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Triesence
Triesence (triamcinolone acetonide) is a steroid medication used primarily for the treatment of eye inflammation. It is an injectable corticosteroid indicated for various ophthalmic conditions, including uveitis, ocular inflammatory diseases, and to reduce inflammation following ocular surgery. Triesence is also used as a diagnostic aid during vitrectomy procedures to enhance visualization of the vitreous. The medication works by reducing inflammation in the eye, which can help prevent damage and preserve vision.
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Frequently Asked Questions
How long does it take for Triesence to work?
You may notice improvement in your eye symptoms within a few days of the injection, although full effects may take a couple of weeks.
How long do the effects of Triesence last?
The effects of a single Triesence injection can last anywhere from several weeks to months, depending on the condition being treated and the individual’s response.
Can Triesence cause blurred vision?
Yes, blurred vision is a common side effect after an injection, but it usually resolves within a few days. If blurred vision persists or worsens, contact your healthcare provider.
Can I drive after receiving a Triesence injection?
It is recommended to avoid driving immediately after the injection, as your vision may be temporarily blurred. Wait until your vision has cleared before resuming activities that require clear eyesight.
What should I do if I experience pain or swelling after a Triesence injection?
Mild discomfort is normal after the injection, but if you experience severe pain, swelling, or sudden changes in vision, contact your eye doctor immediately, as these could be signs of a serious complication.
Comprehensive Drug Guide
How Does Triesence Work?
Triamcinolone acetonide works by inhibiting the release of pro-inflammatory substances like cytokines and prostaglandins in the body. This reduction in inflammation helps to relieve swelling, redness, and pain in the eyes. When injected into the eye, Triesence targets the underlying inflammation in conditions like uveitis or helps visualize the vitreous during vitrectomy.
Common Dosages
- 40 mg/mL injectable suspension.
Typical Dosing
- For uveitis and other inflammatory conditions, the typical dose is 4 mg to 40 mg injected directly into the posterior segment of the eye.
- For vitrectomy, Triesence is used in a single dose to enhance the visualization of the vitreous during the procedure.
Typical Dosing
FDA Approved Indications
- Treatment of ocular inflammation, including non-infectious uveitis.
- Visualization of the vitreous during vitrectomy surgery.
- Treatment of sympathetic ophthalmia and ocular inflammatory conditions unresponsive to topical treatments.
Who Shouldn't Take Triesence?
- Active ocular infections, including fungal, viral, or bacterial infections.
- Known hypersensitivity to triamcinolone acetonide or any components of the suspension.
Advice From The Pharmacist
- Triesence is administered by an eye care specialist in a clinical setting, usually via intravitreal injection.
- After the injection, you may experience blurred vision or discomfort in the treated eye. These symptoms should subside over time, but contact your doctor if they persist or worsen.
- Avoid rubbing your eyes or putting pressure on the treated eye after the injection.
- Follow up with your doctor regularly to monitor your response to the treatment and check for any side effects.
Side Effects of Triesence
Common Side Effects
- Blurred vision
- Eye discomfort or redness
- Increased intraocular pressure (IOP)
- Eye floaters
Uncommon/Severe Side Effects
- Infection inside the eye (endophthalmitis), with symptoms like increased pain, redness, or vision changes.
- Cataract formation, particularly with long-term use.
- Glaucoma or increased intraocular pressure, which may require additional treatment.
- Retinal detachment (rare but serious).
Risks and Warnings of Triesence
- Increased Intraocular Pressure (IOP): Triesence can raise eye pressure, which may lead to glaucoma. Regular monitoring of eye pressure is necessary after injections.
- Cataracts: Long-term use of injectable corticosteroids like Triesence may lead to cataract development, which could affect vision and may require surgery.
- Infection Risk: Any injection into the eye carries a risk of infection (endophthalmitis). If you experience symptoms such as severe eye pain, swelling, or vision loss, seek immediate medical attention.
- Retinal Detachment: Though rare, intravitreal injections can cause retinal detachment. Symptoms include a sudden increase in floaters or a curtain-like shadow over part of the vision.
Interactions with Triesence
Common Drug Interactions
- Other corticosteroids: Use of systemic or topical corticosteroids with Triesence can increase the risk of side effects like increased IOP or immunosuppression.
- Anticoagulants (e.g., warfarin): Corticosteroids may increase the risk of bleeding when used with anticoagulant medications.
Alternatives to Triesence
- Ozurdex (Dexamethasone Intravitreal Implant): A corticosteroid implant used for long-term treatment of ocular inflammation and macular edema.
- Kenalog (Triamcinolone Acetonide Injectable): Another form of triamcinolone used for treating ocular inflammation.
- Iluvien (Fluocinolone Acetonide Implant): A corticosteroid implant used for diabetic macular edema and non-infectious uveitis.