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Tessalon Perles

Tessalon Perles (generic name: benzonatate) is a non-narcotic cough suppressant used to relieve coughing associated with conditions like the common cold, bronchitis, or other respiratory conditions. Benzonatate works by numbing the throat and lungs, reducing the cough reflex. It is an effective treatment for patients seeking relief from persistent coughing without the sedative or addictive risks associated with narcotic cough medicines.

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Frequently Asked Questions

How long does it take for Tessalon Perles to work?
Open FAQClose FAQ

Tessalon Perles usually begin to work within 15 to 20 minutes after ingestion, providing relief from coughing for 4 to 8 hours.

Can I take Tessalon Perles with other cold medications?
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Yes, but caution should be exercised when combining with other medications containing cough suppressants or sedatives. Always check with your healthcare provider before combining medications.

Can Tessalon Perles be used for children?
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Tessalon Perles should not be used in children under the age of 10, as accidental ingestion can result in severe and potentially fatal side effects.

Can I chew or dissolve Tessalon Perles?
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No, Tessalon Perles must be swallowed whole. Chewing or dissolving the capsules can cause numbing of the mouth and throat, which can lead to choking or severe adverse effects.

What should I do if I accidentally chew a Tessalon Perle?
Open FAQClose FAQ

If you accidentally chew or dissolve a capsule, rinse your mouth with water and avoid swallowing until the numbness subsides. Seek medical attention if you experience difficulty breathing or swallowing.

Comprehensive Drug Guide

How Does Tessalon Perles Work?

Benzonatate works by anesthetizing (numbing) the stretch receptors in the lungs, airways, and pleura, reducing the reflex to cough. This action allows patients to experience relief from persistent, nonproductive coughs, making it easier to breathe and rest.

Common Dosages

  • 100 mg capsules
  • 200 mg capsules

Typical Dosing

  • For adults and children over 10 years old: The typical dose is 100 mg to 200 mg taken three times a day as needed for cough. Do not exceed 600 mg per day.


Typical Dosing

FDA Approved Indications

  • Symptomatic relief of cough due to common cold or respiratory tract infections such as bronchitis or pneumonia.

Who Shouldn't Take Tessalon Perles?

  • Known hypersensitivity to benzonatate or related compounds.
  • Children under 10 years old, as accidental ingestion can lead to serious or fatal side effects.

Advice From The Pharmacist

  • Swallow Tessalon Perles whole. Do not chew or dissolve the capsules, as this can release the medication in the mouth, causing numbness in the mouth or throat, which can lead to choking or severe reactions.
  • Do not exceed the prescribed dose, as higher doses can increase the risk of severe side effects, including seizures or cardiac arrest.
  • If you miss a dose, take it as soon as you remember unless it is close to the time of your next dose. In that case, skip the missed dose and continue your regular schedule.
  • Keep Tessalon Perles out of reach of children, as accidental ingestion can be life-threatening.
  • Avoid alcohol or other sedatives while using Tessalon Perles, as they can increase the risk of dizziness or drowsiness.

Side Effects of Tessalon Perles

Common Side Effects

  • Drowsiness
  • Dizziness
  • Headache
  • Nausea
  • Constipation


Uncommon/Severe Side Effects

  • Severe allergic reactions (rash, itching, difficulty breathing)
  • Numbness in the mouth or throat (if the capsule is chewed or broken)
  • Seizures
  • Confusion or hallucinations


Risks and Warnings of Tessalon Perles

  • Accidental Ingestion: Ingestion of Tessalon Perles by children under 10 years can result in severe reactions, including seizures, cardiac arrest, and even death. Store the medication securely and out of reach of children.
  • Anesthesia of the Oral Region: Chewing or sucking on the capsule can lead to severe numbing of the mouth and throat, which may cause choking or difficulty swallowing.
  • Overdose Risk: Taking too many capsules can result in serious side effects, including seizures, irregular heart rhythms, and respiratory failure. Contact emergency services immediately if an overdose is suspected.

Interactions with Tessalon Perles

Common Drug Interactions

  • Sedatives and alcohol: Combining Tessalon Perles with sedatives, tranquilizers, or alcohol can increase the risk of drowsiness, dizziness, and confusion.
  • Opioids and CNS depressants: These medications can enhance the central nervous system depression caused by Tessalon Perles, leading to increased sedation or respiratory depression.

Common Food Interactions


Alternatives to Tessalon Perles

  • Dextromethorphan: Another over-the-counter cough suppressant used to treat dry cough.
  • Guaifenesin: An expectorant that helps thin mucus and make coughing more productive, often used for wet or productive coughs.
  • Codeine-based cough syrups: Narcotic cough suppressants used for severe coughs but with the potential for dependence and sedation.
  • Hydrocodone: Another opioid-based cough suppressant for more severe cases, available by prescription only.