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Shingrix
Shingrix is a recombinant zoster vaccine used to prevent shingles (herpes zoster) in adults aged 50 years and older. Shingles is a painful rash caused by the reactivation of the varicella-zoster virus, which also causes chickenpox. Shingrix helps boost the immune system's response to this virus, significantly reducing the risk of developing shingles and its complications.
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Frequently Asked Questions
How effective is Shingrix in preventing shingles?
Shingrix is about 90% effective in preventing shingles and its complications.
Can I receive Shingrix if I have had shingles before?
Yes, individuals who have had shingles can still benefit from receiving Shingrix to help prevent future occurrences.
Are there any specific dietary restrictions while receiving Shingrix?
There are no specific dietary restrictions associated with the administration of Shingrix.
What should I do if I miss a dose of Shingrix?
If you miss the second dose of Shingrix, schedule it as soon as possible. It can be given anytime between 2 to 6 months after the first dose.
Is Shingrix safe for long-term use?
Shingrix is safe and recommended for long-term protection against shingles; however, it is not administered on a continuous basis but rather as a two-dose series. Regular consultation with a healthcare provider is encouraged to monitor ongoing health.
Comprehensive Drug Guide
How Does Shingrix Work?
- Stimulating the immune system: It contains a non-live component of the varicella-zoster virus (VZV) and an adjuvant, which enhances the body’s immune response. This leads to the production of antibodies against the virus, providing protection against shingles.
Common Dosages
- Intramuscular injection: The standard regimen involves two doses, with the second dose given 2 to 6 months after the first dose.
Typical Dosing
- The usual dosing schedule is:
- Dose 1: Administered intramuscularly, followed by
- Dose 2: Administered intramuscularly 2 to 6 months after the first dose.
Typical Dosing
FDA Approved Indications
- Prevention of herpes zoster (shingles) in adults aged 50 years and older.
Who Shouldn't Take Shingrix?
- Known hypersensitivity to any component of the vaccine.
- A history of a severe allergic reaction (e.g., anaphylaxis) to a previous dose of Shingrix or any component.
Advice From The Pharmacist
- Instruct patients on the importance of completing the two-dose series for optimal protection against shingles.
- Advise patients to report any severe reactions following vaccination, including high fever or signs of an allergic reaction.
- Discuss potential side effects, including injection site pain, fatigue, and mild fever, which are generally short-lived.
Side Effects of Shingrix
Common Side Effects
- Pain at the injection site
- Fatigue
- Headache
- Muscle pain
- Fever
Uncommon/Severe Side Effects
- Severe allergic reactions (such as rash, itching, or difficulty breathing).
Risks and Warnings of Shingrix
- Immunocompromised Patients: Shingrix is not recommended for use in individuals with weakened immune systems, such as those undergoing cancer treatment or with advanced HIV/AIDS, unless advised by a healthcare provider.
- Infection Risk: Patients with acute moderate or severe illness should delay vaccination until recovery.
Interactions with Shingrix
Common Drug Interactions
- Other Vaccines: Patients should inform their healthcare provider about any recent vaccinations or planned vaccinations, as timing may need to be adjusted.
Alternatives to Shingrix
- Other Vaccines: Alternatives may include the older Zostavax vaccine, though Shingrix is preferred due to its higher efficacy and safety profile.
