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Syeda
Syeda is a combination oral contraceptive that contains two hormones: drospirenone (a progestin) and ethinyl estradiol (an estrogen). Syeda is used to prevent pregnancy by inhibiting ovulation, thickening cervical mucus to block sperm, and altering the uterine lining to prevent a fertilized egg from implanting. It is also used to treat acne in women, regulate menstrual cycles, and reduce the risk of ovarian cysts.
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Frequently Asked Questions
Can I skip the placebo pills to avoid my period?
Yes, you can skip the placebo (inactive) pills and start a new pack immediately if you want to avoid your period. However, consult your healthcare provider before doing this regularly.
What should I do if I miss a dose of Syeda?
If you miss one active pill, take it as soon as you remember. If you miss two or more pills, follow the instructions in the package insert and use a backup contraceptive method (e.g., condoms) for the next 7 days.
Can Syeda help with acne?
Yes, Syeda is also used to treat acne in women who desire contraception, and it is effective at reducing acne breakouts by regulating hormone levels.
Is Syeda safe to use while breastfeeding?
Syeda is generally not recommended while breastfeeding, as it may reduce milk production. A progestin-only pill (mini-pill) or non-hormonal contraceptive is often recommended instead.
Does Syeda protect against sexually transmitted infections (STIs)?
No, Syeda does not protect against STIs. You should use condoms to reduce the risk of infections such as HIV, gonorrhea, and chlamydia.
Comprehensive Drug Guide
How Does Syeda Work?
- Inhibiting ovulation: The progestin and estrogen prevent the release of an egg from the ovary.
- Thickening cervical mucus: This makes it harder for sperm to reach the egg.
- Altering the uterine lining: This prevents the implantation of a fertilized egg, reducing the chances of pregnancy.
Common Dosages
- 3 mg drospirenone / 0.03 mg ethinyl estradiol
Typical Dosing
- For contraception: Take one active tablet daily for 24 days, followed by one placebo tablet daily for 4 days. Begin a new pack immediately after finishing the placebo tablets.
- For acne treatment: Follow the same dosing regimen as for contraception.
Typical Dosing
FDA Approved Indications
- Prevention of pregnancy in women of reproductive age.
- Treatment of moderate acne in women at least 14 years old who desire contraception.
- Regulation of menstrual cycles and relief of menstrual-related symptoms.
Who Shouldn't Take Syeda?
- History of thromboembolic disorders (e.g., deep vein thrombosis or pulmonary embolism)
- Uncontrolled hypertension
- Liver disease or liver tumors
- Known or suspected breast cancer or other hormone-sensitive cancers
- Renal impairment or adrenal insufficiency
- Migraine with aura
- Smoking and age over 35: This combination significantly increases the risk of serious cardiovascular events.
Advice From The Pharmacist
- Take Syeda at the same time every day to maintain consistent hormone levels and maximize contraceptive effectiveness.
- If you miss a pill, take it as soon as you remember. If two or more active pills are missed, use a backup contraceptive method (e.g., condoms) for at least 7 days.
- Avoid smoking while taking Syeda, especially if you are over 35, as smoking increases the risk of blood clots, heart attack, and stroke.
- Monitor for symptoms of blood clots, such as pain, swelling, or redness in the legs, sudden shortness of breath, or chest pain, and contact your healthcare provider immediately if these occur.
- The placebo pills in the pack help to maintain a consistent dosing schedule but do not contain active hormones. Menstrual bleeding typically occurs during the placebo days.
Side Effects of Syeda
Common Side Effects
- Nausea
- Headache
- Breast tenderness
- Weight gain
- Mood changes
- Breakthrough bleeding or spotting
Uncommon/Severe Side Effects
- Blood clots (deep vein thrombosis, pulmonary embolism)
- Stroke or heart attack
- Liver problems, including liver tumors or jaundice
- Severe allergic reactions, including rash, swelling, or difficulty breathing
Risks and Warnings of Syeda
- Cardiovascular Risks: Women over 35 who smoke should not take Syeda, as it significantly increases the risk of serious cardiovascular events, including heart attack, stroke, and blood clots.
- Thromboembolism Risk: Like other combination oral contraceptives, Syeda increases the risk of venous thromboembolism (VTE). Women with a history of blood clots should avoid using Syeda.
- Hyperkalemia: Drospirenone may increase potassium levels in the blood, leading to hyperkalemia. Women with kidney problems or those taking medications that increase potassium levels (e.g., ACE inhibitors) should have their potassium levels monitored.
- Breast Cancer Risk: Hormonal contraceptives may slightly increase the risk of breast cancer in women with a family history or genetic predisposition. Discuss this with your healthcare provider if applicable.
Interactions with Syeda
Common Drug Interactions
- Antibiotics and anticonvulsants: Certain medications, such as rifampin and anticonvulsants (e.g., carbamazepine, phenytoin), can reduce the effectiveness of Syeda, increasing the risk of pregnancy. Use a backup contraceptive method during treatment with these medications.
- St. John’s Wort: This herbal supplement may reduce the effectiveness of Syeda by increasing hormone metabolism.
- Potassium-sparing diuretics: Drospirenone can increase potassium levels, so avoid combining Syeda with medications that raise potassium, such as spironolactone or ACE inhibitors.
Alternatives to Syeda
- Yaz: A similar combination contraceptive that also contains drospirenone and ethinyl estradiol.
- Ortho Tri-Cyclen: A triphasic combination oral contraceptive that includes norgestimate and ethinyl estradiol.
- Nexplanon: A long-acting progestin-only implant used for contraception.
- Mirena IUD: A hormonal intrauterine device that provides long-term birth control.
- NuvaRing: A vaginal ring that releases hormones for contraception.
