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Trumenba
Trumenba is a meningococcal group B vaccine that helps protect against Neisseria meningitidis serogroup B bacteria, which can cause life-threatening infections such as meningitis and sepsis. Meningococcal infections can spread rapidly and cause severe damage to the brain, spinal cord, and bloodstream. Trumenba stimulates the immune system to produce antibodies that help protect against future infection by this bacteria.
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Frequently Asked Questions
Who should receive the Trumenba vaccine?
Trumenba is recommended for individuals aged 10 to 25 years to help prevent invasive meningococcal B disease. It may also be recommended for individuals outside this age range if they are at increased risk due to an outbreak or underlying medical conditions.
Can Trumenba be given with other vaccines?
Yes, Trumenba can be administered alongside other vaccines, but it should be injected into a different site. Inform your healthcare provider if you are receiving other vaccines at the same time.
What should I do if I miss a dose of Trumenba?
If you miss a dose, contact your healthcare provider to reschedule. It’s important to complete the full vaccination series to achieve the best protection.
How long does the protection from Trumenba last?
The duration of protection from Trumenba is not fully known, but completing the recommended dosing schedule provides strong immunity. Your healthcare provider may provide more information based on your specific risk factors.
Can Trumenba cause meningitis?
No, Trumenba is not a live vaccine, and it cannot cause meningitis. It helps your body build immunity to protect against meningococcal B infections.
Comprehensive Drug Guide
How Does Trumenba Work?
Trumenba contains proteins from the outer membrane of Neisseria meningitidis serogroup B bacteria. When injected, it triggers the body’s immune system to produce antibodies against these bacterial proteins. These antibodies help to prevent future infections by recognizing and attacking the bacteria if the individual is exposed.
Common Dosages
- Two-dose series: One injection followed by a second injection 6 months later.
- Three-dose series: One injection followed by a second injection 1-2 months later, and a third injection at 6 months. This series is typically recommended for those at increased risk of meningococcal B disease (such as during an outbreak or for individuals with certain medical conditions).
Typical Dosing
- Two-dose series: Administer the first dose, followed by the second dose 6 months later.
- Three-dose series: Administer the first dose, followed by the second dose 1 to 2 months later, and the third dose 6 months after the first dose.
- The injection is administered intramuscularly (usually in the upper arm).
Typical Dosing
FDA Approved Indications
- Prevention of invasive meningococcal disease caused by Neisseria meningitidis serogroup B in individuals 10 through 25 years of age.
Who Shouldn't Take Trumenba?
- Known hypersensitivity to any component of the vaccine, including previous severe allergic reactions to Trumenba or other meningococcal vaccines.
Advice From The Pharmacist
- Trumenba is given as an injection by a healthcare provider, so ensure you complete the full vaccination series to get the best protection.
- Common side effects like pain at the injection site, fatigue, and mild fever are normal and typically go away after a day or two.
- Notify your healthcare provider if you have a history of allergic reactions to vaccines or if you experience unusual or severe side effects after the injection.
Side Effects of Trumenba
Common Side Effects
- Pain, redness, or swelling at the injection site
- Fatigue
- Headache
- Muscle or joint pain
- Fever
Uncommon/Severe Side Effects
- Severe allergic reactions (e.g., anaphylaxis)
- Fainting or dizziness (typically right after the injection)
Risks and Warnings of Trumenba
- Allergic Reactions: Although rare, some individuals may experience severe allergic reactions to Trumenba. Seek immediate medical attention if you experience difficulty breathing, swelling of the face or throat, or severe rash.
- Syncope (Fainting): Some individuals may faint after receiving an injection, especially adolescents. Patients should sit or lie down during and for 15 minutes after receiving the vaccine to reduce the risk of fainting and injury.
Interactions with Trumenba
Common Drug Interactions
- Other Vaccines: Trumenba can be administered alongside other vaccines but should be given at a different injection site. Always inform your healthcare provider about all the vaccines and medications you are receiving.
Alternatives to Trumenba
- Bexsero: Another meningococcal group B vaccine that is given as a two-dose series. It is also used to protect against meningococcal serogroup B disease.
- Menveo, Menactra: Meningococcal vaccines that protect against serogroups A, C, W, and Y but do not protect against serogroup B.
