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Skyla

Skyla (levonorgestrel) is a hormonal contraceptive device used to prevent pregnancy. It is a intrauterine system (IUS) that releases a low dose of levonorgestrel directly into the uterus. Skyla is designed to provide effective birth control for up to three years and is suitable for women who prefer a long-acting, reversible contraceptive option. By thickening cervical mucus and thinning the uterine lining, Skyla helps to prevent sperm from fertilizing an egg.



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Frequently Asked Questions

How effective is Skyla in preventing pregnancy?
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Skyla is over 99% effective when inserted correctly and used as directed.

Can I become pregnant immediately after Skyla is removed?
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Yes, fertility can return quickly after removal, often within the first menstrual cycle.

What should I do if I experience heavy bleeding?
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Contact your healthcare provider if you have heavy bleeding or severe pain, as it may indicate a problem.

How often do I need to check the placement of Skyla?
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It is advisable to have regular check-ups with your healthcare provider, but you can also check the threads of the IUD monthly.

Does Skyla protect against STIs?
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No, Skyla does not provide protection against sexually transmitted infections. Barrier methods, such as condoms, should be used for STI protection.

Comprehensive Drug Guide

How Does Skyla Work?

  • Thickening of Cervical Mucus: This makes it difficult for sperm to enter the uterus.
  • Thinning of the Uterine Lining: This reduces the likelihood of implantation should fertilization occur.
  • Inhibition of Ovulation: Although not its primary mechanism, it can prevent ovulation in some women.


Common Dosages

  • Intrauterine System: Releases 14 mcg of levonorgestrel per day, effective for up to three years.

Typical Dosing

  • Insertion: Skyla is inserted by a healthcare provider, typically during a routine office visit.
  • Duration: It is effective for up to three years, after which it must be removed or replaced.


Typical Dosing

FDA Approved Indications

  • Prevention of pregnancy in women of reproductive age.


Who Shouldn't Take Skyla?

  • Known hypersensitivity to levonorgestrel or any component of the device.
  • Current or history of breast cancer.
  • Untreated pelvic infections or certain uterine abnormalities.
  • Severe liver disease.


Advice From The Pharmacist

  • After insertion, monitor for any unusual symptoms such as severe pain or heavy bleeding and contact your healthcare provider if they occur.
  • Routine check-ups are recommended to ensure the device remains properly positioned.
  • Skyla does not protect against sexually transmitted infections (STIs), so additional protection may be necessary.
  • It can be removed at any time by a healthcare provider, allowing for a quick return to fertility.


Side Effects of Skyla

Common Side Effects

  • Irregular bleeding or spotting
  • Headache
  • Breast tenderness
  • Nausea


Uncommon/Severe Side Effects

  • Pelvic inflammatory disease (PID)
  • Ectopic pregnancy
  • Severe allergic reactions


Risks and Warnings of Skyla

  • Infection Risk: There is a risk of pelvic infections, particularly in the first few weeks after insertion. Women should be monitored for signs of infection.
  • Ectopic Pregnancy: Although rare, if pregnancy occurs while Skyla is in place, there is an increased risk of ectopic pregnancy.


Interactions with Skyla

Common Drug Interactions

  • Certain Medications: Medications that induce liver enzymes (such as some anticonvulsants and antituberculosis drugs) may reduce the effectiveness of Skyla. Always inform your healthcare provider of all medications you are taking.


Alternatives to Skyla

  • Copper IUD: A non-hormonal option for long-term contraception.
  • Other Hormonal IUDs: Such as Mirena or Liletta, which release different doses of hormones.
  • Hormonal Contraceptive Pills: Oral contraceptives that may suit some women's needs.