.
- Ensure proper inhalation technique to get the full benefit of the medication. You should hear a "click" and see a green control window change to red, confirming that you have taken a full dose.
- Clean the inhaler regularly by wiping the mouthpiece with a dry tissue or cloth.
- Store Tudorza Pressair at room temperature, and keep it in a dry place away from moisture.
Side Effects of Tudorza Pressair
Common Side Effects
- Cough or throat irritation
- Headache
- Nasal congestion or runny nose
- Dry mouth
Uncommon/Severe Side Effects
- Paradoxical bronchospasm (worsening of breathing immediately after use)
- Glaucoma symptoms (eye pain, blurred vision, halos around lights)
- Urinary retention (difficulty urinating, painful urination)
Risks and Warnings of Tudorza Pressair
- Paradoxical Bronchospasm: Although rare, some patients may experience worsening of breathing symptoms immediately after using Tudorza Pressair. If this occurs, discontinue use and seek medical attention immediately.
- Narrow-Angle Glaucoma: Tudorza Pressair may worsen symptoms of narrow-angle glaucoma. Patients with a history of glaucoma should use the medication with caution and report any visual disturbances to their healthcare provider.
- Urinary Retention: Tudorza Pressair can cause or worsen urinary retention, particularly in men with prostate enlargement or bladder problems. Contact your healthcare provider if you experience difficulty urinating.
Interactions with Tudorza Pressair
Common Drug Interactions
- Anticholinergic medications: Combining Tudorza Pressair with other anticholinergic drugs (such as tiotropium or ipratropium) can increase the risk of side effects, such as dry mouth, constipation, or urinary retention.
- Beta-blockers: These medications, commonly used for heart conditions, can reduce the effectiveness of Tudorza Pressair in controlling COPD symptoms.
Alternatives to Tudorza Pressair
- Spiriva (tiotropium): A long-acting muscarinic antagonist (LAMA) used to treat COPD with once-daily dosing.
- Incruse Ellipta (umeclidinium): Another LAMA for the maintenance treatment of COPD.
- Symbicort (budesonide/formoterol): A combination inhaler containing a corticosteroid and a long-acting beta-agonist (LABA) for COPD.
- Advair (fluticasone/salmeterol): A combination inhaler that provides both an inhaled corticosteroid and a long-acting beta-agonist for COPD maintenance.
